Patents by Inventor RITA MILAZZO

RITA MILAZZO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240269169
    Abstract: The present invention provides compositions and methods for the treatment or prevention of a neurological disease or disorder of the central nervous system (e.g., a storage disorder, lysosomal storage disorder, neurodegenerative disease, etc.) by reconstitution of brain myeloid cell and microglia upon transplantation of hematopoietic cells enriched in microglia reconstitution potential. The invention also provides compositions and methods for ablating and reconstituting microglia.
    Type: Application
    Filed: December 29, 2023
    Publication date: August 15, 2024
    Applicants: The Children's Medical Center Corporation, Ospedale San Raffaele S.r.l., Politecnico di Milano, Fondazione Telethon ETS, Dana-Farber Cancer Institute, Inc.
    Inventors: Alessandra BIFFI, Marco PEVIANI, Davide MOSCATELLI, Alessia CAPOTONDO, Rita MILAZZO, Umberto CAPASSO PALMIERO
  • Patent number: 11957713
    Abstract: The present invention provides compositions and methods for the treatment or prevention of a neurological disease or disorder of the central nervous system (e.g., a storage disorder, lysosomal storage disorder, neurodegenerative disease, etc.) by reconstitution of brain myeloid cell and microglia upon transplantation of hematopoietic cells enriched in microglia reconstitution potential. The invention also provides compositions and methods for ablating and reconstituting microglia.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: April 16, 2024
    Assignees: CHILDREN'S MEDICAL CENTER CORPORATION, OSPEDALE SAN RAFFAELE S.R.L., POLITECNICO DI MILANO, FONDAZIONE TELETHON ETS, DANA-FARBER CANCER INSTITUTE, INC
    Inventors: Alessandra Biffi, Marco Peviani, Davide Moscatelli, Alessia Capotondo, Rita Milazzo, Umberto Capasso Palmiero
  • Publication number: 20200038439
    Abstract: The present invention provides compositions and methods for the treatment or prevention of a neurological disease or disorder of the central nervous system (e.g., a storage disorder, lysosomal storage disorder, neurodegenerative disease, etc.) by reconstitution of brain myeloid cell and microglia upon transplantation of hematopoietic cells enriched in microglia reconstitution potential. The invention also provides compositions and methods for ablating and reconstituting microglia.
    Type: Application
    Filed: October 16, 2017
    Publication date: February 6, 2020
    Applicants: CHILDREN'S MEDICAL CENTER CORPORATION, OSPEDALE SAN RAFFAELE S.R.L., POLITECNICO DI MILANO, FONDAZIONE TELETHON
    Inventors: ALESSANDRA BIFFI, MARCO PEVIANI, DAVIDE MOSCATELLI, ALESSIA CAPATANDO, RITA MILAZZO, UMBERTO CAPASSO PALMIERO