Patents by Inventor Rita Pfeifer

Rita Pfeifer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric antigen receptor with a spacer comprising C2-set Ig-like domains
    Patent number: 12286465
    Abstract: Provided herein are chimeric antigen receptors (CARs) that include a) an antigen binding domain specific for an antigen, b) a spacer, c) a transmembrane domain, and d) an intracellular signaling domain, wherein the spacer consists of 1, 2 or 3 C2-set Ig-like domain(s) e.g., C2-set Ig-like domains of the sialic acid binding Ig-like lectin (Siglec) family. Also provided herein are compositions including a) an immune cell expressing a CAR, wherein the CAR is specific for a tag and b) a tagged polypeptide.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: April 29, 2025
    Assignee: Miltenyi Biotec B.V. & Co. KG
    Inventors: Rita Pfeifer, Daniel Schäfer, Ian Johnston
  • Chimeric antigen receptor with a spacer comprising C2-set Ig-like domains
    Publication number: 20210371490
    Abstract: The present invention provides a CAR comprising a) an antigen binding domain specific for an antigen, b) a spacer, c) a transmembrane domain, and d) an intracellular signaling domain, wherein said spacer consists of 1, 2 or 3 C2-set Ig-like domain(s). Said C2-set Ig-like domain(s) may be selected from the group of C2-set Ig-like domains of the sialic acid binding Ig-like lectin (Siglec) family. A composition comprising a) an immune cell expressing said CAR, wherein said CAR is specific for a tag and b) a tagged polypeptide is also disclosed.
    Type: Application
    Filed: May 27, 2021
    Publication date: December 2, 2021
    Inventors: Rita Pfeifer, Daniel Schäfer, Ian Johnston