Patents by Inventor Rita T. Bradley

Rita T. Bradley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of a reversibly inactive acidified plasmin composition
    Patent number: 7544500
    Abstract: Disclosed is both a process for producing a reversibly inactive acidified plasmin by activating plasminogen and a process for producing a purified plasminogen. The produced plasmin is isolated and stored with a low pH-buffering capacity agent to provide a substantially stable formulation. The purified plasminogen is typically purified from a fraction obtained in the separation of immunoglobulin from Fraction II+III chromatographic process and eluted at a low pH. The reversibly inactive acidified plasmin may be used in the administration of a thrombolytic therapy.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: June 9, 2009
    Assignee: Talecris Biotherapeutics, Inc.
    Inventors: Rita T. Bradley, Scott A. Cook, Christopher A. Dadd, Jonathan D. Kent, Marina N. Korneyeva, Valery V. Novokhatny, James F. Rebbeor, Christopher J. Stenland, Jonathan S. Strauss, Jarrett C. Terry, Jeffrey A. Yuziuk
  • Process for the production of a reversibly inactive acidified plasmin composition
    Publication number: 20040171103
    Abstract: Disclosed is both a process for producing a reversibly inactive acidified plasmin by activating plasminogen and a process for producing a purified plasminogen. The produced plasmin is isolated and stored with a low pH-buffering capacity agent to provide a substantially stable formulation. The purified plasminogen is typically purified from a fraction obtained in the separation of immunoglobulin from Fraction II+III chromatographic process and eluted at a low pH. The reversibly inactive acidified plasmin may be used in the administration of a thrombolytic therapy.
    Type: Application
    Filed: October 23, 2003
    Publication date: September 2, 2004
    Inventors: Rita T. Bradley, Scott A. Cook, Christopher A. Dadd, Jonathan D. Kent, Marina N. Korneyeva, Valery V. Novokhatny, James F. Rebbeor, Christopher J. Stenland, Jonathan S. Strauss, Jarrett C. Terry, Jeffrey A. Yuziuk
  • Process for the production of a reversibly inactive acidified plasmin composition
    Publication number: 20020192794
    Abstract: Disclosed is both a process for producing a reversibly inactive acidified plasmin by activating plasminogen and a process for producing a purified plasminogen. The produced plasmin is isolated and stored with a low pH-buffering capacity agent to provide a substantially stable formulation. The purified plasminogen is typically purified from a fraction obtained in the separation of immunoglobulin from Fraction II+III chromatographic process and eluded at a low pH. The reversibly inactive acidified plasmin may be used in the administration of a thrombolytic therapy.
    Type: Application
    Filed: May 10, 2002
    Publication date: December 19, 2002
    Inventors: Christopher A. Dadd, Christopher J. Stenland, Jonathan D. Kent, Marina N. Korneyeva, George A. Baumbach, Scoot A. Cook, Rita T. Bradley, Valery Novokhatny, Tanette B. Villines