Patents by Inventor Rituraj Singh
Rituraj Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190050673Abstract: In many real-life applications, ample amount of examples from one class are present while examples from other classes are rare for training and learning purposes leading to class imbalance problem and misclassification. Methods and systems of the present disclosure facilitate generation of an extended synthetic rare class super dataset that is further pruned to obtain a synthetic rare class dataset by maximizing similarity and diversity in the synthetic rare class dataset while preserving morphological identity with labeled rare class training dataset. Oversampling methods used in the art result in cloning of datasets and do not provide the needed diversity. The methods of the present disclosure can be applied to classification of noisy phonocardiogram (PCG) signals among other applications.Type: ApplicationFiled: August 13, 2018Publication date: February 14, 2019Applicant: Tata Consultancy Services LimitedInventors: Arijit UKIL, Soma Bandyopadhyay, Chetanya Puri, Rituraj Singh, Arpan Pal
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Publication number: 20190050690Abstract: Absence of well-represented training datasets cause a class imbalance problem in one-class support vector machines (OC-SVMs). The present disclosure addresses this challenge by computing optimal hyperparameters of the OC-SVM based on imbalanced training sets wherein one of the class examples outnumbers the other class examples. The hyperparameters kernel co-efficient ? and rejection rate hyperparameter ? of the OC-SVM are optimized to trade-off the maximization of classification performance while maintaining stability thereby ensuring that the optimized hyperparameters are not transient and provide a smooth non-linear decision boundary to reduce misclassification as known in the art. This finds application particularly in clinical decision making such as detecting cardiac abnormality condition under practical conditions of contaminated inputs and scarcity of well-represented training datasets.Type: ApplicationFiled: March 15, 2018Publication date: February 14, 2019Applicant: Tata Consultancy Services LimitedInventors: Arijit UKIL, Soma BANDYOPADHYAY, Chetanya PURI, Rituraj SINGH, Arpan PAL
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Patent number: 10172528Abstract: This disclosure relates generally to biomedical signal processing, and more particularly to method and system for physiological parameter derivation from pulsating signals with reduced error. In this method, pulsating signals are extracted, spurious perturbations in the extracted pulsating signals are removed for smoothening, local minima points in the smoothened pulsating signal are derived, systolic maxima point between two derived local minima are derived, most probable pulse duration and most probable peak-to-peak distance are derived, dicrotic minima is removed while ensuring that every dicrotic minima is preceded by a systolic maxima point and followed by a beat start point of said systolic maxima, diastolic peak is derived while ensuring that every dicrotic maxima is preceded by a diastolic notch followed by next beat start point of that maxima, and physiological parameters are derived from the derived local minima points, systolic maxima points, dicrotic notch and diastolic peak.Type: GrantFiled: March 23, 2017Date of Patent: January 8, 2019Assignee: Tata Consultancy Services LimitedInventors: Soma Bandyopadhyay, Arijit Ukil, Chetanya Puri, Rituraj Singh, Arpan Pal, C A Murthy, Kayapanda Mandana
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Patent number: 10174367Abstract: The present disclosure provides methods, devices and systems that enable simultaneous multiplexing amplification reaction and real-time detection in a single reaction chamber.Type: GrantFiled: October 12, 2016Date of Patent: January 8, 2019Assignee: INSILIXA, INC.Inventors: Arjang Hassibi, Kshama Jirage, Arun Manickam, Rituraj Singh
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Publication number: 20180335399Abstract: A biosensor pixel for measuring current that flows through the electrode surface in response to electrochemical interactions and a biosensor array architecture that includes such biosensor pixels. The biosensor pixel includes an electrode transducer configured to measure a current generated by electrochemical interactions occurring at a recognition layer placed directly on top of it in response to an electrical voltage placed across an electrode transducer-electrolyte interface. The biosensor pixel further includes a trans-impedance amplifier connected to the electrode transducer, where the trans-impedance amplifier is configured to convert the current into a voltage signal as the electrochemical interactions occur.Type: ApplicationFiled: April 24, 2018Publication date: November 22, 2018Inventors: Arjang Hassibi, Arun Manickam, Rituraj Singh
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Publication number: 20180153419Abstract: This disclosure relates generally to physiological monitoring, and more particularly to feature set optimization for classification of physiological signal. In one embodiment, a method for physiological monitoring includes identifying clean physiological signal training set from an input physiological signal based on a Dynamic Time Warping (DTW) of segments associated with the physiological signal. An optimal features set is extracted from a clean physiological signal training set based on a Maximum Consistency and Maximum Dominance (MCMD) property associated with the optimal feature set that strictly optimizes on the objective function, the conditional likelihood maximization over different selection criteria such that diverse properties of different selection parameters are captured and achieves Pareto-optimality. The input physiological signal is classified into normal signal components and abnormal signal components using the optimal features set.Type: ApplicationFiled: December 1, 2017Publication date: June 7, 2018Applicant: Tata Consultancy Services LimitedInventors: Arijit UKIL, Soma BANDYOPADHYAY, Chetanya PURI, Rituraj SINGH, Arpan PAL, Debayan MUKHERJEE
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Patent number: 9983163Abstract: A biosensor pixel for measuring current that flows through the electrode surface in response to electrochemical interactions and a biosensor array architecture that includes such biosensor pixels. The biosensor pixel includes an electrode transducer configured to measure a current generated by electrochemical interactions occurring at a recognition layer placed directly on top of it in response to an electrical voltage placed across an electrode transducer-electrolyte interface. The biosensor pixel further includes a trans-impedance amplifier connected to the electrode transducer, where the trans-impedance amplifier is configured to convert the current into a voltage signal as the electrochemical interactions occur.Type: GrantFiled: April 30, 2013Date of Patent: May 29, 2018Assignee: Board of Regents, The University of Texas SystemInventors: Arjang Hassibi, Arun Manickam, Rituraj Singh
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Patent number: 9978392Abstract: Traditionally known classification methods of non-stationary physiological audio signals as noisy and clean involve human intervention, may involve dependency on particular type of classifier and further analyses is carried out on classified clean signals. However, in non-stationary audio signals a major portion may end up being classified as noisy and hence may get rejected which may cause missing of intelligence which could have been derived from lightly noisy audio signals that may be critical. The present disclosure enables automation of classification based on auto-thresholding and statistical isolation wherein noisy signals are further classified as highly noisy and lightly noisy through continuous dynamic learning.Type: GrantFiled: March 10, 2017Date of Patent: May 22, 2018Assignee: Tata Consultancy Services LimitedInventors: Arijit Ukil, Soma Bandyopadhyay, Chetanya Puri, Arpan Pal, Rituraj Singh, Ayan Mukherjee, Debayan Mukherjee
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Publication number: 20180110471Abstract: Accurate detection of anomaly in sensor signals is critical and can have an immense impact in the health care domain. Accordingly, identifying outliers or anomalies with reduced error and reduced resource usage is a challenge addressed by the present disclosure. Self-learning of normal signature of an input sensor signal is used to derive primary features based on valley and peak points of the sensor signals. A pattern is recognized by using discrete nature and strictly rising and falling edges of the input sensor signal. One or more defining features are identified from the derived features based on statistical properties and time and frequency domain properties of the input sensor signal. Based on the values of the defining features, clusters of varying density are identified for the input sensor signal and based on the density of the clusters, anomalous and non-anomalous portions of the input sensor signals are classified.Type: ApplicationFiled: March 10, 2017Publication date: April 26, 2018Applicant: Tata Consultancy Services LimitedInventors: Soma Bandyopadhyay, Arijit Ukil, Rituraj Singh, Chetanya Puri, Arpan Pai, C. A. Murthy
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Publication number: 20180075861Abstract: Traditionally known classification methods of non-stationary physiological audio signals as noisy and clean involve human intervention, may involve dependency on particular type of classifier and further analyses is carried out on classified clean signals. However, in non-stationary audio signals a major portion may end up being classified as noisy and hence may get rejected which may cause missing of intelligence which could have been derived from lightly noisy audio signals that may be critical. The present disclosure enables automation of classification based on auto-thresholding and statistical isolation wherein noisy signals are further classified as highly noisy and lightly noisy through continuous dynamic learning.Type: ApplicationFiled: March 10, 2017Publication date: March 15, 2018Applicant: Tata Consultancy Services LimitedInventors: Arijit Ukil, Soma Bandyopadhyay, Chetanya Puri, Arpan Pal, Rituraj Singh, Ayan Mukherjee, Debayan Mukherjee
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Publication number: 20170340211Abstract: This disclosure relates generally to biomedical signal processing, and more particularly to method and system for physiological parameter derivation from pulsating signals with reduced error. In this method, pulsating signals are extracted, spurious perturbations in the extracted pulsating signals are removed for smoothening, local minima points in the smoothened pulsating signal are derived, systolic maxima point between two derived local minima are derived, most probable pulse duration and most probable peak-to-peak distance are derived, dicrotic minima is removed while ensuring that every dicrotic minima is preceded by a systolic maxima point and followed by a beat start point of said systolic maxima, diastolic peak is derived while ensuring that every dicrotic maxima is preceded by a diastolic notch followed by next beat start point of that maxima, and physiological parameters are derived from the derived local minima points, systolic maxima points, dicrotic notch and diastolic peak.Type: ApplicationFiled: March 23, 2017Publication date: November 30, 2017Applicant: Tata Consultancy Services LimitedInventors: Soma BANDYOPADHYAY, Arijit UKIL, Chetanya PURI, Rituraj SINGH, Arpan PAL, C. A. MURTHY, Kayapanda MANDANA
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Publication number: 20170101666Abstract: The present disclosure provides methods, devices and systems that enable simultaneous multiplexing amplification reaction and real-time detection in a single reaction chamber.Type: ApplicationFiled: October 12, 2016Publication date: April 13, 2017Inventors: Arjang HASSIBI, Kshama JIRAGE, Arun MANICKAM, Rituraj SINGH
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Patent number: 9499861Abstract: The present disclosure provides methods, devices and systems that enable simultaneous multiplexing amplification reaction and real-time detection in a single reaction chamber.Type: GrantFiled: September 10, 2015Date of Patent: November 22, 2016Assignee: InSilixa, Inc.Inventors: Arjang Hassibi, Kshama Jirage, Arun Manickam, Rituraj Singh
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Patent number: 9465002Abstract: A method and device for performing DNA sequencing and extracting structural information from unknown nucleic acid strands. The device includes a microwell structure, where identical DNA strands are immobilized within the microwell structure on a surface of a micro-bead, an active electrode or a porous polymer. The device further includes a CMOS-integrated semiconductor integrated circuit, where the CMOS-integrated semiconductor integrated circuit includes metal layers on a silicon substrate, where the metal layers form an active electrode biosensor. In addition, a sensing electrode is formed by creating openings in a passivation layer of the CMOS-integrated semiconductor integrated circuit to hold a single bead, on which the DNA strands are immobilized.Type: GrantFiled: August 5, 2013Date of Patent: October 11, 2016Assignee: Board of Regents, The University of Texas SystemInventors: Arjang Hassibi, Arun Manickam, Rituraj Singh
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Publication number: 20160231270Abstract: A method and device for performing DNA sequencing and extracting structural information from unknown nucleic acid strands. The device includes a microwell structure, where identical DNA strands are immobilized within the microwell structure on a surface of a micro-bead, an active electrode or a porous polymer. The device further includes a CMOS-integrated semiconductor integrated circuit, where the CMOS-integrated semiconductor integrated circuit includes metal layers on a silicon substrate, where the metal layers form an active electrode biosensor. In addition, a sensing electrode is formed by creating openings in a passivation layer of the CMOS-integrated semiconductor integrated circuit to hold a single bead, on which the DNA strands are immobilized.Type: ApplicationFiled: April 12, 2016Publication date: August 11, 2016Inventors: Arjang Hassibi, Arun Manickam, Rituraj Singh
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Patent number: 9341589Abstract: A method and device for performing DNA sequencing and extracting structural information from unknown nucleic acid strands. The device includes a microwell structure, where identical DNA strands are immobilized within the microwell structure on a surface of a micro-bead, an active electrode or a porous polymer. The device further includes a CMOS-integrated semiconductor integrated circuit, where the CMOS-integrated semiconductor integrated circuit includes metal layers on a silicon substrate, where the metal layers form an active electrode biosensor. In addition, a sensing electrode is formed by creating openings in a passivation layer of the CMOS-integrated semiconductor integrated circuit to hold a single bead, on which the DNA strands are immobilized.Type: GrantFiled: June 20, 2012Date of Patent: May 17, 2016Assignee: Board of Regents, The University of Texas SystemInventors: Arjang Hassibi, Arun Manickam, Rituraj Singh
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Patent number: 8969781Abstract: An optical biosensor pixel for detecting the amount of light that is generated by the biosensing process and a biosensor array architecture that includes such biosensor pixels. The optical biosensor pixel includes a photodiode configured to convert an incident photon flux into a current. Additionally, the optical biosensor pixel includes an optical filter configured to select specific wavelengths and/or photon flux angles to reach the photodiode from a biological sample. The biosensor pixel further includes a trans-impedance amplifier coupled to the photodiode, where the trans-impedance amplifier is configured to convert the current into a voltage signal. Additionally, the biosensor pixel includes a 1-bit comparator coupled to the trans-impedance amplifier and a 1-bit digital-to-analog converter coupled to the 1-bit comparator, where the 1-bit digital-to-analog converter injects different levels of charge into an input of the trans-impedance amplifier at each cycle based on an output of the 1-bit comparator.Type: GrantFiled: June 28, 2012Date of Patent: March 3, 2015Assignee: Board of Regents, The University of Texas SystemInventors: Arjang Hassibi, Rituraj Singh, Arun Manickam
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Publication number: 20140318958Abstract: A biosensor pixel for measuring current that flows through the electrode surface in response to electrochemical interactions and a biosensor array architecture that includes such biosensor pixels. The biosensor pixel includes an electrode transducer configured to measure a current generated by electrochemical interactions occurring at a recognition layer placed directly on top of it in response to an electrical voltage placed across an electrode transducer-electrolyte interface. The biosensor pixel further includes a trans-impedance amplifier connected to the electrode transducer, where the trans-impedance amplifier is configured to convert the current into a voltage signal as the electrochemical interactions occur.Type: ApplicationFiled: April 30, 2013Publication date: October 30, 2014Applicant: Board of Regents, The University of Texas SystemInventors: Arjang Hassibi, Arun Manickam, Rituraj Singh
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Publication number: 20140011710Abstract: A method and device for performing DNA sequencing and extracting structural information from unknown nucleic acid strands. The device includes a microwell structure, where identical DNA strands are immobilized within the microwell structure on a surface of a micro-bead, an active electrode or a porous polymer. The device further includes a CMOS-integrated semiconductor integrated circuit, where the CMOS-integrated semiconductor integrated circuit includes metal layers on a silicon substrate, where the metal layers form an active electrode biosensor. In addition, a sensing electrode is formed by creating openings in a passivation layer of the CMOS-integrated semiconductor integrated circuit to hold a single bead, on which the DNA strands are immobilized.Type: ApplicationFiled: August 5, 2013Publication date: January 9, 2014Applicant: Board of Regents, The University of Texas SystemInventors: Arjang Hassibi, Arun Manickam, Rituraj Singh
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Publication number: 20140001341Abstract: An optical biosensor pixel for detecting the amount of light that is generated by the biosensing process and a biosensor array architecture that includes such biosensor pixels. The optical biosensor pixel includes a photodiode configured to convert an incident photon flux into a current. Additionally, the optical biosensor pixel includes an optical filter configured to select specific wavelengths and/or photon flux angles to reach the photodiode from a biological sample. The biosensor pixel further includes a trans-impedance amplifier coupled to the photodiode, where the trans-impedance amplifier is configured to convert the current into a voltage signal. Additionally, the biosensor pixel includes a 1-bit comparator coupled to the trans-impedance amplifier and a 1-bit digital-to-analog converter coupled to the 1-bit comparator, where the 1-bit digital-to-analog converter injects different levels of charge into an input of the trans-impedance amplifier at each cycle based on an output of the 1-bit comparator.Type: ApplicationFiled: June 28, 2012Publication date: January 2, 2014Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Arjang Hassibi, Rituraj Singh, Arun Manickam