Patents by Inventor Riyong QIU

Riyong QIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PQQ-sGDH mutant, polynucleotide and glucose detection biosensor
    Patent number: 10752934
    Abstract: The present invention provides a soluble pyrroloquinoline-quinone-dependent glucose dehydrogenase (PQQ-sGDH) mutant, wherein the amino acid positions thereof correspond to a wild-type PQQ-sGDH sequence of Acinetobacter calcoaceticus as shown in SEQ ID NO 1 comprising one of the following group of mutations: A194F, a combined mutation based on A194F, a combined mutation based on Q192A or a combined mutation based on Q192S. Said PQQ-sGDH mutant has good glucose substrate specificity and significantly reduced cross-reactivity to maltose and the like, and is suitable for detecting glucose in a sample such as blood.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: August 25, 2020
    Assignee: LEADWAY (HK) LIMITED
    Inventors: Zhe Wang, Xin Bi, Riyong Qiu
  • PQQ-sGDH MUTANT, POLYNUCLEOTIDE AND GLUCOSE DETECTION BIOSENSOR
    Publication number: 20190390247
    Abstract: The present invention provides a soluble pyrroloquinoline-quinone-dependent glucose dehydrogenase (PQQ-sGDH) mutant, wherein the amino acid positions thereof correspond to a wild-type PQQ-sGDH sequence of Acinetobacter calcoaceticus as shown in SEQ ID NO 1 comprising one of the following group of mutations: A194F, a combined mutation based on A194F, a combined mutation based on Q192A or a combined mutation based on Q192S. Said PQQ-sGDH mutant has good glucose substrate specificity and significantly reduced cross-reactivity to maltose and the like, and is suitable for detecting glucose in a sample such as blood.
    Type: Application
    Filed: October 28, 2016
    Publication date: December 26, 2019
    Applicant: LEADWAY (HK) LIMITED
    Inventors: Zhe WANG, Xin BI, Riyong QIU