Patents by Inventor Rizwan Masood

Rizwan Masood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEVELOPMENT OF PROGNOSTIC MARKERS DSG-3 FROM THE SALIVA OF ORAL CANCER PATIENTS
    Publication number: 20180321248
    Abstract: A method for the early detection of head and neck cancer is provided. The method includes obtaining a saliva sample from a subject, determining the expression level of Desmoglien 3 (DSG3) in the saliva sample, and detecting head and neck cancer by the expression level of DSG3.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 8, 2018
    Inventors: Uttam K. SINHA, Rizwan MASOOD
  • Compositions and Methods of Sphingosine Kinase Inhibitors In Radiation Therapy of Various Cancers
    Publication number: 20120259150
    Abstract: The present invention relates to Sphingosine kinase inhibitors that are useful for treating various cancers. The invention further relates to compositions and methods of SPK inhibitors, including siRNAs, which specifically block gene expression of SPK and potentiates the effect of radiation in the treatment of various cancers.
    Type: Application
    Filed: November 23, 2011
    Publication date: October 11, 2012
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Uttam K. SINHA, Rizwan MASOOD
  • Compositions and methods of sphingosine kinase inhibitors in radiation therapy of various cancers
    Patent number: 8084438
    Abstract: The present invention relates to Sphingosine kinase inhibitors that are useful for treating various cancers. The invention further relates to compositions and methods of SPK inhibitors, including siRNAs, which specifically block gene expression of SPK and potentiates the effect of radiation in the treatment of various cancers.
    Type: Grant
    Filed: May 3, 2010
    Date of Patent: December 27, 2011
    Assignee: University of Southern California
    Inventors: Uttam K. Sinha, Rizwan Masood
  • Development of prognostic markers from the saliva of head and neck cancer patients
    Patent number: 7910293
    Abstract: The present invention relates to biomarkers that are useful for the detection of cancer. The invention further relates to biomarkers and methods of using biomarkers for the early detection of head and neck cancer.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: March 22, 2011
    Assignee: University of Southern California
    Inventors: Uttam K. Sinha, Rizwan Masood
  • METHODS AND COMPOSITONS FOR ANTISENSE VEGF OLIGONUCLEOTIDES
    Publication number: 20100330152
    Abstract: This invention relates to compositions and methods for inhibition of abnormal proliferation of cells or angiogenesis. More particularly this invention provides VEGF antisense oligonucleotides capable of inhibiting proliferation of cancer cells or angiogenesis or combinations thereof. also provided are screening and prognostic assays, as well kits comprising the VEGF antisense oligonucleotides.
    Type: Application
    Filed: October 5, 2009
    Publication date: December 30, 2010
    Applicant: VasGene Therapeutics, Inc.
    Inventors: Parkash Gill, Rizwan Masood, Sudhir Agrawal
  • COMPOSITIONS AND METHODS OF SPHINGOSINE KINASE INHIBITORS IN RADIATION THERAPY OF VARIOUS CANCERS
    Publication number: 20100331393
    Abstract: The present invention relates to Sphingosine kinase inhibitors that are useful for treating various cancers. The invention further relates to compositions and methods of SPK inhibitors, including siRNAs, which specifically block gene expression of SPK and potentiates the effect of radiation in the treatment of various cancers.
    Type: Application
    Filed: May 3, 2010
    Publication date: December 30, 2010
    Applicant: University of Southern California
    Inventors: Uttam K. Sinha, Rizwan Masood
  • Development of Diagnostic Markers From the Saliva of Head and Neck Cancer Patients
    Publication number: 20100099102
    Abstract: The present invention relates to biomarkers that are useful for the detection of cancer. The invention further relates to biomarkers and methods of using biomarkers for the early detection of head and neck cancer.
    Type: Application
    Filed: September 28, 2009
    Publication date: April 22, 2010
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Uttam K. Sinha, Rizwan Masood
  • DEVELOPMENT OF PROGNOSTIC MARKERS FROM THE SALIVA OF HEAD AND NECK CANCER PATIENTS
    Publication number: 20090246761
    Abstract: The present invention relates to biomarkers that are useful for the detection of cancer. The invention further relates to biomarkers and methods of using biomarkers for the early detection of head and neck cancer.
    Type: Application
    Filed: March 28, 2008
    Publication date: October 1, 2009
    Applicant: University of Southern California
    Inventors: Uttam K. SINHA, Rizwan Masood
  • COMPOSITIONS AND METHODS OF SPHINGOSINE KINASE INHIBITORS FOR USE THEREOF IN CANCER THERAPY
    Publication number: 20090048195
    Abstract: The present invention relates to Sphingosine kinase inhibitors that are useful for treating various cancers. The invention specifically relates to compositions and methods of SPK inhibitors, including siRNAs, which specifically block gene expression of SPK and induce apoptosis in a variety of cancers.
    Type: Application
    Filed: November 30, 2007
    Publication date: February 19, 2009
    Applicant: University of Southern California
    Inventors: Uttam K. Sinha, Rizwan Masood
  • COMPOSITIONS AND METHODS OF SPHINGOSINE KINASE INHIBITORS IN RADIATION THERAPY OF VARIOUS CANCERS
    Publication number: 20080261907
    Abstract: The present invention relates to Sphingosine kinase inhibitors that are useful for treating various cancers. The invention further relates to compositions and methods of SPK inhibitors, including siRNAs, which specifically block gene expression of SPK and potentiates the effect of radiation in the treatment of various cancers.
    Type: Application
    Filed: November 30, 2007
    Publication date: October 23, 2008
    Applicant: University of Southern California
    Inventors: Uttam K. Sinha, Rizwan Masood
  • IL-8 is an autocrine growth factor and a surrogate marker for Kaposi's sarcoma
    Publication number: 20030096781
    Abstract: Methods for treating and diagnosing Kaposi's sarcoma are provided. In one embodiment the invention provides a method of treating disease wherein the method comprises modulation of IL-8. The disease to be treated may be a disease such as Kaposi's sarcoma. In one embodiment, the invention comprises administering a therapeutic composition comprising IL-8 antisense oligonucleotides. The invention also provides a method of diagnosing Kaposi's sarcoma wherein the method comprises measuring the expression level of IL-8.
    Type: Application
    Filed: August 30, 2002
    Publication date: May 22, 2003
    Applicant: University of Southern California
    Inventors: Rizwan Masood, Parkash S. Gill
  • Methods and compositions for antisense VEGF oligonucleotides
    Publication number: 20020165174
    Abstract: This invention relates to compositions and methods for inhibition of abnormal proliferation of cells or angiogenesis. More particularly this invention provides VEGF antisense oligonucleotides capable of inhibiting proliferation of cancer cells or angiogenesis or combinations thereof. also provided are screening and prognostic assays, as well kits comprising the VEGF antisense oligonucleotides.
    Type: Application
    Filed: March 13, 2001
    Publication date: November 7, 2002
    Inventors: Parkash S. Gill, Rizwan Masood
  • Method and composition for treatment of kaposi's sarcoma
    Patent number: 6291667
    Abstract: A novel method of treating Kaposi's sarcoma (KS) in patients, by administration of an effective amount of VEGF antagonist/s. VEGF antagonists are capable of inhibiting the growth of KS cells in culture by inhibiting the production of VEGF, or by interfering with the binding of VEGF to its cognate receptors or interfere with the biological effects of VEGF. The VEGF antagonist may be administered to KS patients topically, orally, or parentally. Other VEGF antagonist such as VEGF antibodies, VEGF receptor antibodies, soluble forms of VEGF receptors that bind VEGF away from the cells, or agents that inhibit the signal of VEGF into the cell such as protein kinase inhibitors etc. can also be used The novel antisense oligonucleotides (Veglin-1 and Veglin-3) may also be used to inhibit VEGF and thus new blood vessel formation in diseases such as tumors, proliferative retinopathy, or collagen vascular diseases such as rheumatoid arthritis, and skin diseases such as pemphigus and psoriasis.
    Type: Grant
    Filed: January 30, 1998
    Date of Patent: September 18, 2001
    Inventors: Parkash S. Gill, Rizwan Masood