Patents by Inventor Roa-Pu Shen

Roa-Pu Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • transformant for producing itaconate and uses thereof
    Patent number: 10982238
    Abstract: The present disclosure provides an Escherichia coli transformant and a method for producing itaconate using the Escherichia coli transformant.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: April 20, 2021
    Assignees: NATIONAL TSING HUA UNIVERSITY, CHANG CHUN PLASTICS CO., LTD., CHANG CHUN PETROCHEMICAL CO., LTD., DAIREN CHEMICAL CORPORATION
    Inventors: Roa-Pu Shen, Wei Lu, Tung-Yu Wang
  • ESCHERICHIA COLI TRANSFORMANT FOR PRODUCING ITACONATE AND USES THEREOF
    Publication number: 20200325503
    Abstract: The present disclosure provides an Escherichia coli transformant and a method for producing itaconate using the Escherichia coli transformant.
    Type: Application
    Filed: July 19, 2019
    Publication date: October 15, 2020
    Inventors: Roa-Pu Shen, Wei Lu, Tung-Yu Wang
  • Butanol expression cassette, recombinant plasmid and butanol production related gene expression method
    Patent number: 10633677
    Abstract: A butanol expression cassette includes a butanol production related genes and a fermentation regulatory element. The fermentation regulatory element controls the expression of the butanol production related gene and locates upstream of the butanol production related gene. The fermentation regulatory element includes a promoter, a ribosome binding site and a transcription factor binding site of a fermentation gene. A fermentation in which the fermentation regulatory element involves includes an acetic acid fermentation, an alcohol fermentation, a succinic acid fermentation or a lactic acid fermentation, the butanol production related gene is not the fermentation gene or a gene of an upstream product of the fermentation in which the fermentation gene involves. The present invention provides a recombinant plasmid formed by cloning the butanol expression cassettes in the expression vector.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: April 28, 2020
    Assignees: National Tsing Hua University, Chang Chun Plastics Co., Ltd., Chang Chun Petrochemical Co., Ltd.
    Inventors: Roa-Pu Shen, Rex C. Wen
  • Engineered cyanobacterium and its application for producing acetate
    Patent number: 10570425
    Abstract: The present invention provides an engineered cyanobacterium, comprising at least one plasmid selected from three novel pathways to produce acetate, which can convert atmospheric carbon dioxide as a raw material into acetate. The present invention also constructs the expression plasmid for three different transporters specific to acetate to be expressed in cyanobacteria, which comprises putative ABC transporter (AatA), succinate/acetate: proton symporter (SatP) and acetate/glycolate: cation symporter (ActP). Therefore, the engineered cyanobacteria of the present invention can produce 0.58 mg/L to 3.54 mg/L of acetate per hour.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: February 25, 2020
    Assignees: NATIONAL TSING HUA UNIVERSITY, CHANG CHUN PLASTICS CO., LTD., CHANG CHUN PETROCHEMICAL CO., LTD.
    Inventors: Roa-Pu Shen, Wei Lu
  • ENGINEERED CYANOBACTERIUM AND ITS APPLICATION FOR PRODUCING ACETATE
    Publication number: 20190040424
    Abstract: The present invention provides an engineered cyanobacterium, comprising at least one plasmid selected from three novel pathways to produce acetate, which can convert atmospheric carbon dioxide as a raw material into acetate. The present invention also constructs the expression plasmid for three different transporters specific to acetate to be expressed in cyanobacteria, which comprises putative ABC transporter (AatA), succinate/acetate: proton symporter (SatP) and acetate/glycolate: cation symporter (ActP). Therefore, the engineered cyanobacteria of the present invention can produce 0.58 mg/L to 3.54 mg/L of acetate per hour.
    Type: Application
    Filed: December 28, 2017
    Publication date: February 7, 2019
    Inventors: Roa-Pu Shen, Wei Lu
  • BUTANOL EXPRESSION CASSETTE, RECOMBINANT PLASMID AND BUTANOL PRODUCTION RELATED GENE EXPRESSION METHOD
    Publication number: 20180179556
    Abstract: A butanol expression cassette includes a butanol production related genes and a fermentation regulatory element. The fermentation regulatory element controls the expression of the butanol production related gene and locates upstream of the butanol production related gene. The fermentation regulatory element includes a promoter, a ribosome binding site and a transcription factor binding site of a fermentation gene. A fermentation in which the fermentation regulatory element involves includes an acetic acid fermentation, an alcohol fermentation, a succinic acid fermentation or a lactic acid fermentation, the butanol production related gene is not the fermentation gene or a gene of an upstream product of the fermentation in which the fermentation gene involves. The present invention provides a recombinant plasmid formed by cloning the butanol expression cassettes in the expression vector.
    Type: Application
    Filed: May 18, 2017
    Publication date: June 28, 2018
    Applicants: National Tsing Hua University, Chang Chun Plastics Co., Ltd., Chang Chun Petrochemical Co., Ltd.
    Inventors: Roa-Pu Shen, Rex C. Wen