Patents by Inventor Roarke W. Horstmeyer

Roarke W. Horstmeyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220254538
    Abstract: Systems, devices, and methods of Fourier ptychographic imaging by computationally reconstructing a high-resolution image by iteratively updating overlapping regions of variably-illuminated, low-resolution intensity images in Fourier space.
    Type: Application
    Filed: November 18, 2021
    Publication date: August 11, 2022
    Applicant: California Institute of Technology
    Inventors: Guoan Zheng, Changhuei Yang, Roarke W. Horstmeyer
  • Patent number: 10718934
    Abstract: Certain aspects pertain to epi-illumination Fourier ptychographic imaging systems and methods for high resolution imaging of thick samples.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: July 21, 2020
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Roarke W. Horstmeyer, Changhuei Yang
  • Patent number: 10665001
    Abstract: Certain aspects pertain to Fourier ptychographic tomographic systems and methods for acquiring a plurality of uniquely illuminated intensity measurements based on light passing through a thick sample from plane wave illumination at different angles and for constructing three-dimensional tomographic data of the thick sample by iteratively determining three-dimensional tomographic data in the Fourier domain that is self-consistent with the uniquely illuminated intensity measurements.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: May 26, 2020
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Roarke W. Horstmeyer, Changhuei Yang
  • Patent number: 10652444
    Abstract: Certain embodiments pertain to Multiplexed Fourier Ptychographic imaging systems and methods. In one example, the Multiplexed Fourier Ptychographic imaging system includes an LED array configured to illuminate a sequence of LED patterns for illuminating a sample being imaged. The system includes LED circuitry configured to independently control power to turn on multiple LEDs simultaneously in each LED pattern of the array. The system has a light detector that acquires a first set of lower resolution images of the sample each image acquired during exposure time during illumination by a unique LED pattern. The system uses the first set of lower resolution images to generate a second set of lower resolution images associated with each LED in the LED array and iteratively updates overlapping regions in the Fourier domain with the second set of lower resolution images to generate a higher resolution image.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: May 12, 2020
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Roarke W. Horstmeyer, Guoan Zheng, Changhuei Yang
  • Patent number: 10606055
    Abstract: Certain aspects pertain to aperture-scanning Fourier ptychographic imaging devices comprising an aperture scanner that can generate an aperture at different locations at an intermediate plane of an optical arrangement, and a detector that can acquire lower resolution intensity images for different aperture locations, and wherein a higher resolution complex image may be constructed by iteratively updating regions in Fourier space with the acquired lower resolution images.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: March 31, 2020
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Roarke W. Horstmeyer, Guoan Zheng, Xiaoze Ou, Changhuei Yang
  • Patent number: 10419665
    Abstract: Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier ptychographic imaging systems.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: September 17, 2019
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Xiaoze Ou, Roarke W. Horstmeyer, Guoan Zheng, Changhuei Yang
  • Publication number: 20190056578
    Abstract: Certain aspects pertain to ptychographic imaging systems and methods with convex relaxation. In some aspects, a ptychographic imaging system with convex relaxation comprises one or more electromagnetic radiation sources, a digital radiation intensity detector, and a processor in communication with the digital radiation detector. The electromagnetic radiation provides coherent radiation to a specimen while the digital radiation intensity detector receives light transferred from the sample by diffractive optics and captures intensity distributions for a sequence of low resolution images having diversity. The processor generates a convex problem based on the sequence of low resolution images and optimizes the convex problem to reconstruct a high-resolution image of the specimen. In certain aspects, the convex problem is relaxed into a low-rank formulation.
    Type: Application
    Filed: October 25, 2018
    Publication date: February 21, 2019
    Inventors: Roarke W. Horstmeyer, Yuhua Chen, Joel A. Tropp, Changhuei Yang
  • Patent number: 10162161
    Abstract: Certain aspects pertain to ptychographic imaging systems and methods with convex relaxation. In some aspects, a ptychographic imaging system with convex relaxation comprises one or more electromagnetic radiation sources, a digital radiation intensity detector, and a processor in communication with the digital radiation detector. The electromagnetic radiation provides coherent radiation to a specimen while the digital radiation intensity detector receives light transferred from the sample by diffractive optics and captures intensity distributions for a sequence of low resolution images having diversity. The processor generates a convex problem based on the sequence of low resolution images and optimizes the convex problem to reconstruct a high-resolution image of the specimen. In certain aspects, the convex problem is relaxed into a low-rank formulation.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: December 25, 2018
    Assignee: California Institute of Technology
    Inventors: Roarke W. Horstmeyer, Yuhua Chen, Joel A. Tropp, Changhuei Yang
  • Publication number: 20180316855
    Abstract: Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier ptychographic imaging systems.
    Type: Application
    Filed: April 26, 2018
    Publication date: November 1, 2018
    Inventors: Xiaoze Ou, Roarke W. Horstmeyer, Guoan Zheng, Changhuei Yang
  • Publication number: 20180307017
    Abstract: Certain aspects pertain to aperture-scanning Fourier ptychographic imaging devices comprising an aperture scanner that can generate an aperture at different locations at an intermediate plane of an optical arrangement, and a detector that can acquire lower resolution intensity images for different aperture locations, and wherein a higher resolution complex image may be constructed by iteratively updating regions in Fourier space with the acquired lower resolution images.
    Type: Application
    Filed: April 20, 2018
    Publication date: October 25, 2018
    Inventors: Roarke W. Horstmeyer, Guoan Zheng, Xiaoze Ou, Changhuei Yang
  • Patent number: 9993149
    Abstract: Certain embodiments pertain to Fourier ptychographic retinal imaging methods and systems that focus on a retina of an eye to acquire a sequence of raw retinal images, construct a full-resolution, complex retinal image from the sequence of raw retinal image and correct the aberration in the full-resolution, complex retinal image to generate a substantially aberration-free retinal image.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: June 12, 2018
    Assignee: California Institute of Technology
    Inventors: Jaebum Chung, Roarke W. Horstmeyer, Changhuei Yang
  • Patent number: 9998658
    Abstract: Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier ptychographic imaging systems.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: June 12, 2018
    Assignee: California Institute of Technology
    Inventors: Xiaoze Ou, Roarke W. Horstmeyer, Guoan Zheng, Changhuei Yang
  • Patent number: 9983397
    Abstract: Certain aspects pertain to aperture-scanning Fourier ptychographic imaging devices comprising an aperture scanner that can generate an aperture at different locations at an intermediate plane of an optical arrangement, and a detector that can acquire lower resolution intensity images for different aperture locations, and wherein a higher resolution complex image may be constructed by iteratively updating regions in Fourier space with the acquired lower resolution images.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: May 29, 2018
    Assignee: California Institute of Technology
    Inventors: Roarke W. Horstmeyer, Guoan Zheng, Xiaoze Ou, Changhuei Yang
  • Publication number: 20170273551
    Abstract: Certain embodiments pertain to Fourier ptychographic retinal imaging methods and systems that focus on a retina of an eye to acquire a sequence of raw retinal images, construct a full-resolution, complex retinal image from the sequence of raw retinal image and correct the aberration in the full-resolution, complex retinal image to generate a substantially aberration-free retinal image.
    Type: Application
    Filed: March 25, 2016
    Publication date: September 28, 2017
    Inventors: Jaebum Chung, Roarke W. Horstmeyer, Changhuei Yang
  • Publication number: 20160320595
    Abstract: Certain aspects pertain to aperture-scanning Fourier ptychographic imaging devices comprising an aperture scanner that can generate an aperture at different locations at an intermediate plane of an optical arrangement, and a detector that can acquire lower resolution intensity images for different aperture locations, and wherein a higher resolution complex image may be constructed by iteratively updating regions in Fourier space with the acquired lower resolution images.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventors: Roarke W. Horstmeyer, Guoan Zheng, Xiaoze Ou, Changhuei Yang
  • Publication number: 20160320605
    Abstract: Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier ptychographic imaging systems.
    Type: Application
    Filed: July 13, 2016
    Publication date: November 3, 2016
    Inventors: Xiaoze Ou, Roarke W. Horstmeyer, Guoan Zheng, Changhuei Yang
  • Publication number: 20160210763
    Abstract: Certain aspects pertain to Fourier ptychographic tomographic systems and methods for acquiring a plurality of uniquely illuminated intensity measurements based on light passing through a thick sample from plane wave illumination at different angles and for constructing three-dimensional tomographic data of the thick sample by iteratively determining three-dimensional tomographic data in the Fourier domain that is self-consistent with the uniquely illuminated intensity measurements.
    Type: Application
    Filed: January 21, 2016
    Publication date: July 21, 2016
    Inventors: Roarke W. Horstmeyer, Changhuei Yang
  • Publication number: 20160178883
    Abstract: Certain aspects pertain to epi-illumination Fourier ptychographic imaging systems and methods for high resolution imaging of thick samples.
    Type: Application
    Filed: December 22, 2015
    Publication date: June 23, 2016
    Inventors: Roarke W. Horstmeyer, Changhuei Yang
  • Publication number: 20160088205
    Abstract: Certain embodiments pertain to Multiplexed Fourier Ptychographic imaging systems and methods. In one example, the Multiplexed Fourier Ptychographic imaging system includes an LED array configured to illuminate a sequence of LED patterns for illuminating a sample being imaged. The system includes LED circuitry configured to independently control power to turn on multiple LEDs simultaneously in each LED pattern of the array. The system has a light detector that acquires a first set of lower resolution images of the sample each image acquired during exposure time during illumination by a unique LED pattern. The system uses the first set of lower resolution images to generate a second set of lower resolution images associated with each LED in the LED array and iteratively updates overlapping regions in the Fourier domain with the second set of lower resolution images to generate a higher resolution image.
    Type: Application
    Filed: December 4, 2015
    Publication date: March 24, 2016
    Inventors: Roarke W. Horstmeyer, Guoan Zheng, Changhuei Yang
  • Publication number: 20150331228
    Abstract: Certain aspects pertain to ptychographic imaging systems and methods with convex relaxation. In some aspects, a ptychographic imaging system with convex relaxation comprises one or more electromagnetic radiation sources, a digital radiation intensity detector, and a processor in communication with the digital radiation detector. The electromagnetic radiation provides coherent radiation to a specimen while the digital radiation intensity detector receives light transferred from the sample by diffractive optics and captures intensity distributions for a sequence of low resolution images having diversity. The processor generates a convex problem based on the sequence of low resolution images and optimizes the convex problem to reconstruct a high-resolution image of the specimen. In certain aspects, the convex problem is relaxed into a low-rank formulation.
    Type: Application
    Filed: May 13, 2015
    Publication date: November 19, 2015
    Inventors: Roarke W. Horstmeyer, Yuhua Chen, Joel A. Tropp, Changhuei Yang