Patents by Inventor Rob CLARKSON

Rob CLARKSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6.alpha.-alkyl-6,7-dione steroids as intermediates for the production of steroidal FXR modulators
    Patent number: 10597423
    Abstract: Disclosed herein is a process for the preparation of a compound of formula (I) and related methods. The compounds of formula (I) are intermediates in the synthesis of synthetic bile acids and its analogues, and the compounds of formula (I) have pharmacological activity. Methods include the synthesizing of these intermediates, and methods of preparing obeticholic acid and obeticholic acid analogues from the prepared compounds.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: March 24, 2020
    Assignee: NZP UK Limited
    Inventors: Alexander Weymouth-Wilson, Zofia Komsta, James Boydell, Laura Wallis, Carl Otter, Ieuan Davies, Rob Clarkson
  • 6.Alpha.-Alkyl-6,7-Dione Steroids as Intermediates for the Production of Steroidal FXR Modulators
    Publication number: 20190077827
    Abstract: The invention relates to compounds of formula (I), wherein R1, R2, Y, R4 and R5b are as defined herein. The compounds are intermediates in the synthesis of synthetic bile acids.
    Type: Application
    Filed: October 17, 2018
    Publication date: March 14, 2019
    Applicant: NZP UK Limited
    Inventors: Alexander Weymouth-Wilson, Zofia Komsta, James Boydell, Laura Wallis, Carl Otter, Ieuan Davies, Rob Clarkson
  • 6.ALPHA.-ALKYL-6,7-DIONE STEROIDS AS INTERMEDIATES FOR THE PRODUCTION OF STEROIDAL FXR MODULATORS
    Publication number: 20170327531
    Abstract: The invention relates to compounds of formula (I), wherein R1, R2, Y, R4 and R5b are as defined herein. The compounds are intermediates in the synthesis of synthetic bile acids.
    Type: Application
    Filed: November 19, 2015
    Publication date: November 16, 2017
    Inventors: Alexander WEYMOUTH-WILSON, Zofia KOMSTA, James BOYDELL, Laura WALLIS, Carl OTTER, Ieuan DAVIES, Rob CLARKSON