Abstract: Disclosed herein are methods for treating or preventing ophthalmic and dermatologic conditions in a patient, including ocular surface conditions such as blepharitis. The methods can include topically administering directly to an ocular surface of one or more eyes of a patient in need of treatment thereof an effective amount of an isoxazoline parasiticide, formamidine parasiticide, or other active ingredient, formulated into an ophthalmic composition, the ophthalmic composition further comprising a pharmaceutically acceptable vehicle. Compositions are also disclosed.

Abstract: Disclosed herein are methods for treating or preventing ophthalmic and dermatologic conditions in a patient, including ocular surface conditions such as blepharitis. The methods can include topically administering directly to an ocular surface of one or more eyes of a patient in need of treatment thereof an effective amount of an isoxazoline parasiticide, formamidine parasiticide, or other active ingredient, formulated into an ophthalmic composition, the ophthalmic composition further comprising a pharmaceutically acceptable vehicle. Compositions are also disclosed.

Abstract: A cryogenic system includes a superconducting magnet (20) in a reservoir of liquid helium (LH). Helium vapor (VH) rises and contacts a recondenser surface (50, 50?, 50?) on which the helium vapor (VH) condenses into liquid helium and flows by gravity off a lower edge of the recondenser surface. A plurality of fins (52) extend from the recondenser surface or a plurality of grooves (52?, 52?) are cut into the recondenser surface to disrupt the film thickness and to provide a path by which droplets of the liquid helium leave the recondenser surface without travelling a full vertical length of the recondenser (30).

Abstract: When cooling a superconducting magnet for use in a magnetic resonance imaging (MRI) device, a two-stage cryocooler (42) employs a first stage cooler (52) to cool a working gas (e.g., Helium, Hydrogen, etc.) to approximately 25 K. The working gas moves through a tubing system by convection until the magnet (20) is at approximately 25K. Once the magnet (20) reaches 25 K, gas flow stops, and a second stage cooler (54) cools the magnet (20) further, to about 4 K.

Abstract: When cooling a superconducting magnet for use in a magnetic resonance imaging (MRI) device, a two-stage cryocooler (42) employs a first stage cooler (52) to cool a working gas (e.g., Helium, Hydrogen, etc.) to approximately 25 K. The working gas moves through a tubing system by convection until the magnet (20) is at approximately 25K. Once the magnet (20) reaches 25 K, gas flow stops, and a second stage cooler (54) cools the magnet (20) further, to about 4 K.

Abstract: A cryogenic system includes a superconducting magnet (20) in a reservoir of liquid helium (LH). Helium vapor (VH) rises and contacts a recondenser surface (50, 50?, 50?) on which the helium vapor (VH) condenses into liquid helium and flows by gravity off a lower edge of the recondenser surface. A plurality of fins (52) extend from the recondenser surface or a plurality of grooves (52?, 52?) are cut into the recondenser surface to disrupt the film thickness and to provide a path by which droplets of the liquid helium leave the recondenser surface without travelling a full vertical length of the recondenser (30).

Abstract: A system can include a heat transfer structure and a heat exchanger. The heat transfer structure is to cool an object, and the heat exchanger is to cool a portion of the heat transfer structure. The system can be cooled significantly faster than a conventional system that uses conductive cooling. The system has no or less liquid cryogen that would be vaporized as compared to a conventional system that immerses the object to be cooled within a bath of liquid cryogen or has a substantial mass of liquid cryogen within a cooling loop.

Abstract: A method for calculating a mass flow rate of a cryogenic fluid within a flow tube includes positioning a sensor within a stream of cryogenic fluid flowing through the flow tube. The sensor is operatively coupled to a strain gauge. A difference between a dynamic pressure in the fluid stream and a static pressure in the fluid stream is measured and the mass flow rate of the cryogenic fluid within the flow tube is calculated.

Abstract: A cooling system for providing cryogenic cooling fluid to an apparatus comprises a re-circulation device, a passive cold storage device having a porous matrix of material which directly contacts the cryogenic cooling fluid as the cryogenic cooling fluid passes through the passive cold storage device, a first portion of a fluid communication feed line fluidly connecting the re-circulation device to the passive cold storage device, a second portion of a fluid communication feed line fluidly connecting the passive cold storage device to the apparatus for communicating cryogenic cooling fluid to the apparatus, and a fluid communication return line fluidly connecting the apparatus to the re-circulation device. The passive cold storage device may comprise a regenerative heat exchanger including a porous matrix of metal wire mesh, metal spheres or ceramic spheres.

Abstract: A stackable and nestable container having a bottom surface, a first pair of opposed end walls integrally joined with the bottom surface and extending upwardly away therefrom, and a second pair of opposed side walls integrally joined with the bottom surface and extending upwardly away therefrom. The first and second pairs of opposed end walls and side walls are integrally joined with each other along common end surfaces thereof to form with the bottom surface a substantially rectangular open top container. Each of the end walls and side walls includes a pair of column sections, and each of the column sections includes a recessed portion, an inner shelf and a lower column support. Each of the end walls and side walls further includes a pair of stacking sections, and each of the stacking sections includes a stacking foot and a stacking shelf.

Abstract: A superconductive lead assembly for a superconductive device (e.g., magnet) cooled by a cryocooler coldhead having first and second stages. A first ceramic superconductive lead has a first end flexibly, dielectrically, and thermally connected to the first stage and a second end flexibly, dielectrically, and thermally connected to the second stage. A jacket of open cell material (e.g., polystyrene foam) is in general surrounding compressive contact with the first ceramic superconductive lead, and a rigid support tube generally surrounds the jacket. This protects the first ceramic superconductive lead against shock and vibration while in the device. The rigid support tube has a first end and a second end, with the second end thermally connectable to the second stage.

Abstract: A superconductive lead assembly for a superconductive device (e.g., magnet) cooled by a cryocooler coldhead having first and second stages. A first ceramic superconductive lead has a first end flexibly, dielectrically, and thermally connected to the first stage and a second end flexibly, dielectrically, and thermally connected to the second stage. A jacket of open cell material (e.g., polystyrene foam) is in general surrounding compressive contact with the first ceramic superconductive lead, and a rigid support tube generally surrounds the jacket. This protects the first ceramic superconductive lead against shock and vibration while in the device. The rigid support tube has a first end and a second end, with the second end thermally connectable to the second stage.

Abstract: An open magnetic resonance imaging (MRI) magnet having longitudinally spaced-apart superconductive main coils surrounded by a dewar containing a cryogenic liquid (e.g., liquid helium) and boiled-off cryogenic gas (e.g., helium vapor). A condenser is in physical contact with the boiled-off vapor and is in thermal contact with a cold stage of a cryocooler coldhead so as to re-liquefy the vapor. This allows the coils to be surrounded by a single (not double) thermal shield which allows the coils structurally to be located closer to the magnet's open space which reduces magnet cost by reducing the amount of coil needed for the same-strength magnetic field.

Abstract: A superconductive lead assembly for a superconductive device (e.g., magnet) cooled by a cryocooler coldhead having first and second stages. A first ceramic superconductive lead has a first end flexibly, dielectrically, and thermally connected to the first stage and a second end flexibly, dielectrically, and thermally connected to the second stage. A jacket of open cell material (e.g., polystyrene foam) is in general surrounding compressive contact with the first ceramic superconductive lead, and a rigid support tube generally surrounds the jacket. This protects the first ceramic superconductive lead against shock and vibration while in the device. The rigid support tube has a first end and a second end, with the second end thermally connectable to the second stage.

Abstract: A superconductive lead assembly for a superconductive device (e.g., magnet) cooled by a cryocooler coldhead having first and second stages. A first ceramic superconductive lead has a first end flexibly, dielectrically, and thermally connected to the first stage and a second end flexibly, dielectrically, and thermally connected to the second stage. A jacket of open cell material (e.g., polystyrene foam) is in general surrounding compressive contact with the first ceramic superconductive lead, and a rigid support tube generally surrounds the jacket. This protects the first ceramic superconductive lead against shock and vibration while in the device. The rigid support tube has a first end and a second end, with the second end thermally connectable to the second stage.

Abstract: A cryogenic cooling system includes a cryocooler coldhead having a cold stage. A gas circulator has a low pressure input orifice and a high pressure output orifice, and a valve has a primary port and a secondary port. The valve makes and switches fluid connections between the valve's primary and secondary ports and the gas circulator's input and output orifices. A heat exchanger has a primary portion and a secondary portion each in thermal contact with the cold stage. The primary (secondary) regenerator is positioned between the primary (secondary) port of the valve and the primary (secondary) portion of the heat exchanger. A coolant flow path has a first end in fluid communication with the heat exchanger's primary portion and a second end in fluid communication with the heat exchanger's secondary portion. The coolant flow path may be placed in thermal contact with a superconductive device.

Abstract: A superconductive magnet having a superconductive coil located within a thermal shield located within a vacuum enclosure. A cryocooler coldhead's first stage is in solid-conductive thermal contact with the thermal shield, and its second stage is in solid-conductive thermal contact with the superconductive coil. A magnet re-entrant support assembly includes an outer support cylinder located between the vacuum enclosure and the thermal shield and includes an inner support cylinder located between the thermal shield and the superconductive coil. The outer support cylinder's first end is rigidly connected to the vacuum enclosure, and its second end is rigidly connected to the thermal shield. The inner support cylinder's first terminus is rigidly connected to the thermal shield near the outer support cylinder's second end, and its second terminus is located longitudinally between the outer support cylinder's first and second ends and is rigidly connected to the superconductive coil.

Abstract: This invention relates to linear motor compressors which operate without the use of oil. Such structures of this type, generally, provide a highly reliable oil-free compressor for use with cryogenic refrigeration equipment so as to attain unattended, continuous operation without maintenance over extended periods of time.

Abstract: Materials for cryogenic refrigerator regenerators are formed by a high yield spark erosion cell. The materials are made of erbium or dysprosium and are spherical shaped. The spheres have a diameter range of 150 .mu.m to 400 .mu.m with a packing factor of at least 50%. The materials are made by disposing chunks of a starting material into a liquid dielectric in a spark chamber, agitating the chunks, impressing a spark voltage in order to cause melting of the chunks and formation of spherical particles, and collecting the particles at the bottom of the spark chamber. The particles may then be gathered, dried, and separated.