Abstract: The invention provides a perfusion stock composition, for preserving a donor organ for transplantation, comprising: a source of 60 to 100 mM Na+; a source of 10 to 20 mM K+; a source of 5 to 10 mM Mg2+; a source of 0.25 to 0.75 mM Ca 2+; 10 to 40 mM Tris(hydroxymethyl)aminomethane hydrochloride (Tris or THAM), 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), 3-(N-morpholino)propanesulfonic acid (MOPS), 2-(N-mo:rpholino)ethanesulfonic acid (IviES), NjN-bis-(2-hy-droxyethyl)-2-aminoethansulfonic acid (BES), or N/-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid (TES); a source of 10 to 30 mM HC03?; 1 to 30 mM glucose; 1 to 20 U/L insulin; 1 to 10 mM fructose diphosphate or a salt thereof; 1 to 40 mM aspartate or glutamate; 1 to 10 mM adenosine, cAMP or cGMP; 1 to 10 mM reduced glutathione; and 30 to 100 mM lactobionate or mamlitol; and optionally a diluent.

Abstract: A perfusion stock composition, for preserving a donor organ for transplantation, comprising: a source of 60 to 100 mM Na+; a source of 10 to 20 mM K+; a source of 5 to 10 mM Mg2+; a source of 0.25 to 0.75 mM Ca2+; 10 to 40 mM Tris(hydroxymethyl)aminomethane hydrochloride (Tris or THAM), 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), 3-(N-morpholino)propanesulfonic acid (MOPS), 2-(N-morpholino)ethanesulfonic acid (IviES), N,N-bis-(2-hydroxyethyl)-2-aminoethanesulfonic acid (BES), or N/-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid (TES); a source of 10 to 30 mM HCO3; 1 to 30 mM glucose; 1 to 20 U/L insulin; 1 to 10 mM fructose diphosphate or a salt thereof; 1 to 40 mM aspartate or glutamate; 1 to 10 mM adenosine, cAMP or cGMP; 1 to 10 mM reduced glutathione; and 30 to 100 mM lactobionate or mannitol; and, optionally, a diluent. The present disclosure also provides a perfusion composition, a kit, a method, and a perfusion apparatus, each related to the perfusion stock composition.

Abstract: Provided herein are compounds or pharmaceutically acceptable salts thereof, having a structure of formula (I): wherein substituents are as described herein. Also provided is a pharmaceutical composition comprising a compound or pharmaceutically acceptable salt having a structure of formula (I). Further provided are a method of inhibiting cyclin dependent kinase 19 (CDK19) a method of treating cancer (e.g., breast cancer) with the disclosed compounds.

Abstract: A system and method for displaying advertisements to a viewer. An advertiser may upload one or more advertisements to a server and select various parameters for displaying the advertisement to a viewer. A viewer may choose to view advertisements in return for compensation. The viewer may be asked to verify comprehension or provide feedback on the advertisements before compensation is awarded.

Abstract: The present disclosure relates to a device for generating vertical force. The device includes a housing, at least one bearing sleeve mounted in the housing, and at least one mass sleeve mounted within the bearing sleeve. The mass sleeve includes first and second masses with the first mass being larger than the second mass and the first and second masses being positioned substantially 180 degrees relative to one another. Related methods are described.

Abstract: The present disclosure relates to a device for generating vertical force. The device includes a housing, at least one bearing sleeve mounted in the housing, and at least one mass sleeve mounted within the bearing sleeve. The mass sleeve includes first and second masses with the first mass being larger than the second mass and the first and second masses being positioned substantially 180 degrees relative to one another. Related methods are described.

Abstract: Disclosed is a system and method for providing concealed information to users. The system may include a dispensing terminal, which dispenses specially-printed documents having removable window or lens devices disposed on them. The user may remove the window or lens device to reveal the concealed information, which may include promotional information. The concealed information may be included on the specially-printed documents or on a surface of the window or lens device. When the concealed information is on the surface of the window or lens device, a display may be used to reveal the information.

Abstract: Disclosed is a system and method for providing promotional information to potential customers. The system includes a dispensing terminal, which dispenses receipts that have game piece surfaces disposed on them. The customer may remove the game piece to reveal promotional information, including prizes or prize information may be revealed to the customer once he has viewed a website. The promotional information may include a website, through which the customer may log on or visit to see if he/she has won a prize. The website may provide additional promotional information to the customer, some of which may be provided by multiple promotion providers. In a variation of the system, the game piece surface conceals information encouraging the customer use his/her cell phone to send a text message to a specified number, along with a response to the promotional information. The system receives the text message and compares the entry code with codes that correspond to a winning entry.

Abstract: A method for interconnecting tubulars by forge welding involves arranging the tubular ends that are to be interconnected at a distance, up to a few millimeters from each other in a shield gas chamber, into which a reducing non-explosive flushing fluid mixture (e.g. N2+H2) is injected; heating each tubular end within the space by means of at least three electrodes that are pressed at circumferentially spaced intervals against the wall of each tubular, adjacent to the tubular end such that a high frequency electrical current is transmitted in a substantially circumferential direction through the tubular segments between the electrodes; and moving the thus uniformly heated tubular ends towards each other until a forge weld is formed between the heated tubular ends.

Abstract: Film faced expanded polystyrene foam board is prepared by heat laminating expanded polystyrene board with a film composition comprising a high density polyethylene film layer and a heat activated low density adhesive film layer. This board is useful in the construction industry.