Abstract: The invention also relates to antigen binding proteins and related fragments thereof for binding Von Willebrand factor (VWF) and uses thereof. In one aspect, the present invention provides an antigen binding protein comprising an antigen binding domain that binds to or specifically binds to Von Willebrand factor (VWF) under shear gradient conditions. Preferably, the antigen binding protein comprises an antigen binding domain that does not bind to VWF under constant shear conditions.

Abstract: Auxiliary power connector PCBs are described. In one example, an auxiliary power connector is described. The auxiliary power connector includes a printed circuit board (PCB) and a PCI express graphics (PEG) connector mounted to the PCB, the PEG connector configured to connect to an auxiliary power source. The auxiliary power connector further includes a set of connectors provided on the PCB, the set of connectors configured to connect the PCB to a main PCB of a device.

Abstract: Techniques are disclosed relating to monitoring network traffic of an embeddable browser displayed by an application executing on a mobile computing device. In some embodiments, a first layer of the application manipulates one or more user interface elements displayed in the embeddable browser. The first layer of the application then detects network requests made by one or more application programming interfaces (APIs) executed by the embeddable browser in response to the manipulating. In some embodiments, the first layer sends to a second layer of the application results of observing network requests. In some embodiments, the second layer of the application displays, in real-time, information corresponding to the results of observing network requests.

Abstract: In one embodiment, an apparatus for docking vehicles includes a housing structure comprising two side portions and a top portion connecting the two side portions, the two side portions and the top portion forming a cavity for receiving a portion of a vehicle, an electrically-powered locking assembly, carried by the housing structure, for securing the housing structure to the vehicle in response to the portion of the vehicle being received by the cavity of the housing structure, an electrically-powered communication device, coupled to the housing structure, for enabling data communication over a network, and a solar panel, carried by an external surface of one of the side portions of the housing structure, for independently converting light received by the solar panel into electrical energy.

Abstract: A network device is configured to (i) play back a media item indicated by a remote playback queue provided by a cloud-based computing system, (ii) receive an indication that a playback device is available for playback, (iii) display a now playing screen including (a) information identifying the media item, and (b) an icon that indicates that the network device is not in a connected state with any other network device, (iv) receive a first input selecting the icon, (v) in response to the first input, display a list of one or more available network devices including the playback device, (vi) receive a second input selecting the playback device from the list (vii) after receiving the second input, update the list to indicate that the playback device is selected for playback of the remote playback queue, and (viii) transfer playback of the remote playback queue from the network device to the playback device.

Abstract: Apparatus having at least one breakout structure are provided. In one example, an apparatus includes a dielectric layer, first and second contact pads, and first and second vias. The first and second contact pads are disposed on the dielectric layer. The first via is disposed through the dielectric layer and coupled to the first contact pad. The first via is offset from the first contact pad in a first direction. The second contact pad is immediately adjacent the first via. The second via is disposed through the dielectric layer immediately adjacent the first contact pad and coupled to the second contact pad. The second via is offset from the second contact pad in a second direction that is opposite of the first direction. The first and the second contact pads define a first differential pair of contact pads that is configured to transmit a first differential pair of signals.

Abstract: The present disclosure relates generally to compositions and methods for modulating signal transduction mediated by interleukin-10 (IL-10). In particular, the disclosure provides novel IL-10 polypeptide variants with altered binding affinity to interleukin-10 receptor subunit beta (IL-10R?). Also provided are compositions and methods useful for producing such IL-10 polypeptide variants, as well as methods for modulating IL-10-mediated signaling, and/or for the treatment of conditions associated with the perturbation of signal transduction mediated by IL-10.

Abstract: The present disclosure relates generally to compositions and methods for modulating signal transduction mediated by interleukin-22 (IL-22). In particular, the disclosure provides novel IL-22 polypeptide variants with altered binding affinity to interleukin-10 receptor subunit beta (IL-10R?). Also provided are compositions and methods useful for producing such IL-22 polypeptide variants, as well as methods for modulating IL-22-mediated signaling, and/or for the treatment of conditions associated with the perturbation of signal transduction mediated by IL-22.

Abstract: A method for remote monitoring of an industrial machine having a relay based or PLC based controller includes steps of providing a hardware interface module for directly interfacing with the relay based or PLC based controller of the industrial machine, directly interfacing the hardware interface module with the relay based or PLC based controller to identify occurrence of power cycles of the industrial machine, registering the hardware interface module through a portal accessible through a network, communicating the occurrence of the power cycles of the industrial machine detected with the hardware interface module to a database in operative communication with the portal and storing the occurrence of the power cycles within the database, and providing a user interface indicative of performance of the industrial machine based on the power cycles of the industrial machine detected with the hardware interface module and stored in the database.

Abstract: Systems, devices, and methods for a two wire detection circuit powered system comprising: an electronic switch circuit configured to sense a pressure level above or below a predetermined value and indicate an open or closed switch condition, where the electronic switch circuit provides a contact resistance voltage of about 20 mV in the closed switch condition; and an energy harvester configured to convert 20 mV when the electronic switch circuit is in the closed switch condition to an operating voltage between 3.6 Volts and 5 Volts for the electronic switch circuit to operate without an additional power source.

Abstract: User traffic is processed in a virtualised network. First and second VNFs are initialised in the same network namespace as each other in user space in a host and have access to a shared memory region of the host. The first VNF processes user traffic and the second VNF provides a user plane service in relation to user traffic processed by the first VNF. The first VNF is used to establish a point-to-point, shared-memory interface between the first and second VNFs and is used to classify incoming user traffic. In response to the first VNF determining based on the classifying, that the incoming user traffic is to be subject to the user plane service, the first VNF is used to store the incoming user traffic in the shared memory region of the host to enable the second VNF to provide the user plane service in relation to the incoming trier traffic.

Abstract: A method of providing a frame-based mel spectral representation of speech includes receiving a text utterance having at least one word and selecting a mel spectral embedding for the text utterance. Each word has at least one syllable and each syllable has at least one phoneme. For each phoneme, the method further includes using the selected mel spectral embedding to: (i) predict a duration of the corresponding phoneme based on corresponding linguistic features associated with the word that includes the corresponding phoneme and corresponding linguistic features associated with the syllable that includes the corresponding phoneme; and (ii) generate a plurality of fixed-length predicted mel-frequency spectrogram frames based on the predicted duration for the corresponding phoneme. Each fixed-length predicted mel-frequency spectrogram frame represents mel-spectral information of the corresponding phoneme.

Abstract: A system and method are described for depositing a material onto a receiving surface, where the material is formed by use of a plasma to modify a source material in-transit to the receiving surface. The system comprises a microwave generator electronics stage. The system further includes a microwave applicator stage including a cavity resonator structure. The cavity resonator structure includes an outer conductor, an inner conductor, and a resonator cavity interposed between the outer conductor and the inner conductor. The system also includes a multi-component flow assembly including a laminar flow nozzle providing a shield gas, a zonal flow nozzle providing a functional process gas, and a source material flow nozzle configured to deliver the source material. The source material flow nozzle and zonal flow nozzle facilitate a reaction between the source material and the functional process gas within a plasma region.

Abstract: A method to treat epilepsy through administering a pharmaceutical composition comprising cannabidiol (CBD) and ?9-tetrahydrocannabinol (THC) to the subject, wherein the ratio of CBD to THC in the pharmaceutical composition is between about 5:1 and about 1:1

Abstract: An ultrasonic device for scanning an object, the device having a collar configured for coupling to the object, the collar having an arcuate segment, a carriage coupled to the collar, the carriage configured for displacement along the arcuate segment, a ultrasonic probe unit coupled to the collar and comprising a wedge having a contoured face configured for maintaining conforming contact against a surface of the object, the ultrasonic probe unit configured to emit an ultrasonic beam for transmission through the contoured face of the wedge and into the object, and a position locator coupled to the carriage, the position locator configured to record a position of the ultrasonic probe unit.

Abstract: A self-checkout system can include a plurality of telescoped bagging arm segments moveably coupled together in an order according to respective diameters of the plurality of telescoped bagging arm segments. A scanning system can be configured to provide a characteristic of an item purchased by a user of the self-checkout system and a processor circuit can be operatively coupled to the plurality of telescoped bagging arm segments and to the scanning system, where the processor circuit can be configured to move the plurality of telescoped bagging arm segments relative to one another based on the characteristic of the item to be placed in a bag in use with the self-checkout system.

Abstract: Some implementations provide a method that includes: generating an association, at a mobile device, between a government-issued identification document of a user and a mode of payment; receiving, at the mobile device, a presentation of the government-issued identification document of the user to support a request for payment; validating whether the presented government-issued identification document is a valid identification of the user; and in response to validating the presented government-issued identification document, proceeding with payment by using the mode of payment.

Abstract: Methods for activating and expanding TILs using unconventional cytokines are provided. These methods include techniques for activating and expanding TILs using streamlined approaches, including one-step approaches, approaches using agonists for stimulation, approaches more suitable for clinical manufacturing, and approaches without the requirement of feeder cells, are provided. Compositions of expanded populations of TILs are also provided, in addition to populations of expanded TILs enriched in central memory T cell phenotype.