Patents by Inventor Robert A. Ashley

Robert A. Ashley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190091244
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Application
    Filed: August 1, 2018
    Publication date: March 28, 2019
    Applicant: GALDERMA LABORATORIES, INC.
    Inventor: Robert A. ASHLEY
  • Patent number: 10058564
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: August 28, 2018
    Assignee: Galderma Laboratories Inc.
    Inventor: Robert A. Ashley
  • Publication number: 20180185448
    Abstract: The present invention relates generally to metabolic detoxification, and more particularly to a composition and method for inducing an anti-inflammatory response in a cell, as well as treating disease in a subject.
    Type: Application
    Filed: June 14, 2016
    Publication date: July 5, 2018
    Inventor: Robert A. Ashley
  • Publication number: 20180185446
    Abstract: The present invention provides a composition and method for inducing anti-apoptosis, anti-pyroptosis, anti-necroptosis, survival, protection, proliferation, and/or phenotypic modulation of a cell, as well as treating disease in a subject.
    Type: Application
    Filed: June 14, 2016
    Publication date: July 5, 2018
    Inventors: Robert A. Ashley, Lee Landeen
  • Publication number: 20160136188
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Application
    Filed: January 22, 2016
    Publication date: May 19, 2016
    Inventor: Robert A. Ashley
  • Patent number: 9241946
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: January 26, 2016
    Assignee: GALDERMA LABORATORIES INC.
    Inventor: Robert A. Ashley
  • Publication number: 20150297618
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Application
    Filed: June 29, 2015
    Publication date: October 22, 2015
    Inventor: Robert A. Ashley
  • Publication number: 20140100200
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: Galderma Laboratories, Inc.
    Inventor: Robert A. Ashley
  • Patent number: 8658189
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: February 25, 2014
    Assignee: Galderma Laboratories, Inc.
    Inventor: Robert A. Ashley
  • Patent number: 8603506
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: December 10, 2013
    Assignee: Galderma Laboratories, Inc.
    Inventor: Robert A. Ashley
  • Publication number: 20120220555
    Abstract: A method for simultaneously treating ocular rosacea and acne rosacea in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat ocular rosacea and acne rosacea but has substantially no antibiotic activity.
    Type: Application
    Filed: May 7, 2012
    Publication date: August 30, 2012
    Applicant: GALDERMA LABORATORIES, INC.
    Inventor: Robert A. Ashley
  • Patent number: 8192749
    Abstract: A method for simultaneously treating ocular rosacea and acne rosacea in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat ocular rosacea and acne rosacea but has substantially no antibiotic activity.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: June 5, 2012
    Assignee: Galderma Laboratories Inc.
    Inventor: Robert A. Ashley
  • Publication number: 20120108552
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Application
    Filed: October 20, 2011
    Publication date: May 3, 2012
    Applicant: GALDERMA LABORATORIES, INC.
    Inventor: Robert A. Ashley
  • Patent number: 8052983
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: November 8, 2011
    Assignee: Galderma Laboratories, Inc.
    Inventor: Robert A. Ashley
  • Publication number: 20110262542
    Abstract: A composition is provided for delivering a tetracycline compound to a mammal. The composition includes an antibiotic tetracycline compound and a controlled-release agent having at least one controlled-release agent. The tetracycline compound is associated with the controlled-release matrix to provide a release profile whereby the mammal is treated substantially without antibiotic activity. Methods for treating a mammal with a tetracycline compound and a dosage unit are also provided utilizing the controlled-release tetracycline composition.
    Type: Application
    Filed: July 6, 2011
    Publication date: October 27, 2011
    Applicant: GALDERMA LABORATORIES INC.
    Inventor: Robert A. Ashley
  • Publication number: 20080171727
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Application
    Filed: October 22, 2007
    Publication date: July 17, 2008
    Inventor: Robert A. Ashley
  • Patent number: 7232572
    Abstract: A method of treating rosacea in a human in need thereof comprising administering to said human a tetracycline compound in an amount that is effective to treat rosacea, but has substantially no antibiotic activity.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: June 19, 2007
    Assignee: CollaGenex Pharmaceuticals, Inc.
    Inventor: Robert A. Ashley
  • Patent number: 7211267
    Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.
    Type: Grant
    Filed: April 5, 2002
    Date of Patent: May 1, 2007
    Assignee: CollaGenex Pharmaceuticals, Inc.
    Inventor: Robert A. Ashley
  • Patent number: 7014858
    Abstract: A method of treating telangiectasia in a human in need thereof comprising administering to said human a tetracycline compound in an amount that is effective to treat telangiectasia, but has substantially no antibiotic activity.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: March 21, 2006
    Assignee: CollaGenex Pharmaceuticals, Inc.
    Inventor: Robert A. Ashley
  • Patent number: 7008631
    Abstract: A method for simultaneously treating ocular rosacea and acne rosacea in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat ocular rosacea and acne rosacea but has substantially no antibiotic activity.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: March 7, 2006
    Assignee: CollaGenex Pharmaceuticals, Inc.
    Inventor: Robert A. Ashley