Patents by Inventor Robert A. Bosselman

Robert A. Bosselman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stem cell factor
    Publication number: 20080305074
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Application
    Filed: February 5, 2007
    Publication date: December 11, 2008
    Applicant: AMGEN INC.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Stem cell factor
    Publication number: 20070071714
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Application
    Filed: September 7, 2006
    Publication date: March 29, 2007
    Applicant: AMGEN INC.
    Inventors: Krisztina Zsebo, Robert Bosselman, Sidney Suggs, Francis Martin
  • SCF antibody compositions and methods of using the same
    Patent number: 7144731
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: December 5, 2006
    Assignee: Amgen Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • SCF antibody compositions and methods of using the same
    Publication number: 20050261175
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Application
    Filed: January 28, 2003
    Publication date: November 24, 2005
    Inventors: Krisztina Zsebo, Robert Bosselman, Sidney Suggs, Francis Martin
  • Method for increasing hematopoietic progenitor cells by stem cell factor
    Patent number: 6967029
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: November 22, 2005
    Assignee: Amgen Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Methods of stimulating growth of stromal cells in a human
    Publication number: 20050080250
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Application
    Filed: July 16, 2003
    Publication date: April 14, 2005
    Inventors: Krisztina Zsebo, Robert Bosselman, Sidney Suggs, Francis Martin
  • Method of stimulating growth of melanocyte cells by administering stem cell factor
    Patent number: 6852313
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: February 8, 2005
    Assignee: Amgen Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Stem cell factor compositions
    Patent number: 6841147
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: January 11, 2005
    Assignee: Amgen, Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Method of stimulating growth of epithelial cells by administering stem cell factor
    Publication number: 20040181044
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Application
    Filed: June 19, 2002
    Publication date: September 16, 2004
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Method of preparing human stem cell factor polypeptide
    Patent number: 6759215
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: July 6, 2004
    Assignee: Amgen Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • STEM CELL FACTOR: COMPOSITION CLAIMS
    Publication number: 20020031491
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Application
    Filed: December 31, 1998
    Publication date: March 14, 2002
    Inventors: KRISZKINA M. ZSEBO, ROBERT A. BOSSELMAN, SIDNEY V. SUGGS, FRANCIS H. MARTIN
  • A METHOD OF STIMULATING GROWTH OF STROMAL CELLS WITH STEM CELL FACTOR (SCF) POLYPEPTIDES
    Publication number: 20020018763
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Application
    Filed: January 12, 1998
    Publication date: February 14, 2002
    Inventors: KRISZKINA M. ZSEBO, ROBERT A. BOSSELMAN, SIDNEY V. SUGGS, FRANCIS H. MARTIN
  • Method for increasing hematopoietic progenitor cells by stem cell factor polypeptides
    Patent number: 6248319
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: June 19, 2001
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • DNS encoding stem cell factor
    Patent number: 6218148
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: December 21, 1993
    Date of Patent: April 17, 2001
    Assignee: Amgen Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Method for enhancing the effciency of gene transfer with stem cell factor (SCF) polypeptide
    Patent number: 6207454
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: March 27, 2001
    Assignee: Amgen Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • DNA encoding stem cell factor
    Patent number: 6207417
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 27, 2001
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Stem cell factor and compositions
    Patent number: 6207802
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: March 27, 2001
    Assignee: Amgen Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Stem cell factor
    Patent number: 6204363
    Abstract: Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also disclosed.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: March 20, 2001
    Assignee: Amgen Inc.
    Inventors: Krisztina M. Zsebo, Robert A. Bosselman, Sidney V. Suggs, Francis H. Martin
  • Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
    Patent number: 5795569
    Abstract: Disclosed are novel proteins, referred to as megakaryocyte growth and development factors (MGDFs; also generally referred to as Mpl ligands or thrombopoietin, that have a biological activity of stimulating the growth of megakaryocytes and augmenting the differentiation or maturation of megakaryocytes, ultimately to result in the production of platelets. MGDF derivatives comprising MGDF molecules attached to water soluble polymers, such as polyethylene glycol, are also disclosed, along with methods for their preparation. Also disclosed are processes for obtaining the MGDFs in homogeneous form from natural sources and producing them by recombinant genetic engineering techniques from mammals, including humans.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: August 18, 1998
    Assignee: Amgen Inc.
    Inventors: Timothy D. Bartley, Jakob M. Bogenberger, Robert A. Bosselman, Pamela Hunt, Olaf B. Kinstler, Babru B. Samal
  • Method for treating mammals with monopegylated proteins that stimulates megakaryocyte growth and differentiation
    Patent number: 5766581
    Abstract: Disclosed are novel proteins, referred to as megakaryocyte growth and development factors (MGDFs; also generally referred to as Mpl ligands), that have a biological activity of stimulating the growth of megakaryocytes and augmenting the differentiation or maturation of megakaryocytes, ultimately to result in the production of platelets. MGDF derivatives comprising MGDF molecules attached to water soluble polymers, such as polyethylene glycol, are also disclosed, along with methods for their preparation. The MGDF proteins and derivatives are useful in methods for treating mammals to increase platelets and/or megakaryocytes. Also disclosed are processes for obtaining the MGDFs in homogeneous form from natural sources and producing them by recombinant genetic engineering techniques from mammals, including humans.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: June 16, 1998
    Assignee: Amgen Inc.
    Inventors: Timothy D. Bartley, Jakob M. Bogenberger, Robert A. Bosselman, Pamela Hunt, Olaf B. Kinstler, Babru B. Samal