Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

Abstract: Techniques regarding microfluidic chips with one or more vias filled with sacrificial plugs and/or manufacturing methods thereof are provided herein. For example, one or more embodiments described herein can comprise an apparatus, which can comprise a silicon device layer of a microfluidic chip comprising a plurality of vias extending through the silicon device layer. The plurality of vias comprise greater than or equal to about 100 vias per square centimeter of a surface of the silicon device layer and less than or equal to about 100,000 vias per square centimeter of the surface of the silicon device layer. Additionally, the apparatus can comprise a plurality of sacrificial plugs positioned in the plurality of vias.

Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

Abstract: A method and a system of deploying an ignition interlock device (IID). The method comprises receiving a time series of breath alcohol content (BrAC) measurements that are unitarily sourced from a pre-identified user, each BrAC measurement of the time series including an alveolar breath component and an interferent breath component; estimating a dissipation rate of alcohol attributable to the pre-identified user in accordance with the time series of BrAC measurements; determining, responsive to estimating the dissipation rate of alcohol, at least a subset of the BrAC measurements as being based on the alveolar breath component but not the interferent breath component; and performing one of triggering and not triggering the IID into a lockout state based on the at least a subset of the BrAC measurements.

Abstract: The present disclosure provides topical compositions of rofecoxib and methods of making said compositions. The present disclosure also provides methods of using topical compositions of rofecoxib to treat inflammation.

Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

Abstract: Disclosed is a Designer Receptor Exclusively Activated by Designer Drugs (DREADD), and an amino acid sequence for determining coupling or no coupling between G-protein and G-protein coupled receptor (GPCR) mediated by a GPCR ligand in a cell based assay.

Abstract: A method of applying a neural stimulus with an implanted electrode array involves applying a sequence of stimuli configured to yield a therapeutic effect while suppressing psychophysical side effects. The stimuli sequence is configured such that a first stimulus recruits a portion of the fibre population, and a second stimulus is delivered within the refractory period following the first stimulus and the second stimulus being configured to recruit a further portion of the fibre population. Using an electrode array and suitable relative timing of the stimuli, ascending or descending volleys of evoked responses can be selectively synchronised or desynchronised to give directional control over responses evoked.

Abstract: An example computer-implemented method embodying the disclosed technology comprises digitally storing a plurality of digital objects comprising first type digital objects and second type digital objects, each digital object comprising an electronic digital representation of natural language text, and certain first type digital objects each being associated with exactly one second type digital object; programmatically generating a corpus of digital documents from the plurality of digital objects; programmatically embedding the electronic digital representation of natural language text of each first type digital object not associated with one of the second type digital objects, thereby generating a second set of vectors; programmatically determining, for each of the second set of vectors, a corresponding set of nearest neighbor vectors from the first set of vectors; programmatically generating recommendation data indicating potential new associations between first type digital objects and second type digital ob

Abstract: A system includes an antenna of a ground station. The antenna is configured to generate signal beams. The signal beams define a plurality of cells in the sky. The antenna is fixed in position relative to the ground and mechanically fixed to a particular orientation. The antenna is a phased array antenna. The system also includes a processor coupled to the antenna. The processor is configured to support concurrent communication sessions with a plurality of spacecraft via the signal beams. The plurality of spacecraft is located within the plurality of cells.

Abstract: A method of manufacturing for finishing ceramic core flash. Locating a first hole on a ceramic core by a laser sensor on a robot. Probing for a center of the first hole by a force-torque sensor on the robot. Scanning for an axial position of a second hole on the ceramic core. Scanning for a third hole on the ceramic core. Probing for a center of the third hole. Determining axial and radial scale factors based on the first hole location and the third hole location. Uploading the axial and radial scale factors to the robot Multiplying the X component position by the axial scale factor and the Z component position by the radial scale factor in an array format. Cutting a designated scaled location along the ceramic core to remove flash. Repeating process for additional scaled locations along the ceramic core.

Abstract: Systems and methods to determine a risk factor related to dehydration and thermal stress of a subject are disclosed. Exemplary implementations may: generate output signals, by one or more sensors worn on a body of a subject, conveying information related to one or more of location of the subject, motion of the subject, temperature of the subject, cardiovascular parameters of the subject; store information related to the subject; obtain the output signals; determine in an ongoing manner, from the output signals, values of a water loss metric that correlates with estimated percentage of bodyweight of the subject lost in water; obtain heat index information for a contextual environment surrounding the subject; determine in an ongoing manner, from the output signals, values of an exertion metric that correlates with exertion of the subject due to work; and determine in an ongoing manner values for an aggregated risk factor of the subject.

Abstract: A regenerator cell for regenerating metallic particles is provided. The regenerator cell includes: a housing for containing a quantity of electrolyte; an anode; a cathode; a cavity at least partially defined by the housing, the cathode and the anode; an inlet port for supplying electrolyte to the cell, the inlet port in fluid communication with the cavity; and an outlet port for expelling electrolyte, particles and/or gas from the cell, the outlet port in fluid communication with the cavity.

Abstract: A bone plate assembly includes a bone plate and a rotatable lock. The bone plate includes a superior surface, an inferior surface, and at least one screw through-hole that is configured to receive a bone screw. The bone plate includes a locking cavity that defined in the superior surface. The locking cavity includes a bottom surface that is recessed relative to the superior surface, and also includes a post that extends upwards from the bottom surface. The rotatable lock is supported on the post such that the rotatable lock is at least partially within the locking cavity.

Abstract: Fiber optic networks having cable assemblies with a predetermined cable-to-connector orientation that cooperate with a multiport so that the cables of the cable assemblies may be routed to the multiport and organized in an efficient and compact manner. In one embodiment, the cable assembly has a fiber optic connector terminated to a cable with a cross-section so that a major axis of the cable cross-section is aligned with a keying portion and locking feature of fiber optic connector. The cable-to-connector orientation allows cable assemblies to be optically connected to the multiport so that the cables may be routed away from the multiport along the connection plane of the multiport in the fiber optic network.

Abstract: A floating liquid intake for a liquid suction removal system, the liquid intake comprising housing defining an internal cavity. The housing has a hollow and buoyant annular body, an upper cover and a lower cover. The internal cavity is formed between the upper and lower covers. A substantially annular inlet is formed in the annular body for ingress of liquid into the cavity. The annular body has a buoyancy sufficient for the liquid intake to float in a liquid with the annular inlet submerged below the surface of the liquid in which the liquid intake is floating. A pipe extends into the cavity and the pipe includes an inlet that in use is open below the surface of the liquid within the cavity. The pipe extends outside of the cavity for connection to a liquid suction removal system.

Abstract: A drain line cleaning system including a housing, a pump carried by the housing, a line cleaning agent carrying tube in communication with the pump, a controller in communication with the pump, and a power supply carried by the housing and connected to the pump and the controller. The line cleaning agent carrying tube includes an intake that is connectable to a reservoir that carries line cleaning agent and an output that is connectable to a drain line. The controller controls the pump to function to withdraw the line cleaning agent from the reservoir and causes the line cleaning agent to be expelled through the output.