Abstract: A energy storage device for cycling between a charged state and a discharged state, the energy storage device including an enclosure, an electrode assembly and a non-aqueous liquid electrolyte within the enclosure, and a constraint that maintains a pressure on the electrode assembly as the energy storage device is cycled between the charged and the discharged states.

Abstract: Methods of manufacturing a light-activated powder are provided which provide solid-state generation and release of chlorine dioxide without detectable amounts of any toxic by-products such as chlorine gas, chlorites, or chlorates. The powder need not be exposed to moisture, relative humidity, or an acid before or during exposure of the powder to visible light to generate the gas. The powder can also be prepared under conditions that minimize or prevent decomposition or oxidation of sodium chlorite or premature light activation of the powder during the manufacturing process to maximize its activity.

Abstract: A secondary battery is provided for cycling between a charged and a discharged state, the secondary battery including a battery enclosure, an electrode assembly, carrier ions, a non-aqueous liquid electrolyte within the battery enclosure, and a set of electrode constraints. The set of electrode constraints includes a primary constraint system having first and second primary growth constraints and at least one primary connecting member, the first and second primary growth constraints separated from each other in the longitudinal direction, wherein the primary constraint array restrains growth of the electrode assembly in the longitudinal direction such that any increase in the Feret diameter of the electrode assembly in the longitudinal direction over 20 consecutive cycles of the secondary battery is less than 20%.

Abstract: Methods of manufacturing a moisture-activated powder are provided which provide generation and release of chlorine dioxide without detectable amounts of any toxic by-products such as chlorine gas, chlorites, or chlorates. The powder need not be exposed to light before or during exposure of the powder to moisture or relative humidity to generate the gas. The powder can also be prepared under conditions that minimize or prevent decomposition or oxidation of sodium chlorite or premature moisture activation of the powder during the manufacturing process to maximize its activity.

Abstract: According to the subject-matter of the present disclosure, there is provided an electrically powered fan engine. The fan engine includes: an energiser chamber between an inlet and an exhaust of the electrically powered fan engine; a first rotor within the energiser chamber, the first rotor including a plurality of blades and being configured to receive a fluid from the inlet and configured to rotate at a first velocity; and a second rotor within the energiser chamber, the second rotor including a plurality of blades and being configured to receive the fluid after passing through the first rotor and configured to rotate at a second velocity. The first velocity is different from the second velocity.

Abstract: Provided herein are methods for integrating a gene of interest into a chromosome of a host cell. In some embodiments, the methods include introducing into a host cell a first plasmid comprising a transposase coding sequence and a donor sequence, which includes a selectable marker coding sequence flanked by a first and a second lox site and is itself flanked by inverted repeats recognized by the transposase. Following transposase-mediated chromosomal integration of the donor sequence into the host cell, a second plasmid is introduced, which comprises the gene of interest and a second selectable marker coding sequence, both flanked by a first and a second lox site. The gene of interest is chromosomally integrated into the host cell by recombinase-mediated cassette exchange (RMCE) between the donor sequence and the second plasmid via Cre-lox recombination. Further provided herein are host cells, vectors, and methods of producing a product related thereto.

Abstract: Methods of manufacturing a light-activated powder are provided which provide solid-state generation and release of chlorine dioxide without detectable amounts of any toxic by-products such as chlorine gas, chlorites, or chlorates. The powder need not be exposed to moisture, relative humidity, or an acid before or during exposure of the powder to visible light to generate the gas. The powder can also be prepared under conditions that minimize or prevent decomposition or oxidation of sodium chlorite or premature light activation of the powder during the manufacturing process to maximize its activity.

Abstract: Provided herein are methods for integrating a gene of interest into a chromosome of a host cell. In some embodiments, the methods include introducing into a host cell a first plasmid comprising a transposase coding sequence and a donor sequence, which includes a selectable marker coding sequence flanked by a first and a second lox site and is itself flanked by inverted repeats recognized by the transposase. Following transposase-mediated chromosomal integration of the donor sequence into the host cell, a second plasmid is introduced, which comprises the gene of interest and a second selectable marker coding sequence, both flanked by a first and a second lox site. The gene of interest is chromosomally integrated into the host cell by recombinase-mediated cassette exchange (RMCE) between the donor sequence and the second plasmid via Cre-/cuc recombination. Further provided herein are host cells, vectors, and methods of producing a product related thereto.

Abstract: Systems and methods of epidemiological modeling using machine learning are provided, and can include receiving values for an occurrence of the infectious disease during a first time period, generating, from a model trained by a machine learning system, predictions for the occurrence of the infectious disease over a second time period, performing, by a simulator using the predictions, one or more simulations of the occurrence of the infectious disease in one or more geographic regions during one or more time periods subsequent to the second time period, and providing, to a user interface, a first simulation of the one or more simulations performed by the simulator for a first geographic region of the one or more geographic regions during a time period of the one or more time periods.

Abstract: An air leak detection system for chest tube collection systems includes a light emitting element, such as an LED, and a photodetector that can detect reflected light emission generated by the light emitting element. The air leak detection system can include a securement component, such as a transparent clip or adhesive, so that the air leak detection system is compatible with any conventional chest tube collection system. In certain embodiments, the light emitting element is positioned closer to the bottom portion of the water seal tube than the photodetector. In certain embodiments, the photodetector is positioned closer to a bottom of the water seal chamber than the light emitting element. In certain embodiments, the air leak detection system is part of a chest tube drainage system. A method of detecting an air leak in a chest tube collection system is also disclosed.

Abstract: Cancer is a complex group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Described herein are compositions and methods for the treatment of cancer.

Abstract: The present disclosure is drawn to wirebonding for optical engines having side-mounted optoelectronic components. An integrated circuit is mounted on a first surface of a substrate block, and an optoelectronic component is positioned on a second surface of the substrate block and is oriented to emit light in a direction parallel to a plane defined by the first surface. A wirebond is drawn between the integrated circuit and a base substrate on which the substrate block is mounted. A optoelectronic component is then contacted with the wirebond, and a portion of the wirebond between the optoelectronic component and the base substrate is removed.

Abstract: A chest tube placement apparatus is provided that has an elongate body with a rigid tip that is disposed within the interior of a flexible chest tube and an inflatable member mounted to the body is inflated and the apparatus is then inserted in a prepared location in the chest wall of a patient. The body of the apparatus has at least one axial material transfer channel with a tip port that permits the injection of anesthetic or the aspiration of gases or liquids at the tip. The body also has a light and video camera and display to allow the visualization of the internal structures of the patient during chest tube placement. Once placed and the fluids and gases aspirated, the inflatable member is deflated and the apparatus is removed from the interior of the placed chest tube.

Abstract: The present disclosure provides methods and systems for assigning a network topology to an interconnection network. Data is transmitted along at least one of a plurality of output ports based on a first port map, the first port map linking at least one of a plurality of input ports to at least one of the output ports. A request to apply a second port map, different from the first port map, is received. A circuit-switched element is activated to link at least one of the plurality of input ports to at least one of the plurality of the output ports based on the second port map. The data is transmitted along the at least one of the plurality of output ports based on the second port map.

Abstract: The present disclosure is drawn to wirebonding for optical engines having side-mounted optoelectronic components. An integrated circuit is mounted on a first surface of a substrate block, and an optoelectronic component is positioned on a second surface of the substrate block and is oriented to emit light in a direction parallel to a plane defined by the first surface. A wirebond is drawn between the integrated circuit and a base substrate on which the substrate block is mounted. A optoelectronic component is then contacted with the wirebond, and a portion of the wirebond between the optoelectronic component and the base substrate is removed.

Abstract: An air leak detection system for chest tube collection systems includes a light emitting element, such as an LED, and a photodetector that can detect reflected light emission generated by the light emitting element. The air leak detection system can include a securement component, such as a transparent clip or adhesive, so that the air leak detection system is compatible with any conventional chest tube collection system. In certain embodiments, the light emitting element is positioned closer to the bottom portion of the water seal tube than the photodetector. In certain embodiments, the photodetector is positioned closer to a bottom of the water seal chamber than the light emitting element. In certain embodiments, the air leak detection system is part of a chest tube drainage system. A method of detecting an air leak in a chest tube collection system is also disclosed.

Abstract: A photovoltaic device, particularly a solar cell, comprises an interface between a layer of Group III-V material and a layer of Group IV material with a thin silicon diffusion barrier provided at or near the interface. The silicon barrier controls the diffusion of Group V atoms into the Group IV material, which is doped n-type thereby. The n-type doped region can provide the p-n junction of a solar cell in the Group IV material with superior solar cell properties. It can also provide a tunnel diode in contact with a p-type region of the III-V material, which tunnel diode is also useful in solar cells.

Abstract: Cancer is a complex group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Described herein are compositions and methods for the treatment of cancer.

Abstract: Provided herein are methods for integrating a gene of interest into a chromosome of a host cell. In some embodiments, the methods include introducing into a host cell a first plasmid comprising a transposase coding sequence and a donor sequence, which includes a selectable marker coding sequence flanked by a first and a second lox site and is itself flanked by inverted repeats recognized by the transposase. Following transposase-mediated chromosomal integration of the donor sequence into the host cell, a second plasmid is introduced, which comprises the gene of interest and a second selectable marker coding sequence, both flanked by a first and a second lox site. The gene of interest is chromosomally integrated into the host cell by recombinase-mediated cassette exchange (RMCE) between the donor sequence and the second plasmid via Cre-/cuc recombination. Further provided herein are host cells, vectors, and methods of producing a product related thereto.

Abstract: Cancer is a complex group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Described herein are compositions and methods for the treatment of cancer.