Abstract: In one embodiment, a method includes accessing sensor data captured by sensors, wherein the sensor data is associated with a first pet, detecting activities of the first pet within a specified time period based on the sensor data, determining health indicators of the first pet based on one or more of the activities, wherein the health indicators are based on metrics associated with the one or more activities, generating a wellness assessment of the first pet based on the health indicators, wherein the wellness assessment comprises one or more of a wellness score or an alert of a possible medical condition, and sending instructions to a user device for presenting the wellness assessment of the first pet to a user.

Abstract: Disclosed herein are methods of administering relatively high doses of dexmedetomidine or a pharmaceutically acceptable salt thereof to a human subject, without also inducing significant sedation. The disclosed methods are particularly suitable for the treatment of agitation, especially when associated with neurodegenerative and/or neuropsychiatric diseases such as schizophrenia, bipolar illness such as bipolar disorder or mania, dementia, depression, or delirium.

Abstract: Disclosed herein are methods of administering relatively high doses of dexmedetomidine or a pharmaceutically acceptable salt thereof to a human subject, without also inducing significant sedation. The disclosed methods are particularly suitable for the treatment of agitation, especially when associated with neurodegenerative and/or neuropsychiatric diseases such as schizophrenia, bipolar illness such as bipolar disorder or mania, dementia, depression, or delirium.

Abstract: Disclosed herein are methods of administering relatively high doses of dexmedetomidine or a pharmaceutically acceptable salt thereof to a human subject, without also inducing significant sedation. The disclosed methods are particularly suitable for the treatment of agitation, especially when associated with neurodegenerative and/or neuropsychiatric diseases such as schizophrenia, bipolar illness such as bipolar disorder or mania, dementia, depression, or delirium.

Abstract: Embodiments of the disclosure are drawn to an enteral feeding device for hydrolyzing triglycerides in a nutritional formula. The device may include a body housing a chamber, an inlet configured to fluidly couple with a source of nutritional formula, and an outlet configured to fluidly couple with an enteral feeding tube. The device may include a headspace and a plurality of particles contained within the chamber, wherein the lipase is covalently bonded to the plurality of particles. The device may include an inlet filter located between the inlet and the chamber, wherein the inlet filter contains a first plurality of openings, and an outlet filter located between the chamber and the outlet, wherein the outlet filter has a second plurality of openings smaller than the plurality of particles.

Abstract: The embodiments disclose a method including capturing video footage of a youth sports event using at least one video camera with a mobile application installed, transmitting to at least one network server with internet and WI-FI connectivity mobile application multi-camera live-streaming video camera captured game footage, recording on at least one database coupled to the network server at least one video camera mobile application multi-camera live-streaming video camera captured game footage, using at least one network computer coupled to at least one network server configured for processing and displaying multi-camera live-streaming video camera captured game footage for live video streaming game broadcast on a plurality of subscribed viewer digital devices, and mixing advertising into the processed multi-camera live-streaming video camera captured game footage broadcast using the at least one network computer.

Abstract: An aerosol-generating system is provided, including: an aerosol-forming substrate; a first electrode and a second electrode spaced apart from the first electrode; an aerosol-generating device including a power supply, and a controller configured to connect to the first electrode and the second electrode; and a capacitor including the first electrode, the second electrode, and at least a portion of the aerosol-forming substrate, the controller being configured to supply an alternating voltage to the first electrode and the second electrode for dielectrically heating the aerosol-forming substrate, measure or determine an electrical property between the first electrode and the second electrode, and control heating of the aerosol-forming substrate based on the measured or determined electrical property.

Abstract: Aspects of the present disclosure provide a computer-implemented method that includes obtaining the medical condition of the individual based at least in part on a personal identifier associated with the individual, the medical condition being determined by performing natural language processing of medical information associated with the individual. The method further includes obtaining characteristics of the plurality of items. The method further includes comparing the characteristics of the plurality of items to a restriction associated with the medical condition of the individual. The method further includes, responsive to determining that at least one of the characteristics of the plurality of items violates the restriction associated with the medical condition of the individual, preventing the individual from obtaining the item of the plurality of items associated with the violation.

Abstract: Embodiments of the disclosure are drawn to an enteral feeding device for hydrolyzing triglycerides in a nutritional formula. The device may include a body housing a chamber, an inlet configured to fluidly couple with a source of nutritional formula, and an outlet configured to fluidly couple with an enteral feeding tube. The device may include a headspace and a plurality of particles contained within the chamber, wherein the lipase is covalently bonded to the plurality of particles. The device may include an inlet filter located between the inlet and the chamber, wherein the inlet filter contains a first plurality of openings, and an outlet filter located between the chamber and the outlet, wherein the outlet filter has a second plurality of openings smaller than the plurality of particles.

Abstract: Systems and methods for detecting low impact collisions for a vehicle (100). The system includes at least one sensor (99, 110, 111, 115, 120-123, 125-136, 140, 141) and an electronic controller (150). The electronic controller (150) is configured to receive sensor data from the sensor (99, 110, 111, 115, 120-123, 125-136, 140, 141) and determine one or more features of the sensor data received from the at least one sensor. The electronic controller (150) is further configured to determine if a collision has occurred based upon the one or more features of the sensor data, and take at least one action in response to determining that the collision has occurred.

Abstract: The present invention relates to processes for preparing linkers that are useful in the conjugation of therapeutic molecules (e.g., cytotoxic agents) with targeting moieties (e.g., proteins, peptides, antibodies, nanoparticles, nucleic acids). During said processes lipases like lipase B from Candida antarctica were used for enantioselective resolution of (S,S)-2-benzylthiocyclohexanol or (S,S)-2-benzylthiocycloheptanol in presence of acylating agent which are reduced for deprotection to yield (S,S)-2-mercaptocyclohexanol or (S,S)-2-mercaptocyclopentanol which can then be used for linking therapeutic with targeting moieties.

Abstract: A hand held electric pulse tool performs tightening operations in which torque is delivered in pulses to tighten a screw joint. The tool includes an output shaft and a sensor to determine a parameter value associated with tightening of the screw joint. The tool is operative to provide torque pulses on the output shaft in a tightening direction until a first parameter value associated with the tightening of the screw joint is reached, then pause the tightening during a first time interval, and then provide torque pulses on the output shaft in a loosening direction until a second parameter value is reached. Next the electrical pulse tool is operative to pause the tightening during a second time interval and provide torque pulses on the output shaft in the tightening direction until a third parameter value is reached.

Abstract: Embodiments of the disclosure are drawn to an enteral feeding device for hydrolyzing triglycerides in a nutritional formula. The device may include a body housing a chamber, an inlet configured to fluidly couple with a source of nutritional formula, and an outlet configured to fluidly couple with an enteral feeding tube. The device may include a headspace and a plurality of particles contained within the chamber, wherein the lipase is covalently bonded to the plurality of particles. The device may include an inlet filter located between the inlet and the chamber, wherein the inlet filter contains a first plurality of openings, and an outlet filter located between the chamber and the outlet, wherein the outlet filter has a second plurality of openings smaller than the plurality of particles.

Abstract: The present disclosure provides lyophilates comprising (S)-isopropyl 2-((S)-2-acetamido-3-(1H-indol-3-yl)propanamido)-6-diazo-5-oxohexanoate: for subcutaneous administration to a subject, and pharmaceutical compositions, pharmaceutical formulations, and uses thereof

Abstract: Various examples are provided related to optical ground wire (OPGW) designs and mitigation of impulse effects. In one example, an optical ground cable includes one or more inner optical fiber; and a shield surrounding the one or more inner optical fiber. The shield includes a shield material have a skin-depth less than a skin-depth of aluminum which can improve rejection of intrusive signals and communications capabilities. Conductivity of the shield material can be greater than the conductivity of aluminum and permeability of the shield material can be greater than the permeability of aluminum.

Abstract: The image processing circuit includes a gamma correction circuit configured to perform a gamma correction on input image data using a look-up table, and then output output image data, an output image histogram calculation circuit configured to calculate an output image histogram, an input image histogram calculation circuit configured to calculate an input image histogram, a reference histogram calculation circuit configured to calculate a reference histogram from the input image histogram based on the look-up table, and a histogram comparison circuit configured to perform a comparison between the output image histogram and the reference histogram.

Abstract: The present disclosure provides a method of preparing a compound of Formula I, wherein R1 is C1-C4 alkyl; R2 is C1-C4 alkyl; and R3 is selected from the group consisting of C1-C6 alkyl, (aryl)alkyl, and (heteroaryl)alkyl in >95% chemical purity and >95% enantiomeric excess.

Abstract: A method and a device for detecting the oil level in a hydraulic pulse unit at an impulse type power wrench, wherein the pulse unit comprises an oil filled pulse chamber, a motor driven inertia drive member, and a kinetic energy receiving member connected to an output shaft and intermittently coupled to the inertia drive member via an oil cushion to receive kinetic energy from the inertia drive member during repeated energy transfer phases. The rotation speed of the inertia drive member is measured both at the start of a pulse generating phase and at the end of that phase, wherein the two measured speeds are compared to each other, and when the speed at the end of the pulse generating phase exceeds the speed at the end of that phase by a certain percentage a faulty signal is emitted indicating a too low oil level in the pulse unit.

Abstract: An electric tool adapted to perform tightening operations where torque is delivered in pulses to tighten a screw joint. The electric tool including an electric motor drivingly connected to an output shaft. A processor and a memory storing software instructions that, when executed by the processor cause the electrical tool, retrieve a first power level parameter p1 indicating a first power level to be used for torque pulses up to a torque threshold. And retrieve a second power level parameter p2 indicating a second power level to be used for torque pulses above the torque threshold. Then control the speed of the electric motor, so that the electric tool provide torque pulses on the output shaft with the first power level p1 until the torque threshold is reached. And control the speed of the electric motor, so that the electric tool provide torque pulses on the output shaft with the second power level p2.

Abstract: System for generating syngas includes a primary reactor chamber operable to receive material, a plurality of first-stage gas pipes connected to the primary reactor chamber, and a secondary reactor chamber. The primary reactor chamber comprises a plurality of electrodes at least partially protruding into the primary reactor chamber, the electrodes operable to generate an arc capable to generate first-stage gas from breakdown of the material within the primary reactor chamber when electricity is applied to the electrodes. The secondary reactor chamber is operable to receive the first-stage gas via the first-stage gas pipes and to receive water vapor. The first-stage gas combines and interacts with the water vapor to form second-stage gas. Each of the first-stage gas pipes comprise a portion protruding into the secondary reactor chamber that together are adapted to direct the flow of first-stage gas to generate turbulence within the secondary reactor chamber.