Abstract: The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.

Abstract: In some embodiments a Stand Up Pouch (SUP) is prepared using a polyethylene structure having a first web and a second web. The webs are laminated together to form the polyethylene structure that is used to prepare the SUP. One web contains a layer of recycled polyethylene (r.PE). In some instances, the use of r.PE has been observed to reduce the effectiveness of the sealant layer of the overall structure. In some embodiments, the SUP disclosed herein has a two layer sealant system to mitigate this problem.

Abstract: Multilayer Films have a first skin layer that is prepared from a high density polyethylene and a second skin layer (also referred to as the sealant layer) that is prepared from a linear low density polyethylene (LLDPE) having a density of from 0.90 to 0.92 g/cc and a Dilution Index, Yd, of greater than 0°. Seals can be prepared by placing two pieces of this film against each other such that the sealant layers are in contact with each other, then applying heat to at least one high density skin layer such that heat is transmitted/conducted through the multilayer film in a sufficient amount to melt the sealant layer and form a seal. The use of LLDPE having a Dilution Index of greater than 0° has been found to improve the sealing performance of multilayer films in comparison to multilayer films where the sealant layer is a conventional LLDPE having a Dilution Index of less than 0°.

Abstract: Multilayer Films have a first skin layer that is prepared from a high density polyethylene and a second skin layer (also referred to as the sealant layer) that is prepared from a linear low density polyethylene (LLDPE) having a density of from 0.90 to 0.92 g/cc and a Dilution Index, Yd, of greater than 0°. Seals can be prepared by placing two pieces of this film against each other such that the sealant layers are in contact with each other, then applying heat to at least one high density skin layer such that heat is transmitted/conducted through the multilayer film in a sufficient amount to melt the sealant layer and form a seal. The use of LLDPE having a Dilution Index of greater than 0° has been found to improve the sealing performance of multilayer films in comparison to multilayer films where the sealant layer is a conventional LLDPE having a Dilution Index of less than 0°.

Abstract: Multilayer Films have a first skin layer that is prepared from a high density polyethylene and a second skin layer (also referred to as the sealant layer) that is prepared from a linear low density polyethylene (LLDPE) having a density of from 0.90 to 0.92 g/cc and a Dilution Index, Yd, of greater than 0°. Seals can be prepared by placing two pieces of this film against each other such that the sealant layers are in contact with each other, then applying heat to at least one high density skin layer such that heat is transmitted/conducted through the multilayer film in a sufficient amount to melt the sealant layer and form a seal. The use of LLDPE having a Dilution Index of greater than 0° has been found to improve the sealing performance of multilayer films in comparison to multilayer films where the sealant layer is a conventional LLDPE having a Dilution Index of less than 0°.

Abstract: Multilayer Films have a first skin layer that is prepared from a high density polyethylene and a second skin layer (also referred to as the sealant layer) that is prepared from a linear low density polyethylene (LLDPE) having a density of from 0.90 to 0.92 g/cc and a Dilution Index, Yd, of greater than 0°. Seals can be prepared by placing two pieces of this film against each other such that the sealant layers are in contact with each other, then applying heat to at least one high density skin layer such that heat is transmitted/conducted through the multilayer film in a sufficient amount to melt the sealant layer and form a seal. The use of LLDPE having a Dilution Index of greater than 0° has been found to improve the sealing performance of multilayer films in comparison to multilayer films where the sealant layer is a conventional LLDPE having a Dilution Index of less than 0°.

Abstract: The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.

Abstract: Multilayer Films have a first skin layer that is prepared from a high density polyethylene and a second skin layer (also referred to as the sealant layer) that is prepared from a linear low density polyethylene (LLDPE) having a density of from 0.90 to 0.92 g/cc and a Dilution Index, Yd, of greater than 0°. Seals can be prepared by placing two pieces of this film against each other such that the sealant layers are in contact with each other, then applying heat to at least one high density skin layer such that heat is transmitted/conducted through the multilayer film in a sufficient amount to melt the sealant layer and form a seal. The use of LLDPE having a Dilution Index of greater than 0° has been found to improve the sealing performance of multilayer films in comparison to multilayer films where the sealant layer is a conventional LLDPE having a Dilution Index of less than 0°.

Abstract: Multilayer Films have a first skin layer that is prepared from a high density polyethylene and a second skin layer (also referred to as the sealant layer) that is prepared from a linear low density polyethylene (LLDPE) having a density of from 0.90 to 0.92 g/cc and a Dilution Index, Yd, of greater than 0°. Seals can be prepared by placing two pieces of this film against each other such that the sealant layers are in contact with each other, then applying heat to at least one high density skin layer such that heat is transmitted/conducted through the multilayer film in a sufficient amount to melt the sealant layer and form a seal. The use of LLDPE having a Dilution Index of greater than 0° has been found to improve the sealing performance of multilayer films in comparison to multilayer films where the sealant layer is a conventional LLDPE having a Dilution Index of less than 0°.

Abstract: The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.

Abstract: A flexible package made with a multilayer polyethylene film and an integral fitment; and a process to prepare the flexible package are disclosed. The amount of polyethylene used to prepare the package is at least 90 weight % of the total weight of polymer used to prepare the package, which allows the package to be recycled. The fitment is made from a linear low density polyethylene which facilitates the manufacture of the package.

Abstract: A functional rail system is mounted to the top of a modular office panel and supports a worksurface on the rail with the worksurface locked in position along the rail. The rail includes a channel in the upper surface for receiving an accessory, and a side accessory slot for mounting the worksurface. The worksurface may be mounted via an upper bracket and a lower bracket interfitted with each other and the side accessory slot to frictionally lock the brackets in place along the longitudinal length of the slot.

Abstract: The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.

Abstract: A functional rail system is mounted to the top of a modular office panel and supports a worksurface on the rail with the worksurface locked in position along the rail. The rail includes a channel in the upper surface for receiving an accessory, and a side accessory slot for mounting the worksurface. The worksurface may be mounted via an upper bracket and a lower bracket interfitted with each other and the side accessory slot to frictionally lock the brackets in place along the longitudinal length of the slot.

Abstract: A connector arrangement for a wall panel system is provided which includes connector blocks that join serially-adjacent wall panel frames together in proper alignment with each other. These corner blocks also are matable with a system of spacer strips, light block strips, single-side trim covers and multi-side trim covers which enclose the connector blocks and connector structure. A corner spline arrangement is also provided between adjacent trim covers which spline extends vertically and defines a closed corner, right-angled corner between the interconnected trim covers.

Abstract: A connector arrangement for a wall panel system is provided which includes connector blocks that join serially-adjacent wall panel frames together in proper alignment with each other. These corner blocks also are matable with a system of spacer strips, light block strips, single-side trim covers and multi-side trim covers which enclose the connector blocks and connector structure. A corner spline arrangement is also provided between adjacent trim covers which spline extends vertically and defines a closed corner, right-angled corner between the interconnected trim covers.

Abstract: A connector arrangement for a wall panel system is provided which includes connector blocks that join serially-adjacent wall panel frames together in proper alignment with each other. These corner blocks also are matable with a system of spacer strips, light block strips, single-side trim covers and multi-side trim covers which enclose the connector blocks and connector structure. A corner spline arrangement is also provided between adjacent trim covers which spline extends vertically and defines a closed corner, right-angled corner between the interconnected trim covers.

Abstract: A connector arrangement for a wall panel system is provided which includes connector blocks that join serially-adjacent wall panel frames together in proper alignment with each other. These corner blocks also are matable with a system of spacer strips, light block strips, single-side trim covers and multi-side trim covers which enclose the connector blocks and connector structure. A corner spline arrangement is also provided between adjacent trim covers which spline extends vertically and defines a closed corner, right-angled corner between the interconnected trim covers.

Abstract: A connector arrangement for a wall panel system is provided which includes connector blocks that join serially-adjacent wall panel frames together in proper alignment with each other. These corner blocks also are matable with a system of spacer strips, light block strips, single-side trim covers and multi-side trim covers which enclose the connector blocks and connector structure. A corner spline arrangement is also provided between adjacent trim covers which spline extends vertically and defines a closed corner, right-angled corner between the interconnected trim covers.

Abstract: A photovoltaic assembly includes a flexible photovoltaic module, a flexible back barrier layer, and electrically conductive first and second flexible bus bars. The photovoltaic module includes opposing front and back outer surfaces and first and second electrical contacts on the front outer surface. The photovoltaic module is adapted to generate an electrical potential difference between the first and second electrical contacts in response to light incident on the front outer surface. The flexible back barrier layer is disposed on the back outer surface of the photovoltaic module. The electrically conductive first and second flexible bus bars are electrically coupled to the first and second electrical contacts, respectively, and the first and second flexible bus bars wrap around the flexible photovoltaic module and extend through the back barrier layer.