Abstract: An improved drink can is disclosed wherein the drink can has a drink opening and a vent opening which are positioned opposite from each other with respect to a central portion of a top end of a drink can. The tab is attached to the central portion and can be pulled upward to open the drink opening then pushed back downward to open the vent opening. To aid in opening the vent opening with the tab, the vent opening may have a ridge to provide additional leverage when the tab pushes downward on a score line that defines the vent opening. The tab may be enlarged so that upon breakage of the score line to the vent opening, the tab contacts the top end of the can and does not allow the user's finger to proceed into the vent opening and possibly cut the user's finger.

Abstract: A fluid flow indicator for observation of low flow rates in liquids includes a capillary tube (12) slidably mounted at each end in passageways (4) and (5) and biased into a no-flow indicating position by a castellated elastomeric membrane (14) providing a sealed barrier within a chamber (1) between a first zone (17) and a second zone (18). Fluid flow introduced through spigot (9) causes the capillary tube (12) to slide to the opposite end of the passageways (4) and (5) whereupon the deformed position of the elastomeric membrane (14) can readily be observed through transparent walls (3) in the chamber (1). Upon cessation of flow, the elastomeric membrane (14) causes the capillary tube (12) to revert to its original position.

Abstract: The present invention is based, in part, on the unexpected discovery that particles for pulmonary delivery of a therapeutic, prophylactic or diagnostic agent that comprise a phospholipid and a sufficient amount of leucine can produce sustained effect of the agent. Specifically, particles for pulmonary delivery of a therapeutic, prophylactic or diagnostic agent that contain a phospholipid or combination of phospholipids, wherein the phospholipid or combination of phospholipids is present in the particles in an amount of about 1 to 46 weight percent; and leucine, wherein leucine is present in the particles in an amount of at least 46 weight percent, can contribute to sustained effect of the agent. Particles that comprise at least 46 weight percent leucine but that do not contain phospholipids do not exhibit these same sustained effect properties.

Abstract: A method of forming an anti-tamper mesh on an electronic device. The method includes forming at least one terminal on the electronic device and forming a conductive mesh on at least one surface of the electronic device, wherein the conductive mesh is in electrical contact with the terminal, and wherein the terminal facilitates electrical conduction between the conductive mesh and an electrical detection circuit.

Abstract: Flow-through systems for processing biological fluid are disclosed. The flow-through systems include a removal device in the flow path for removing unwanted compounds and agents. The removal device includes a removal media contained within a housing made of two separate portions sealed together. The housing is maintained in a substantially vertical disposition, thereby ensuring substantially uniform and complete exposure of the fluid to the media.

Abstract: A seaming assembly for placing seams in a continuously moving web of material. The seaming assembly includes a first support that is movable in a machine direction and a second support which is secured to the first support. The second support is movable relative to the first support in a cross direction. A seaming mechanism is mounted on the second support to place seams in the web that are at least partially in the cross direction. The first support may be movable in the machine direction at a speed that is substantially the same as the web such that the seaming mechanism places seams in the web that are substantially in the cross direction.

Abstract: A fluid flow indicator for observation of low flow rates in liquids includes a capillary tube (12) slidably mounted at each end in passageways (4) and (5) and biased into a no-flow indicating position by a castellated elastomeric membrane (14) providing a sealed barrier within a chamber (1) between a first zone (17) and a second zone (18). Fluid flow introduced through spigot (9) causes the capillary tube (12) to slide to the opposite end of the passageways (4) and (5) whereupon the deformed position of the elastomeric membrane (14) can readily be observed through transparent walls (3) in the chamber (1). Upon cessation of flow, the elastomeric membrane (14) causes the capillary tube (12) to revert to its original position.

Abstract: A hub and belt assembly for driving a poultry de-feathering machine includes multiple bearing heat dissipating hub that includes bearing isolators or spacers associated with each of the drive shaft bearings. The bearing isolators trap vapors, including water and the like that may accumulate from operation of the hub and belt assembly, and prevent this vapor from contacting the bearings.

Abstract: Methods and devices to determine rate of particle production and the size range for the particles produced for an individual are described herein. The device (10) contains a mouthpiece (12), a filter (14), a low resistance one-way valve (16), a particle counter (20) and a computer (30). Optionally, the device also contains a gas flow meter (22). The data obtained using the device can be used to determine if a formulation for reducing particle exhalation should be administered to an individual. This device is particularly useful prior to and/or following entry in a cleanroom to ensure that the cleanroom standards are maintained. The device can also be used to identify animals and humans who have an enhanced propensity to exhale aerosols (referred to herein as “over producers”, “super-producers”, or “superspreaders”). Formulations to reduce particle production are also described herein. The formulation is administered in an amount sufficient to alter biophysical properties in the mucosal linings of the body.

Abstract: A medical device, such as a vascular access device, is disclosed for providing access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.

Abstract: The present invention provides an apparatus, method and system for delivery of commercial cargo containers shore side without container terminals. The present invention utilizes containers made autonomous by coupling a container with a detachable propulsion system, having a motor and navigation and steering controls, permitting the rapid, controlled, efficient and safe delivery of cargo containers individually by water. Ballast units, deployment systems and control via remote units are also disclosed. These improvements allow the containers, utilizing their inherent buoyancy, to approach a shore autonomously according to a preplanned or remote controlled route to a specific location and in a specific order of arrival, thereby reducing the number of cargo handlers required, speeding the delivery process to the shore, and eliminating the need for high-technology pier-side equipment.

Abstract: Formulations have been developed for pulmonary delivery to treat or reduce the infectivity of diseases such as viral infections, especially tuberculosis, SARS, influenza and respiratory synticial virus in humans and hoof and mouth disease in animals, or to reduce the symptoms of allergy or other pulmonary disease. Formulations for pulmonary administration include a material that significantly alters physical properties such as surface tension and surface elasticity of lung mucus lining fluid, which may be isotonic saline and, optionally, a carrier. The formulation may be administered as a liquid solution, suspension, aerosol, or powder where the particles consist basically of an osmotically active solute. Drugs, especially antivirals or antibiotics, may optionally be included with the formulation. These may be administered with or incorporated into the formulation.

Abstract: An electric device comprises a gelled acid electrolyte (142A) in complex with a lanthanide that forms a redox pair with a second element. Preferred electric devices include batteries and especially primary batteries, while preferred acid electrolytes (124A) have a sulfonic acid group. Contemplated lanthanides especially include cerium, and preferred second elements particularly include zinc. Alternatively, contemplated electric devices may comprise a gelled electrolyte (142A) in which with a lanthanide forms a redox pair with zinc.

Abstract: A battery (100) comprises an electrolyte in which a lanthanide and zinc form a redox pair. Preferred electrolytes are acid electrolytes, and most preferably comprise methane sulfonic acid, and it is further contemplated that suitable electrolytes may include at least two lanthanides. Contemplated lanthanides include cerium, praseodymium, neodymium, terbium, and dysprosium, and further contemplate lanthanides are samarium, europium, thulium and ytterbium.

Abstract: A hub and belt assembly for driving a poultry de-feathering machine includes multiple bearing heat dissipating hub driven by a serrated timing belt. The hub assembly incorporates seals along a drive shaft to reduce wear caused by dirt. The timing belt synchronizes multiple picking hubs and reduces the friction driving required. The combination of a heat dissipating hub and the placement of seals along the drive shaft within the hub minimize maintenance and replacement.

Abstract: Conductive formulations containing conductive agents, such as salts, ionic surfactants, or other substances that are in an ionized state or easily ionized in an aqueous or organic solvent environment, and methods of use, have been developed. One or more active agents, such as antivirals, antimicrobials, anti-inflammatories, proteins or peptides, may optionally be included with the formulation. The active agent may be administered with or incorporated into the formulation, or may be administered after the conductive formulation is administered. When applied to mucosal lining fluids, the formulation alters the physical properties such as the surface tension, surface elasticity, and bulk viscosity of the mucosal lining. The formulation is administered in an amount sufficient to alter biophysical properties in the mucosal linings of the body.

Abstract: The invention relates to a method for treating a disease characterized by a constrictive airway comprising administering to a patient in need thereof via inhalation a pharmaceutical composition comprising trospium, wherein said patient achieves an effective therapy for at least 10 hours. The trospium composition is preferably a particulate formulation useful for administration via a dry powder inhaler. In a preferred embodiment, the composition further comprises a second active agent, such as a beta-2 agonist. A particularly preferred second active agent is formoterol, wherein the trospium, formoterol composition is manufactured by spray drying a mixture comprising trospium and formoterol.

Abstract: This invention relates to a hub and belt assembly for driving a poultry de-feathering machine and more particularly to a multiple bearing heat dissipating hub driven by a serrated timing belt. The hub assembly incorporates seals along a drive shaft to reduce wear caused by dirt. The timing belt synchronizes multiple picking hubs and reduces the friction driving required. The combination of a heat dissipating hub and the placement of seals along the drive shaft within the hub minimize maintenance and replacement.

Abstract: A method for manufacturing a semiconductor package that includes forming a frame inside a conductive can, the frame being unwettable by liquid solder.

Abstract: A system and method for transferring a continuously advancing paper web from a dryer to a reel section is provided. The system includes a first fabric defining a first moving conveyor. The first fabric may be a permeable fabric, which is positioned downstream from the dryer. A second fabric, which may also be permeable and defines a second moving conveyor, is also included. The first moving conveyor overlaps the second moving conveyor for a predetermined distance, and the first and second moving conveyors are configured to receive the paper web between the conveyors. A vacuum device is rotatably disposed against the first moving conveyor, and the dryer and the vacuum device are disposed relative to each other to form an open draw. The vacuum device is configured to produce a vacuum to attract the web to the first fabric for transferring the advancing web into the predetermined distance where the first and second conveyors overlap.