Patents by Inventor Robert A. Conradi

Robert A. Conradi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxy containing ester prodrugs of corticosteroids
    Patent number: 4588718
    Abstract: A compound of the formula ##STR1## wherein St represents a corticosteroid moiety bonded to the carbonyl via the21-hydroxy group of said corticosteroid;whereinZ is a bond or --O--;whereinn is an integer from 4 to 9;whereinQ is(1) Y--CH.sub.2 COOH wherein Y is --S--, --S(0)--, --S(0.sub.2)--, --SO.sub.2 N(R)--, or --N(R)SO.sub.2 ; R is hydrogen or lower alkyl(C.sub.1 -C.sub.4) with the proviso that the total carbon atoms in R and (CH.sub.2).sub.n is not greater than 10;(2) ##STR2## or (3) ##STR3## wherein R.sub.1 is hydrogen and R.sub.2 is H, CH.sub.3,CH.sub.2 COOH, CH.sub.2 CH.sub.2 COOH, CH.sub.2 OH, CH.sub.2 SH, CH.sub.2 CH.sub.2 SCH.sub.3, or CH.sub.2 Ph--(OH) wherein Ph is phenyl and Ph--(OH) is p-hydroxyphenyl; or R.sub.1 is CH.sub.3 and R.sub.2 is H; or R.sub.1 and R.sub.2 taken together are --CH.sub.2 CH.sub.2 CH.sub.2 --; or N(R.sub.1)CH(R.sub.2) COOH taken together is NHCH.sub.2 CONHCH.sub.2 COOH; and pharmaceutically salts thereof.
    Type: Grant
    Filed: March 28, 1984
    Date of Patent: May 13, 1986
    Assignee: The Upjohn Company
    Inventors: Bradley D. Anderson, Robert A. Conradi
  • Sulfonate containing ester prodrugs of corticosteroids
    Patent number: 4472392
    Abstract: Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1## and their salts.
    Type: Grant
    Filed: January 21, 1983
    Date of Patent: September 18, 1984
    Assignee: The Upjohn Company
    Inventors: Bradley D. Anderson, Robert A. Conradi
  • Sulfonate containing ester prodrugs of corticosteroids
    Patent number: 4469689
    Abstract: Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1## and their salts.
    Type: Grant
    Filed: March 30, 1983
    Date of Patent: September 4, 1984
    Assignee: The Upjohn Company
    Inventors: Bradley D. Anderson, Robert A. Conradi
  • Amine containing ester prodrugs of corticosteroids
    Patent number: 4456602
    Abstract: Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1##
    Type: Grant
    Filed: August 23, 1982
    Date of Patent: June 26, 1984
    Assignee: The Upjohn Company
    Inventors: Bradley D. Anderson, Robert A. Conradi
  • Amine containing ester prodrugs of corticosteroids
    Patent number: 4443440
    Abstract: Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1##
    Type: Grant
    Filed: August 30, 1982
    Date of Patent: April 17, 1984
    Assignee: The Upjohn Company
    Inventors: Bradley D. Anderson, Robert A. Conradi