Patents by Inventor Robert A. de Man

Robert A. de Man has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VIRAL VARIANTS AND METHODS FOR DETECTING SAME
    Publication number: 20130171620
    Abstract: The present invention relates generally to viral variants exhibiting reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogs and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic agents.
    Type: Application
    Filed: July 12, 2012
    Publication date: July 4, 2013
    Applicant: MELBOURNE HEALTH
    Inventors: Stephen A. LOCARNINI, Angeline I. Bartholomguez, Thein T. Aye, Robert A. de Man
  • VIRAL VARIANTS AND METHODS FOR DETECTING SAME
    Publication number: 20100203506
    Abstract: The present invention relates generally to viral variants exhibiting reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogs and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic agents.
    Type: Application
    Filed: May 9, 2008
    Publication date: August 12, 2010
    Applicant: MELBOURNE HEALTH
    Inventors: Stephen A. Locarnini, Angeline I. Bartholomeusz, Thein T. Aye, Robert A. de Man
  • Viral variants and methods for detecting same
    Publication number: 20030124096
    Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogues and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic regimes.
    Type: Application
    Filed: October 1, 2002
    Publication date: July 3, 2003
    Applicant: Western Health Care Network
    Inventors: Stephen A. Locarnini, Angeline I. Bartholomeusz, Thein T. Aye, Robert A. de Man
  • Viral variants and methods for detecting same
    Patent number: 6555311
    Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogues and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic regimes.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: April 29, 2003
    Assignee: Western Health Care Network
    Inventors: Stephen A Locarnini, Angeline I. Bartholomeusz, Thein T. Aye, Robert A. de Man
  • Viral variants and methods for detecting same
    Patent number: RE40233
    Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogues and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic regimes.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: April 8, 2008
    Assignee: Melbourne Health
    Inventors: Stephen A Locarnini, Angeline I Bartholomeusz, Thein T. Aye, Robert A. de Man