Patents by Inventor Robert A. Field

Robert A. Field has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccines based on hepatitis B core antigens
    Patent number: 9950050
    Abstract: The invention provides a protein comprising hepatitis B core antigen (HBcAg) with a sugar attached to an e1 loop. The protein may comprise a first and a second copy of HBcAg in tandem, wherein one or both copies of HBcAg has a sugar attached to the e1 loop. The first copy may have a sugar attached to the e1 loop and the second copy may comprise a peptide epitope in the e1 loop. The protein may be used to induce an immune response against the sugar and hence act as a vaccine.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: April 24, 2018
    Assignee: IQUR LIMITED
    Inventors: Michael Anthony Whelan, Robert A. Field, David J. Rowlands
  • VACCINES BASED ON HEPATITIS B CORE ANTIGENS
    Publication number: 20180071384
    Abstract: The invention provides a protein comprising hepatitis B core antigen (HBcAg) with a sequence of the formula XpZqXr in an e1 loop, wherein X is a negatively charged amino acid residue, Z is a positively charged amino acid residue, and p, q N and r are each independently an integer from 1 to 12, and wherein a sugar is attached to a Z residue. The protein may comprise a first and a second copy of HBcAg in tandem, wherein one or both copies of HBcAg has a sugar attached to the e1 loop. The first copy may have a sugar attached to the e1 loop and the second copy may comprise a peptide epitope in the e1 loop. The protein may be used to induce an immune response against the sugar and hence act as a vaccine.
    Type: Application
    Filed: March 24, 2016
    Publication date: March 15, 2018
    Inventors: Michael Anthony Whelan, Robert A. Field, David J. Rowlands
  • VACCINES BASED ON HEPATITIS B CORE ANTIGENS
    Publication number: 20170049871
    Abstract: The invention provides a protein comprising hepatitis B core antigen (HBcAg) with a sugar attached to an e1 loop. The protein may comprise a first and a second copy of HBcAg in tandem, wherein one or both copies of HBcAg has a sugar attached to the e1 loop. The first copy may have a sugar attached to the e1 loop and the second copy may comprise a peptide epitope in the e1 loop. The protein may be used to induce an immune response against the sugar and hence act as a vaccine.
    Type: Application
    Filed: February 18, 2015
    Publication date: February 23, 2017
    Inventors: Michael Anthony Whelan, Robert A. Field, David J. Rowlands