Patents by Inventor Robert A. Ganz

Robert A. Ganz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060224220
    Abstract: A lower esophageal sphincter tightening device for treating gastroesophageal reflux disease which includes an insertion device, an energy source, and an energy transmitting device. The insertion device, by insertion through a body opening, positions the energy transmitting device in the proximity of the lower esophageal sphincter. The energy source generates and transmits energy via the insertion device to the energy transmitting device which directs the transmitted energy onto the lower esophageal sphincter which is comprised largely of collagen. The energy source transmits energy at a level sufficient to cause heating of the sphincter's collagen resulting in a shrinkage of the collagen and a tightening of the sphincter.
    Type: Application
    Filed: April 7, 2006
    Publication date: October 5, 2006
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Brian Zelickson, Robert Ganz
  • Patent number: 7107996
    Abstract: A method and apparatus for treating gum disease includes a light producing dental appliance that is accessible exteriorly of the body for placement within the mouth of the patient to expose the mouth to light radiation of a selected wavelength and in an amount that is effective for killing or debilitating pathogenic microorganisms and especially Porphyromona gingivalis within the mouth of the patient such that the bacterial load carried to the heart is diminished thereby reducing or eliminating the symptoms of coronary artery disease, atherosclerosis vascular inflammation and plaque formation.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: September 19, 2006
    Inventors: Robert A. Ganz, Brian D. Zelickson
  • Patent number: 7043307
    Abstract: A lower esophageal sphincter tightening device for treating gastroesophageal reflux disease which includes an insertion device, an energy source, and an energy transmitting device. The insertion device, by insertion through a body opening, positions the energy transmitting device in the proximity of the lower esophageal sphincter. The energy source generates and transmits energy via the insertion device to the energy transmitting device which directs the transmitted energy onto the lower esophageal sphincter which is comprised largely of collagen. The energy source transmits energy at a level sufficient to cause heating of the sphincter's collagen resulting in a shrinkage of the collagen and a tightening of the sphincter.
    Type: Grant
    Filed: August 4, 2003
    Date of Patent: May 9, 2006
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Brian D. Zelickson, Robert A. Ganz
  • Publication number: 20060069349
    Abstract: A method and apparatus is described that includes a catheter and a penetrating member at a distal end of the catheter for penetrating a tissue. The penetrating member can have a lumen in communication with the catheter, the lumen having an opening at a surface of the penetrating member to deliver a substance through the lumen. The device includes means for determining a location of the opening relative to the tissue.
    Type: Application
    Filed: September 19, 2005
    Publication date: March 30, 2006
    Inventors: Robert Ganz, Brian Zelickson, Mark Rydell
  • Publication number: 20050113908
    Abstract: To prevent intimal hyperplasia within a dialysis graft, a flexible tube comprising the dialysis graft is coated interiorly before placement with an anticarcinogen or mitosis-inhibiting agent for preventing cell division. The graft can also be irradiated with light energy by directing light into the lumen of the tube that has been grafted in place, thereby preventing or reducing dialysis graft intimal hyperplasia and reducing inflammation. The light source can be a light emitting diode (LED) or a chemical light source, i.e., a chemiluminescent substance for producing cool light energy within the graft to prevent or reduce the symptoms of GIH. When phototherapy is used, the body is exposed to light radiation at the site of the graft in sufficient amount to prevent undesired cell proliferation within the vessels, the graft, or surrounding tissue where the invention is used without detectable damage to body tissue. For various applications, visible light can be used, e.g.
    Type: Application
    Filed: November 22, 2004
    Publication date: May 26, 2005
    Inventors: Richard Sweet, Robert Ganz
  • Patent number: 6890346
    Abstract: A surgical apparatus has a body portion that includes a shaft terminating in a distal head or tip for directing light radiation from the apparatus onto the lining of a body cavity for treating an ailment in a body cavity of a patient as for example a gastrointestinal ailment of a patient such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, gastric lymphoma, ulcerative colitis, or Crohn's disease as well as for treating diseases of the circulatory system, urogenital systems and other body cavities. During use, the shaft of the apparatus is inserted into a body cavity, e.g., stomach or colon, of the patient to place the distal tip of the shaft in the desired position. The body cavity of the patient is then irradiated with light radiation so as to kill or debilitate microorganisms lining the body cavity without serious destruction of the body tissue of the patient to thereby improve or alleviate one or more of the symptoms of the ailment.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: May 10, 2005
    Assignee: LumeRx Inc.
    Inventors: Robert A. Ganz, Hans L. Melgaard
  • Publication number: 20050080465
    Abstract: A device includes a patch or bandage, applied on or adjacent to a specific external surface of a human or animal body part, which delivers light of varying wavelengths, intensity and duration for treatment of various diseases or abnormalities.
    Type: Application
    Filed: September 14, 2004
    Publication date: April 14, 2005
    Inventors: Brian Zelickson, Robert Ganz
  • Publication number: 20040215296
    Abstract: A system for treating abnormal mucosa in an esophagus comprises an access catheter, an energy delivery structure near a distal end of the access catheter, and a power supply for delivering energy through the energy delivery structure under conditions which injure or ablate the mucosal layer of the esophageal wall without causing substantial injury or heating of the submucosal layer. By injuring or necrosing metaplastic or other abnormal mucosal cells, regrowth of the mucosa substantially free from abnormal cells can be initiated.
    Type: Application
    Filed: January 9, 2004
    Publication date: October 28, 2004
    Applicant: BARRx, Inc.
    Inventors: Robert A. Ganz, Brian D. Zelickson, Roger A. Stern, Jerome Jackson, George H. Smith
  • Patent number: 6764501
    Abstract: Atherosclerotic vascular disease is treated by exposing the interior of an artery or vein to visible or ultraviolet light of a selected spectrum to thereby sterilize the artery, eradicating infectious pathogens and reverse the pathogenesis of atherosclerotic artery disease. A fiber optic bundle positioned via an intra-arterial catheter is connected to an appropriate light radiation source located outside of the body during treatment. In another form, the light energy is produced by means of a light energy source located at the distal tip of the instrument shaft positioned centrally within the atherosclerotic plaque formation. In this case, the power source at the distal tip of the instrument can be a light emitting diode (LED) or a transparent tube containing a chemilumlumenescent substance for producing cool light energy within the vessel to destroy the pathogenic microorganisms in the surrounding plaque or vessel without damage to the body tissue of the patient.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: July 20, 2004
    Inventor: Robert A. Ganz
  • Publication number: 20040138586
    Abstract: An apparatus includes a catheter for insertion into a stomach to introduce air into the stomach through the catheter and a pressure measurement device associated with the catheter to sense a pressure in the stomach. The pressure measurement device is used to determine a gastric yield pressure of the stomach when enough air has been introduced to the stomach to overcome the esophageal-gastric junction.
    Type: Application
    Filed: November 20, 2003
    Publication date: July 15, 2004
    Inventors: Robert A. Ganz, Mark Rydell
  • Publication number: 20040087936
    Abstract: A method, and system, are provided treating a tissue site of a tissue structure that has at least a first and a second tissue plane. An energy delivery device is provided. A barrier is created between the first and second tissue planes. At least a portion of an energy delivery device is positioned at the tissue site. Sufficient energy is delivered from the energy delivery device to create cell necrosis of at least a portion of the first tissue plane.
    Type: Application
    Filed: April 29, 2003
    Publication date: May 6, 2004
    Applicant: BARRx, Inc.
    Inventors: Roger A. Stern, Robert A. Ganz, Brian D. Zelickson
  • Publication number: 20030191459
    Abstract: A surgical apparatus has a body portion that includes a shaft terminating in a distal head or tip and a means for directing light radiation from the apparatus onto the lining of a body cavity for treating an ailment in a body cavity of a patient as for example a gastrointestinal ailment of a patient such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, gastric lymphoma, ulcerative colitis, or Crohn's disease as well as for treating diseases of the circulatory system, urogenital systems and other body cavities. The method of use of the apparatus comprises inserting the shaft of the apparatus into a body cavity, e.g., stomach or colon, of the patient to place the distal tip of the shaft in the desired position. The body cavity of the patient is then irradiated with light radiation so as to kill or debilitate microorganisms lining the body cavity without serious destruction of the body tissue of the patient to thereby improve or alleviate one or more of the symptoms of the ailment.
    Type: Application
    Filed: April 9, 2002
    Publication date: October 9, 2003
    Inventors: Robert A. Ganz, Hans L. Melgaard
  • Publication number: 20030158550
    Abstract: An ablation catheter system and method of use is provided to endoscopically access portions of the human esophagus experiencing undesired growth of columnar epithelium. The ablation catheter system and method includes controlled depth of ablation features and use of either radio frequency spectrum, non-ionizing ultraviolet radiation, warm fluid or microwave radiation, which may also be accompanied by improved sensitizer agents.
    Type: Application
    Filed: February 19, 2003
    Publication date: August 21, 2003
    Inventors: Robert A. Ganz, Brian D. Zelickson, Roger A. Stern
  • Patent number: 6604004
    Abstract: A lower esophageal sphincter tightening device for treating gastroesophageal reflux disease which includes an insertion device, an energy source, and an energy transmitting device. The insertion device, by insertion through a body opening, positions the energy transmitting device in the proximity of the lower esophageal sphincter. The energy source generates and transmits energy via the insertion device to the energy transmitting device which directs the transmitted energy onto the lower esophageal sphincter which is comprised largely of collagen. The energy sources transmits energy at a level sufficient to cause heating of the sphincter's collagen resulting in a shrinkage of the collagen and a tightening of the sphincter.
    Type: Grant
    Filed: October 4, 2001
    Date of Patent: August 5, 2003
    Inventors: Brian D. Zelickson, Robert A. Ganz
  • Publication number: 20030097122
    Abstract: A method and apparatus for treating gum disease includes a light producing dental appliance that is accessible exteriorly of the body for placement within the mouth of the patient to expose the mouth to light radiation of a selected wavelength and in an amount that is effective for killing or debilitating pathogenic microorganisms and especially Porphyromona gingivalis within the mouth of the patient such that the bacterial load carried to the heart is diminished thereby reducing or eliminating the symptoms of coronary artery disease, atherosclerosis vascular inflammation and plaque formation.
    Type: Application
    Filed: November 18, 2002
    Publication date: May 22, 2003
    Inventors: Robert A. Ganz, Brian D. Zelickson
  • Patent number: 6551310
    Abstract: An ablation catheter system and method of use is provided to endoscopically access portions of the human esophagus experiencing undesired growth of columnar epithelium. The ablation catheter system and method includes controlled depth of ablation features and use of either radio frequency spectrum, non-ionizing ultraviolet radiation, warm fluid or microwave radiation, which may also be accompanied by improved sensitizer agents.
    Type: Grant
    Filed: November 16, 2000
    Date of Patent: April 22, 2003
    Inventors: Robert A. Ganz, Brian D. Zelickson, Roger A. Stern
  • Patent number: 6491618
    Abstract: A surgical apparatus has a body portion that includes a shaft terminating in a distal head or tip and a means for directing light radiation from the apparatus onto the lining of a body cavity for treating a gastrointestinal ailment of a patient including gastritis, gastric ulcer, duodenal ulcer, gastric cancer, gastric lymphoma, ulcerative colitis, or Crohn's disease. The method of use of the apparatus comprises inserting the shaft of the apparatus into a body cavity, e.g., stomach or colon, of the patient to place the distal tip of the shaft in the desired position. The body cavity of the patient is then irradiated with ultraviolet light radiation in a preferred range of about 250 nm to 270 nm so as to kill or debilitate microorganisms lining the body cavity without serious destruction of the body tissue of the patient to thereby improve or alleviate one or more of the symptoms of the gastrointestinal ailment.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: December 10, 2002
    Inventor: Robert A. Ganz
  • Patent number: 6464625
    Abstract: A treatment method and apparatus for debilitating or killing Helicobacter pylori or other microorganisms within the body of a patient is especially suited for treating stomach or duodenal ulcers. The present therapeutic method involves the use of ionizing radiation for eliminating pathogenic microorganisms within or supported upon the lining of a body cavity of a patient, e.g., the stomach. An elongated flexible shaft is provided for insertion into the body in any of various ways selected by the surgeon. It can be placed endoscopically, e.g., through the esophagus, placed surgically, placed laparoscopically or by CAT scan-guided percutaneous insertion. A radiant energy distribution head is provided at the end of the flexible shaft to transmit ionizing radiation for destroying microorganisms within the body. Radiant energy, e.g.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: October 15, 2002
    Inventor: Robert A. Ganz
  • Publication number: 20020147443
    Abstract: A method and apparatus is described for eliminating atherosclerotic vascular disease by exposing the interior of an artery or vein to visible or ultraviolet light of a selected spectrum to thereby sterilize the artery, eradicating infectious pathogens and reverse the pathogenesis of atherosclerotic artery disease. The light energy can be supplied through a fiber optic bundle positioned via an intra-arterial catheter that is connected to an appropriate light radiation source located outside of the body during treatment. In another form of the invention, the light energy is produced by means of a light energy source located at the distal tip of the instrument shaft positioned centrally within the atherosclerotic plaque formation during treatment.
    Type: Application
    Filed: April 9, 2002
    Publication date: October 10, 2002
    Inventor: Robert A. Ganz
  • Publication number: 20010049464
    Abstract: A treatment method and apparatus for debilitating or killing Helicobacter pylori or other microorganisms within the body of a patient is especially suited for treating stomach or duodenal ulcers. The present therapeutic method involves the use of ionizing radiation for eliminating pathogenic microorganisms within or supported upon the lining of a body cavity of a patient, e.g., the stomach. An elongated flexible shaft is provided for insertion into the body in any of various ways selected by the surgeon. It can be placed endoscopically, e.g., through the esophagus, placed surgically, placed laparoscopically or by CAT scan-guided percutaneous insertion. A radiant energy distribution head is provided at the end of the flexible shaft to transmit ionizing radiation for destroying microorganisms within the body. Radiant energy, e.g.
    Type: Application
    Filed: June 23, 1999
    Publication date: December 6, 2001
    Inventor: ROBERT A. GANZ