Patents by Inventor Robert A. Graham

Robert A. Graham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150328364
    Abstract: A composition for making a cement or an implant, the composition comprising a silicate glass and at least one compound selected from the group consisting of a calcium phosphate salt, a strontium phosphate salt and a phosphate glass.
    Type: Application
    Filed: December 21, 2012
    Publication date: November 19, 2015
    Applicant: QUEEN MARY AND WESTFIELD COLLEGE
    Inventors: Robert Graham Hill, Natalia Karpukhina, Niall Kent
  • Patent number: 9184036
    Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: November 10, 2015
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Robert Graham Cooks, Jason Duncan, Guangming Huang, Guangtao Li, Xin Yan, Ewa Sokol, Xin Li
  • Patent number: 9184038
    Abstract: The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: November 10, 2015
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Robert Graham Cooks, Zane Baird, Wen-Ping Peng
  • Publication number: 20150306399
    Abstract: A neurostimulation device and system are provided. At least one neurostimulation lead having a plurality of electrodes is configured for being implanted within tissue of a patient. A shunt capacitance is coupled to one of the electrodes. Time-varying electrical current is delivered to at least one of the electrodes, wherein the shunt capacitance would, without compensation, absorb charge from or inject charge into the tissue in response to time-varying changes in the delivered electrical current, thereby causing an uncompensated electrical waveform to be delivered to the tissue adjacent the one electrode, The absorbed or injected charge is at least partially compensated for, thereby causing a compensated electrical waveform to be delivered to the tissue adjacent the one electrode.
    Type: Application
    Filed: April 21, 2015
    Publication date: October 29, 2015
    Inventors: Matthew Lee McDonald, Joseph M. Bocek, Thomas W. Stouffer, Robert Graham Lamont
  • Publication number: 20150309001
    Abstract: The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps.
    Type: Application
    Filed: January 23, 2014
    Publication date: October 29, 2015
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Robert Graham Cooks, Fred Paul Mark Jjunju, Anyin Li, Iman S. Roqan
  • Patent number: 9165752
    Abstract: The invention generally relates to systems and methods for sample analysis. In certain embodiments, the invention provides a system for analyzing a sample that includes a probe including a material connected to a high voltage source, a device for generating a heated gas, and a mass analyzer.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: October 20, 2015
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Guangtao Li, Xin Li, Zheng Ouyang
  • Patent number: 9159540
    Abstract: The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: October 13, 2015
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, Robert Graham Cooks, Sandilya Venkata Garimella, Jason David Harper, Nicholas Alan Charipar
  • Patent number: 9157921
    Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: October 13, 2015
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Livia Schiavinato Eberlin, Christina Ramires Ferreira, Allison Lisa Dill, Demian R. Ifa
  • Patent number: 9138268
    Abstract: A system, devices and methods are provided for facilitating stabilization of periarticular fractures. The system includes a compression plate and one or more of a cerclage cable for encircling the bone and securing the compression plate to the bone, a crimp lug for securing the cable in tension relative to the bone and/or a plate, and a supplemental plate coupled to the compression plate and adapted to receive bicortical or unicortical bone screws to further secure the compression plate relative to the bone. In addition, the system includes a cable tensioner for temporarily retaining the cable in tension and then applying a tension to the cable until a desired compression is effected between a plate and bone and while a cable retaining structure is secured to the cable to retain the applied tension on the cable. Also provided is a jig for use with plates for minimally invasive fracture stabilization.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: September 22, 2015
    Assignee: BIOMET C.V.
    Inventors: Cesare Cavallazzi, Robert Graham, Edward Mebarak, Javier E. Castaneda, Marcus Bourda, Joel G. Marquart, Victor Jose Alvarez
  • Patent number: 9138269
    Abstract: A system, devices and methods are provided for facilitating stabilization of periarticular fractures. The system includes a compression plate and one or more of a cerclage cable for encircling the bone and securing the compression plate to the bone, a crimp lug for securing the cable in tension relative to the bone and/or a plate, and a supplemental plate coupled to the compression plate and adapted to receive bicortical or unicortical bone screws to further secure the compression plate relative to the bone. In addition, the system includes a cable tensioner for temporarily retaining the cable in tension and then applying a tension to the cable until a desired compression is effected between a plate and bone and while a cable retaining structure is secured to the cable to retain the applied tension on the cable. Also provided is a jig for use with plates for minimally invasive fracture stabilization.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: September 22, 2015
    Assignee: BIOMET C.V.
    Inventors: Cesare Cavallazzi, Robert Graham
  • Publication number: 20150264391
    Abstract: Methods and encoders for tracing an error in a frame of a video to a subsequent frame of the video. In response to receiving an error notification message indicating an error has occurred in an encoded frame during decode, an encoder obtains: (a) the minimum and maximum horizontal motion vector components for each column of blocks of the frame immediately following the error frame; and (b) the minimum and maximum vertical motion vector components for each row of blocks of the frame immediately following the error frame. A rectangular region of blocks of the frame immediately following the error frame that the error is likely to have propagated to is identified using the minimum and maximum horizontal and vertical motion vector components.
    Type: Application
    Filed: March 12, 2015
    Publication date: September 17, 2015
    Inventors: Sudhanshu Sohoni, Parag Salasakar, Robert Graham Isherwood
  • Publication number: 20150262803
    Abstract: The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
    Type: Application
    Filed: January 12, 2015
    Publication date: September 17, 2015
    Inventors: Zheng Ouyang, Robert Graham Cooks, Sandilya Venkata Garimella, Jason David Harper, Nicholas Alan Charipar
  • Patent number: 9131968
    Abstract: A system, devices and methods are provided for facilitating stabilization of periarticular fractures. The system includes a compression plate and one or more of a cerclage cable for encircling the bone and securing the compression plate to the bone, a crimp lug for securing the cable in tension relative to the bone and/or a plate, and a supplemental plate coupled to the compression plate and adapted to receive bicortical or unicortical bone screws to further secure the compression plate relative to the bone. In addition, the system includes a cable tensioner for temporarily retaining the cable in tension and then applying a tension to the cable until a desired compression is effected between a plate and bone and while a cable retaining structure is secured to the cable to retain the applied tension on the cable. Also provided is a jig for use with plates for minimally invasive fracture stabilization.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: September 15, 2015
    Assignee: BIOMET C.V.
    Inventors: Cesare Cavallazzi, Javier E. Castaneda, Robert Graham
  • Patent number: 9116154
    Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of samples. In certain embodiments, the invention provides a mass spectrometry probe including at least one porous material connected to a high voltage source, in which the porous material is discrete from a flow of solvent.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: August 25, 2015
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, He Wang, Nicholas E. Manicke, Robert Graham Cooks, Qian Yang, Jiangjiang Liu
  • Publication number: 20150230738
    Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
    Type: Application
    Filed: April 16, 2015
    Publication date: August 20, 2015
    Inventors: Robert Graham Cooks, Zheng Ouyang, Chien-Hsun Chen, Ziqing Lin, Livia Schiavinato Eberlin
  • Patent number: 9075724
    Abstract: A multithreaded processor can concurrently execute a plurality of threads in a processor core. The threads can access a shared main memory through a memory interface; the threads can generate read and write transactions that cause shared main memory access. An incoherency detection module prevents incoherency by maintaining a record of outstanding global writes, and detecting a conflicting global read. A barrier is sequenced with the conflicting global write. The conflicting global read is allowed to proceed after the sequence of the conflicting global write and the barrier are cleared. The sequence can be maintained by a separate queue for each thread of the plurality.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: July 7, 2015
    Assignee: Imagination Technologies Limited
    Inventors: Robert Graham Isherwood, Yin Nam Ko
  • Patent number: 9061870
    Abstract: A winch for a sailboat comprises a support for mounting the winch with respect to a sailboat, a winch drum rotatable with respect to the support, a ring gear fixed with respect to the winch drum, a main drive gear meshing with the ring gear for driving rotation of the winch drum, a manual drive spindle 300 and a motor gear shaft 114. Forward winding of the winch drum in a first gearing ratio and in a second gearing ratio which are selected depending on the direction of rotation of the manual drive spindle. Gear trains provide the first and second gearing ratios. Manual and motorized operational arrangements are possible.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: June 23, 2015
    Assignee: LEWMAR LIMITED
    Inventors: Robert Graham Fields, Oliver Peter Gregory Falconer
  • Patent number: 9064674
    Abstract: The present invention generally relates to a low temperature plasma probe for desorbing and ionizing at least one analyte in a sample material and methods of use thereof. In one embodiment, the invention generally relates to a low temperature plasma probe including: a housing having a discharge gas inlet port, a probe tip, two electrodes, and a dielectric barrier, in which the two electrodes are separated by the dielectric barrier, in which application of voltage from a power supply generates a low temperature plasma, and in which the low temperature plasma is propelled out of the discharge region by the electric field and/or the discharge gas flow.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: June 23, 2015
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, Jason David Harper, Nicholas Alan Charipar, Robert Graham Cooks
  • Patent number: 9058967
    Abstract: A method of interfacing atmospheric pressure ion sources, including electrospray and desorption electrospray ionization sources, to mass spectrometers, for example miniature mass spectrometers, in which the ionized sample is discontinuously introduced into the mass spectrometer. Discontinuous introduction improves the match between the pumping capacity of the instrument and the volume of atmospheric pressure gas that contains the ionized sample. The reduced duty cycle of sample introduction is offset by operation of the mass spectrometer under higher performance conditions and by ion accumulation at atmospheric pressure.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: June 16, 2015
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, Liang Gao, Robert Graham Cooks
  • Publication number: 20150160981
    Abstract: Global register protection in a multi-threaded processor is described. In an embodiment, global resources within a multi-threaded processor are protected by performing checks, before allowing a thread to write to a global resource, to determine whether the thread has write access to the particular global resource. The check involves accessing one or more local control registers or a global control field within the multi-threaded processor and in an example, a local register associated with each other thread in the multi-threaded processor is accessed and checked to see whether it contains an identifier for the particular global resource. Only if none of the accessed local resources contain such an identifier, is the instruction issued and the thread allowed to write to the global resource. Otherwise, the instruction is blocked and an exception may be raised to alert the program that issued the instruction that the write failed.
    Type: Application
    Filed: February 19, 2015
    Publication date: June 11, 2015
    Inventors: Guixin Wang, Hugh Jackson, Robert Graham Isherwood