Patents by Inventor Robert A. Grothe

Robert A. Grothe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quadrupole mass spectrometer with enhanced sensitivity and mass resolving power
    Patent number: 8841610
    Abstract: A novel method and mass spectrometer apparatus is introduced to spatially and temporally resolve images of one or more ion exit patterns of a multipole instrument. In particular, the methods and structures of the present invention measures the ion current as a function of time and spatial displacement in the beam cross-section of a quadrupole mass filter via an arrayed detector. The linearity of the detected quadrupole ion current in combination with it reproducible spatial-temporal structure enables the deconvolution of the contributions of signals from individual ion species in complex mixtures where both sensitivity and mass resolving power are essential.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: September 23, 2014
    Assignee: Thermo Finnigan LLC
    Inventors: Alan E. Schoen, Robert A. Grothe
  • Mass spectrometry systems
    Patent number: 8598515
    Abstract: Described herein are methods that may be used related to mass spectrometry, such as mass spectrometry analysis, mass spectrometry calibration, identification of proteins/peptides by mass spectrometry and/or mass spectrometry data collection strategies. In one embodiment, the subject matter discloses a phase-modeling analysis method for identification of proteins or peptides by mass spectrometry.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: December 3, 2013
    Assignee: Cedars-Sinai Medical Center
    Inventor: Robert A. Grothe
  • Mass spectrometry systems
    Patent number: 8536521
    Abstract: Described herein are methods that may be used related to mass spectrometry, such as mass spectrometry analysis, mass spectrometry calibration, identification of proteins/peptides by mass spectrometry and/or mass spectrometry data collection strategies. In one embodiment, the subject matter discloses a phase-modeling analysis method for identification of proteins or peptides by mass spectrometry.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: September 17, 2013
    Assignee: Cedars-Sinai Medical Center
    Inventor: Robert A. Grothe
  • Mass spectrometry systems
    Patent number: 8502137
    Abstract: Described herein are methods that may be used related to mass spectrometry, such as mass spectrometry analysis, mass spectrometry calibration, identification of proteins/peptides by mass spectrometry and/or mass spectrometry data collection strategies. In one embodiment, the subject matter discloses a phase-modeling analysis method for identification of proteins or peptides by mass spectrometry.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: August 6, 2013
    Assignee: Cedars-Sinai Medical Center
    Inventor: Robert A. Grothe
  • Mass spectrometry systems
    Patent number: 8399827
    Abstract: Described herein are methods that may be used related to mass spectrometry, such as mass spectrometry analysis, mass spectrometry calibration, identification of proteins/peptides by mass spectrometry and/or mass spectrometry data collection strategies. In one embodiment, the subject matter discloses a phase-modeling analysis method for identification of proteins or peptides by mass spectrometry.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: March 19, 2013
    Assignee: Cedars-Sinai Medical Center
    Inventor: Robert A. Grothe