Patents by Inventor Robert A. Howd

Robert A. Howd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aldoxime-substituted imidazolium derivatives useful in the treatment of poisoning by phosphorus-containing chemicals
    Patent number: 4925856
    Abstract: A therapeutically effective class of low toxicity aldoxime-substituted functionalized imidazolium compounds and compositions is disclosed which is effective in the treatment of living species poisoned by organophosphorus chemicals which inactivate the enzyme acetylcholinesterase. In vivo administration of therapeutically effective amounts of these aldoxime-substituted imidazolium derivatives has been found to save mammals having inhibited acetylcholinesterase due to injection with lethal dosages of Soman.
    Type: Grant
    Filed: April 19, 1989
    Date of Patent: May 15, 1990
    Assignee: SRI International
    Inventors: Ralph N. Harris, III, Clifford D. Bedford, Dane A. Goff, Duane E. Hilmas, Robert A. Howd, Richard A. Kenley, Gary A. Koolpe, Robert O. Pick
  • Aldoxime-substituted triazolium compounds useful in the treatment of poisoning by phosphorus-containing chemicals
    Patent number: 4865837
    Abstract: A therapeutically effective class of low toxicity aldoxime-substituted trazolium derivatives is disclosed which is effective in the treatment of living species poisoned by organophosphorus chemicals which inactivate the enzyme acetylcholinesterase. In vivo administration of therapeutically effective amounts of these low toxicity aldoxime-substituted triazolium derivatives has been found to save mice having inhibited acetylcholinesterase due to injection with lethal dosages of Soman.
    Type: Grant
    Filed: July 28, 1987
    Date of Patent: September 12, 1989
    Assignee: SRI International
    Inventors: Ralph N. Harris, III, Clifford D. Bedford, Duane E. Hilmas, Robert A. Howd, Richard A. Kenley, Gary A. Koolpe