Abstract: The systems, devices and methods provide customizable and adjustable support to anatomical tissue or organs, such as pelvic, vaginal, uterine, cervical, bladder, rectal, among others, or any combination thereof. The anatomical support device may include a support member having a periphery that surrounds an opening. The support member may be configured to releasably and adjustably expand between one or more expanding states from a resting state and contract to the resting state. The support member may include a first portion and a second portion disposed along the periphery. Each portion may include a passage cross-sectional area and a wall thickness. The first wall thickness and/or the first passage cross-sectional area of the first portion may be different from the second wall thickness and/or the second passage cross-sectional area of the second portion.

Abstract: A roller with a plastic injection tube to coat the steel shaft wherein the plastic coated shaft eliminates the metal-to-metal contact that creates the noise. Closing the gap between the metal roller shaft and hinge barrel will eliminate the metal-to-metal contact resulting in a very quiet, rolling garage door. Further disclosed is an improved roller wheel having a tire made of material selected from the group consisting of urethane and urethane (PER) on which the roller will roll within a garage door track to significantly reduce the noise of the roller as it rolls inside the garage door tracks as the garage door is raised and lowered. The improved wheel include two plastic wheel sections with a gap therebetween with the tire made of urethane (PER) molded between the two sections and also extending through openings within the two wheel sections to retain the two wheel sections together.

Abstract: A roller with a plastic injection tube to coat the steel shaft wherein the plastic coated shaft eliminates the metal-to-metal contact that creates the noise. Further disclosed is an improved roller wheel having a tire made of material selected from the group consisting of urethane and urethane (PER) on which the roller will roll within a garage door track to significantly reduce the noise of the roller as it rolls inside the garage door tracks as the garage door is raised and lowered. The roller shaft has the treads extending to a distal end of the roller shaft where a plastic washer and a closing cover nut with interior threads are threaded onto the distal end of the roller shaft. The closing cover nut with interior threads is selected from an acorn nut with a nylon insert and a hex lock nut with a nylon insert.

Abstract: Steel garage door decorations made out of powder coated aluminum. The decorations include a decorative hinge, a decorative barn door handle, a decorative knocker assembly and a decorative clavo. Each of the garage door decorations is made out of powder coated aluminum and retains at least one concealed permanent magnet by which the decoration is temporarily affixed to a garage door panel. Each decoration also contains at least one recess where adhesive can be applied after the proper orientation and location of each respective garage door decoration have been finalized.

Abstract: An apparatus and method for forming new and novel portions of a garage door panel. This includes forming at least one decoration into a steel plate section and bonding to it a unique foam core where a mirror image decoration is routed into the foam core to exactly match the decoration. In addition, an aluminum diamond plate sheet with a front surface and a rear surface is bonded to the rear of the foam core. The aluminum diamond plate sheet also includes a sheet of steel affixed to its rear surface which rear surface is bonded to the foam core so that magnetic decorations can be attached to the front of the aluminum diamond plate sheet.

Abstract: A roller with a plastic injection tube to coat the steel shaft wherein the plastic coated shaft eliminates the metal-to-metal contact that creates the noise. Further disclosed is an improved roller wheel having a tire made of material selected from the group consisting of urethane and urethane (PER) on which the roller will roll within a garage door track to significantly reduce the noise of the roller as it rolls inside the garage door tracks as the garage door is raised and lowered. The roller shaft has the treads extending to a distal end of the roller shaft where a plastic washer and a closing cover nut with interior threads are threaded onto the distal end of the roller shaft. The closing cover nut with interior threads is selected from an acorn nut with a nylon insert and a hex lock nut with a nylon insert.

Abstract: Disclosed herein is a trash collection device. In some embodiments, the trash collection device is placed under a seat and multiple bags are available. By having multiple bags available, the amount of time for cleanup is reduced by not having to clean trash off the ground and by not having to replace bags after every use.

Abstract: The systems, devices and methods provide customizable and adjustable support to anatomical tissue or organs, such as pelvic, vaginal, uterine, cervical, bladder, rectal, among others, or any combination thereof. The anatomical support device may include a support member having a periphery that surrounds an opening. The support member may be configured to releasably and adjustably expand between one or more expanding states from a resting state and contract to the resting state. The support member may include a first portion and a second portion disposed along the periphery. Each portion may include a passage cross-sectional area and a wall thickness. The first wall thickness and/or the first passage cross-sectional area of the first portion may be different from the second wall thickness and/or the second passage cross-sectional area of the second portion.

Abstract: A nontoxic liquid dye formulation for color staining the skin of live angling bait species comprises a dye substance suitable for application, and thereby for imparting color, to skin of angling bait species. The dye substance has a pH of between about 5.8 and about 8.2 and has a dye molecular structure carrying a net charge of no more than two negative charges or a net charge of no more than one positive charge. A dye carrier for the dye substance includes a water-soluble polyether compound mixed in an aqueous solution. The polyether compound has a weight average molecular weight of between about 2,000 and about 6,000 to function as a phase transfer agent that promotes partitioning of components of the dye substance into the skin of the bait species. The water soluble dye remains in the skin of the bait species, even though it is in an oily environment.

Abstract: An apparatus for a garage door panel which includes a formed metal section with at least one decorative portion on the front surface and having a rear surface. The formed metal section including a top portion with a male tongue and a bottom portion with a female groove. The garage door panel includes an insert combination of a polystyrene section and twin wall polypropylene section. The rear surface of the formed metal section is spray coated with a combination isocyanate and polyol resin which combines to form as hardened polyurethane foam section. The front surface of the polystyrene section is retained against the polyurethane foam section and the rear surface of the twin wall polypropylene serves as the rear surface of the garage door panel. Two metal stiles are respectively affixed at the left or first end and the right or second end.

Abstract: The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.

Abstract: A roller with a Delrin plastic injection to coat the steel shaft wherein the plastic coated shaft eliminates the metal-to-metal contact that creates the noise. The new and improved Delrin plastic coated shaft will be 1 mm larger than industry standard shafts because 10-11 mm industry standard shafts are too loose in the hinge barrels which allows the rattling. This improved roller shaft is 12 mm at finished thickness to reduce the extra space. A roller wheel connected to a roller shaft being a portion of a hinge affixed to a garage door, the roller wheel adapted to roll within a track of a garage door, the roller wheel including at least one ball bearing and a collar retained in a circumferential cylindrical middle cover seal and the circumferential cylindrical middle cover seal covered with a steel cover, the steel cover covered with 50-90 durometer soft urethane plastic.

Abstract: A roller with a Delrin plastic injection to coat the steel shaft wherein the plastic coated shaft eliminates the metal-to-metal contact that creates the noise. The new and improved Delrin plastic coated shaft will be 1 mm larger than industry standard shafts because 10-11 mm industry standard shafts are too loose in the hinge barrels which allows the rattling. This improved roller shaft is 12 mm at finished thickness to reduce the extra space. Closing the gap between the roller shaft and hinge barrel will eliminate the metal-to-metal contact resulting in a very quiet, rolling garage door. By keeping the finished thickness at 12 mm on the new shaft, the roller will still work on new and old garage door hinges and fixtures. This makes the new and improved roller shaft a truly universal product that will work on 90% of garage doors in service and almost all new models. This is a long over-due improvement to garage door rollers.

Abstract: A roller with a plastic injection tube to coat the steel shaft wherein the plastic coated shaft eliminates the metal-to-metal contact that creates the noise. Closing the gap between the metal roller shaft and hinge barrel will eliminate the metal-to-metal contact resulting in a very quiet, rolling garage door. Further disclosed is an improved roller wheel having a tire made of material selected from the group consisting of urethane and urethane (PER) on which the roller will roll within a garage door track to significantly reduce the noise of the roller as it rolls inside the garage door tracks as the garage door is raised and lowered. The improved wheel include two plastic wheel sections with a gap therebetween with the tire made of urethane (PER) molded between the two sections and also extending through openings within the two wheel sections to retain the two wheel sections together.

Abstract: Disclosed are systems and methods for estimating the vitreal half-life of a therapeutic agent. In particular, systems and methods are disclosed for predicting the vitreal half-life of a therapeutic agent conjugated to a polymer that make use of an empirically-derived relationship of vitreal half-life to the hydrodynamic radius of a candidate therapeutic agent-polymer conjugate. The present disclosure is further directed to the use of the systems and methods disclosed herein to design a candidate therapeutic agent-polymer conjugate with a preselected vitreal half-life.

Abstract: Disclosed herein is a trash collection device. In some embodiments, the trash collection device is placed under a seat and multiple bags are available. By having multiple bags available, the amount of time for cleanup is reduced by not having to clean trash off the ground and by not having to replace bags after every use.

Abstract: This invention is directed to materials and devices for sensing bio-potential signals from animals, particularly to sensing bio-potential signals to monitor humans in the medical field. In general, bio-potential sensors may be attached to the body of an animal, such as a human, in order to receive bio-potential signals such that information about the bioelectrical properties of the cells and/or tissues of the animal may be gathered. The bio-potential sensor may generally include a dry electrode that may be placed in contact with the skin of an animal to receive bio-potential signals from the animal. A dry electrode may generally include an electrically conductive solid material which may conduct electrical signals from an animal.

Abstract: The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.

Abstract: A roller with a Delrin plastic injection to coat the steel shaft wherein the plastic coated shaft eliminates the metal-to-metal contact that creates the noise. The new and improved Delrin plastic coated shaft will be 1 mm larger than industry standard shafts because 10-11 mm industry standard shafts are too loose in the hinge barrels which allows the rattling. This improved roller shaft is 12 mm at finished thickness to reduce the extra space. A roller wheel connected to a roller shaft being a portion of a hinge affixed to a garage door, the roller wheel adapted to roll within a track of a garage door, the roller wheel including at least one ball bearing and a collar retained in a circumferential cylindrical middle cover seal and the circumferential cylindrical middle cover seal covered with a steel cover, the steel cover covered with 50-90 durometer soft urethane plastic.

Abstract: A roller with a Delrin plastic injection to coat the steel shaft wherein the plastic coated shaft eliminates the metal-to-metal contact that creates the noise. The new and improved Delrin plastic coated shaft will be limn larger than industry standard shafts because 10-11 mm industry standard shafts are too loose in the hinge barrels which allows the rattling. This improved roller shaft is 12 mm at finished thickness to reduce the extra space. Closing the gap between the roller shaft and hinge barrel will eliminate the metal-to-metal contact resulting in a very quiet, rolling garage door. By keeping the finished thickness at 12 mm on the new shaft, the roller will still work on new and old garage door hinges and fixtures. This makes the new and improved roller shaft a truly universal product that will work on 90% of garage doors in service and almost all new models. This is a long over-due improvement to garage door rollers.