Patents by Inventor Robert A. Keyes

Robert A. Keyes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11236034
    Abstract: Provided is a process for preparing acrylic acid comprising (1) preparing acrolein by catalytic gas phase oxidation comprising (a) providing a reaction gas comprising (i) 5 to 10 mol % propylene, (ii) 0.02 to 0.75 mol % propane, and (iii) 0.25 to 1.9 mol % of a fuel mixture comprising at least one of methane and ethane, wherein the molar ratio of the total amount of propane, methane, and ethane to the total amount of propylene is from 0.01:1 to 0.25:1, (b) contacting the reaction gas with a first mixed metal oxide catalyst to form a mixture comprising acrolein, wherein the first mixed metal oxide catalyst comprises one or more of molybdenum, bismuth, cobalt, and iron, and (2) contacting the acrolein mixture with a second mixed metal oxide catalyst to form a mixture comprising acrylic acid, wherein the second mixed metal oxide catalyst comprises one or more of molybdenum, vanadium, tungsten, copper, and antimony.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: February 1, 2022
    Assignee: Rohm and Haas Company
    Inventors: Donald A. Ebert, Timothy Allen Hale, Brian Robert Keyes, Justin Rose, Jinsuo Xu
  • Patent number: 11078147
    Abstract: Provided is a process for preparing acrolein by catalytic gas phase oxidation comprising (a) providing a reaction gas comprising (i) 5 to 10 mol % propylene, (ii) 0.02 to 0.75 mol % propane, and (iii) 0.25 to 1.9 mol % of a fuel mixture comprising at least one of methane and ethane, wherein the molar ratio of the total amount of propane, methane, and ethane to the total amount of propylene is from 0.01:1 to 0.25:1, and (b) contacting the reaction gas with a mixed metal oxide catalyst comprising one or more of molybdenum, bismuth, cobalt, and iron.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: August 3, 2021
    Assignee: Rohm and Haas Company
    Inventors: Donald A. Ebert, Timothy Allen Hale, Brian Robert Keyes, Justin Rose, Jinsuo Xu
  • Publication number: 20200407302
    Abstract: Provided is a process for preparing acrolein by catalytic gas phase oxidation comprising (a) providing a reaction gas comprising (i) 5 to 10 mol % propylene, (ii) 0.02 to 0.75 mol % propane, and (iii) 0.25 to 1.9 mol % of a fuel mixture comprising at least one of methane and ethane, wherein the molar ratio of the total amount of propane, methane, and ethane to the total amount of propylene is from 0.01:1 to 0.25:1, and (b) contacting the reaction gas with a mixed metal oxide catalyst comprising one or more of molybdenum, bismuth, cobalt, and iron.
    Type: Application
    Filed: February 21, 2019
    Publication date: December 31, 2020
    Inventors: Donald A. Ebert, Timothy Allen Hale, Brian Robert Keyes, Justin Rose, Jinsuo Xu
  • Publication number: 20200407306
    Abstract: Provided is a process for preparing acrylic acid comprising (1) preparing acrolein by catalytic gas phase oxidation comprising (a) providing a reaction gas comprising (i) 5 to 10 mol % propylene, (ii) 0.02 to 0.75 mol % propane, and (iii) 0.25 to 1.9 mol % of a fuel mixture comprising at least one of methane and ethane, wherein the molar ratio of the total amount of propane, methane, and ethane to the total amount of propylene is from 0.01:1 to 0.25:1, (b) contacting the reaction gas with a first mixed metal oxide catalyst to form a mixture comprising acrolein, wherein the first mixed metal oxide catalyst comprises one or more of molybdenum, bismuth, cobalt, and iron, and (2) contacting the acrolein mixture with a second mixed metal oxide catalyst to form a mixture comprising acrylic acid, wherein the second mixed metal oxide catalyst comprises one or more of molybdenum, vanadium, tungsten, copper, and antimony.
    Type: Application
    Filed: February 21, 2019
    Publication date: December 31, 2020
    Inventors: Donald A. Ebert, Timothy Allen Hale, Brian Robert Keyes, Justin Rose, Jinsuo Xu
  • Publication number: 20140288076
    Abstract: The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method of treating a disease or condition mediated by CDK9.
    Type: Application
    Filed: June 4, 2014
    Publication date: September 25, 2014
    Applicant: NOVARTIS AG
    Inventors: Paul A. Barsanti, Cheng Hu, Jeff Jin, Robert Keyes, Robert Kucejko, Xiaodong Lin, Yue Pan, Keith B. Pfister, Martin Sendzik, James Sutton, Lifeng Wan
  • Patent number: 8778951
    Abstract: The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method of treating a disease or condition mediated by CDK9.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: July 15, 2014
    Assignee: Novartis AG
    Inventors: Paul A. Barsanti, Cheng Hu, Jeff Jin, Robert Keyes, Robert Kucejko, Xiaodong Lin, Yue Pan, Keith B. Pfister, Martin Sendzik, James Sutton, Lifeng Wan
  • Patent number: 8415381
    Abstract: The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method of treating a disease or condition mediated by CDK9.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: April 9, 2013
    Assignee: Novartis AG
    Inventors: Paul A. Barsanti, Cheng Hu, Jeff Jin, Robert Keyes, Robert Kucejko, Xiaodong Lin, Yue Pan, Keith B. Pfister, Martin Sendzik, James Sutton, Lifeng Wan
  • Publication number: 20110028492
    Abstract: The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method of treating a disease or condition mediated by CDK9.
    Type: Application
    Filed: July 26, 2010
    Publication date: February 3, 2011
    Inventors: Paul A. Barsanti, Cheng Hu, Jeff Jin, Robert Keyes, Robert Kucejko, Xiaodong Lin, Yue Pan, Keith B. Pfister, Martin Sendzik, James Sutton, Lifeng Wan
  • Publication number: 20070219258
    Abstract: The present invention relates to compounds of formula (I) which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Application
    Filed: February 15, 2007
    Publication date: September 20, 2007
    Inventors: Robert Keyes, Yu Gu, Hing Sham
  • Publication number: 20070142353
    Abstract: Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
    Type: Application
    Filed: February 15, 2007
    Publication date: June 21, 2007
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Robert Keyes, Xenia Searle, Rolf Wagner
  • Publication number: 20060287356
    Abstract: The present invention relates to compounds that activate AMP-activated protein kinase (AMPK), including the preparation of the compounds, compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders such as diabetes, metabolic syndrome, and obesity.
    Type: Application
    Filed: August 24, 2006
    Publication date: December 21, 2006
    Inventors: Rajesh Iyengar, Andrew Judd, Gang Zhao, Philip Kym, Hing Sham, Yugui Gu, Gang Liu, Mei Liu, Hongyu Zhao, Richard Clark, Ernst Frevert, Barbara Cool, Tianyuan Zhang, Robert Keyes, Todd Hansen, Zhili Xin
  • Publication number: 20060178400
    Abstract: The present invention relates to compounds of formula (I), which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Application
    Filed: November 7, 2005
    Publication date: August 10, 2006
    Inventors: Bruce Beutel, Heidi Camp, Richard Clark, Yu-Gui Gu, Todd Hansen, Robert Keyes, Qun Li, Gang Liu, Hing Sham, Xiaojun Wang, Moshe Weitzberg, Zhili Xin, Xiangdong Xu, Tianyuan Zhang
  • Publication number: 20050159423
    Abstract: Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
    Type: Application
    Filed: January 21, 2004
    Publication date: July 21, 2005
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Robert Keyes, Xenia Searle, Rolf Wagner
  • Publication number: 20050056521
    Abstract: Apparatus and methods for unloading and binding brick or other components include an infeed conveyor that delivers layers of brick to a transfer distribution carriage. The distribution carriage repositions the brick layers on either an outfeed conveyor or a tine conveyor. The layers of bricks carried by the outfeed conveyor are moved to where a tine layer is positioned on their upper surface. The tine conveyor divides the bricks into an arrangement of rows spaced apart to define openings for receiving a lifting or moving member, so that when the tine layer is positioned in a completed stack , enables movement of the stack by a forklift or other suitable moving means. Additional layer or layers are then positioned on the tine row on a packaging conveyor so that completed stacks are delivered to a package station that binds the stack of bricks or other components into an integrated structure.
    Type: Application
    Filed: September 12, 2003
    Publication date: March 17, 2005
    Inventor: Robert Keyes
  • Publication number: 20050038068
    Abstract: The present invention relates to compounds that activate AMP-activated protein kinase (AMPK), including the preparation of the compounds, compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders such as diabetes, metabolic syndrome, and obesity.
    Type: Application
    Filed: May 17, 2004
    Publication date: February 17, 2005
    Inventors: Rajesh Iyengar, Andrew Judd, Gang Zhao, Philip Kym, Hing Sham, Yugui Gu, Gang Liu, Mei Liu, Hongyu Zhao, Richard Clark, Ernst Frevert, Barbara Cool, Tianyuan Zhang, Robert Keyes, Todd Hansen, Zhili Xin
  • Publication number: 20040014690
    Abstract: Compounds having activity against methicillin-resistant staphylococcus aureus (MRSA), the compounds having formula (I) 1
    Type: Application
    Filed: February 10, 2003
    Publication date: January 22, 2004
    Inventors: Zhenkun Ma, Stevan Djuric, Robert Keyes, Hong Yong
  • Publication number: 20030162729
    Abstract: Compounds having activity against methicillin-resistant staphylococcus aureus (MRSA), the compounds having formula (I) 1
    Type: Application
    Filed: February 13, 2002
    Publication date: August 28, 2003
    Inventors: Zhenkun Ma, Stevan Djuric, Robert Keyes, Hong Yong
  • Patent number: D242696
    Type: Grant
    Filed: October 2, 1975
    Date of Patent: December 14, 1976
    Inventor: Robert A. Keyes
  • Patent number: D274398
    Type: Grant
    Filed: July 21, 1982
    Date of Patent: June 26, 1984
    Inventor: Robert A. Keyes