Abstract: Apparatuses, systems, and techniques to indicate data dependencies. In at least one embodiment, one or more neural networks are used to generate one or more indicators of one or more data dependencies and one or more indicators of direction of the one or more data dependencies.

Abstract: The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

Abstract: A motion-assisted positioning arm for a medical procedure. The positioning arm includes a base, an arm coupled to the base, and an end effector coupled to the arm. The arm includes a plurality of arm segments. The arm includes a plurality of joints for connecting the arm segments. The end effector may be manipulable with six degrees of freedom in a task-coordinate space based on motion by at least one joint in the plurality of joints. The positioning arm includes a processor to: detect manipulation of and determine forces or torques acting on the end effector; determine a surgical mode for constraining movement of the end effector in the task-coordinate space; determine an end effector velocity based on the determined forces or torques and the surgical mode for moving end effector; and apply at least one joint space movement based on the end effector velocity.

Abstract: Systems and methods for designing, testing, and validating a robotic system for space are provided. A system includes: a robotic manipulator; a dynamic system emulator configured to simulate a motion behaviour response of a first space robotic system based on forces and moments measured by the first robotic manipulator during physical interaction of the first robotic manipulator with a second robotic manipulator emulating motion behaviour of a second space robotic system; an arm controller configured to generate a manipulator tip reference trajectory command based on the motion behaviour response simulated by the dynamic system emulator and provide the manipulator tip reference trajectory command to the robotic manipulator; and an arm mechanism in the robotic manipulator configured to track a trajectory based on the manipulator tip reference trajectory command, such that the robotic manipulator emulates motion behaviour of the first space robotic system.

Abstract: Approaches for training data set size estimation for machine learning model systems and applications are described. Examples include a machine learning model training system that estimates target data requirements for training a machine learning model, given an approximate relationship between training data set size and model performance using one or more validation score estimation functions. To derive a validation score estimation function, a regression data set is generated from training data, and subsets of the regression data set are used to train the machine learning model. A validation score is computed for the subsets and used to compute regression function parameters to curve fit the selected regression function to the training data set. The validation score estimation function is then solved for and provides an output of an estimate of the number additional training samples needed for the validation score estimation function to meet or exceed a target validation score.

Abstract: In various examples, estimating optimal training data set sizes for machine learning model systems and applications. Systems and methods are disclosed that estimate an amount of data to include in a training data set, where the training data set is then used to train one or more machine learning models to reach a target validation performance. To estimate the amount of training data, subsets of an initial training data set may be used to train the machine learning model(s) in order to determine estimates for the minimum amount of training data needed to train the machine learning model(s) to reach the target validation performance. The estimates may then be used to generate one or more functions, such as a cumulative density function and/or a probability density function, wherein the function(s) is then used to estimate the amount of training data needed to train the machine learning model(s).

Abstract: The present disclosure provides compositions comprising an opsin polypeptide and an arrestin polypeptide and their use thereof. Exemplary embodiments provide a composition including an opsin polypeptide, or an opsin polypeptide and an arrestin polypeptide, wherein at least one of the opsin or arrestin polypeptide comprises at least one mutation that increases a temporal resolution of the opsin polypeptide’s response to light. The opsin polypeptide and the arrestin polypeptide can be operably linked or separate. Additionally, use of said compositions for restoring retinal photosensitivity or treating a retinal degenerative condition is also provided.

Abstract: Audio devices comprise a housing, a first audio connection supported by the housing, a second audio connection supported by the housing, and a controller supported by the housing that is configured to receive an input audio signal via the first audio connection, combine the input audio signal with a sound bite to create an output audio signal, and transmit the output audio signal via the second audio connection. Audio systems comprise an audio device and software that directs a computing device to receive a user input and transmit a sound bite to the audio device responsive to receipt of the user input.

Abstract: A smoke detection assembly for indicating when organic material has been smoked in an area includes a decal that has an adhesive layer is integrated such that the decal can be adhered to a surface in a cab of a vehicle. A chemical reagent is provided and the chemical reagent is infused into the decal. The chemical reagent is chemically reactive with one or more chemicals that are unique to smoke from combustion of organic material. Moreover, the chemical reagent changes colors when the chemical reagent is exposed to airborne nicotine. In this way the chemical reagent can visually indicate when organic material has been smoked in the vehicle.

Abstract: A charging and storage cart can be configured to support and charge a plurality of electronic devices. The charging and storage cart can include a frame, a panel, a tray, a support bracket, and an extension. The panel can be secured to the frame and can include a body and plurality of apertures extending through the body. The support bracket can be coupled to the tray and can be configured to engage the panel to support the tray. The extension can be connected to the support bracket can be insertable into any aperture of the plurality of apertures to connect the tray to the body of the panel in any location as desired.

Abstract: A height adjustable device including a counterbalance mechanism configured to be affixed adjacent to a rear portion of a vertical support member, a worksurface configured to be affixed adjacent to a front portion of the vertical support member, and a mounting member configured to slidably couple the worksurface to the counterbalance mechanism; wherein a portion of the mounting member extends through an opening defined in the vertical support member.

Abstract: The present invention relates to methods of regulating G protein activity, and related methods for the treatment of therapeutic conditions, for example retinal degeneration, by transforming a cell with a bistable opsin to activate a G protein, and provide a phototransduction response.

Abstract: The present invention relates to an improved method of providing photoreceptor function to a cell, for example for use in the treatment of retinal degeneration. The present invention also relates to compositions and kits, in particular for use in such methods.

Abstract: A doctor blade is disclosed that includes a blade surface and at least one shaped feature that is formed of a polymeric material and is provided to assist in maintaining the doctor blade with a doctor blade holder.

Abstract: A height adjustable device including a counterbalance mechanism configured to be affixed adjacent to a rear portion of a vertical support member, a worksurface configured to be affixed adjacent to a front portion of the vertical support member, and a mounting member configured to slidably couple the worksurface to the counterbalance mechanism; wherein a portion of the mounting member extends through an opening defined in the vertical support member.

Abstract: A motion-assisted positioning arm for a medical procedure. The positioning arm includes a base, an arm coupled to the base, and an end effector coupled to the arm. The arm includes a plurality of arm segments. The arm includes a plurality of joints for connecting the arm segments. The end effector may be manipulable with six degrees of freedom in a task-coordinate space based on motion by at least one joint in the plurality of joints. The positioning arm includes a processor to: detect manipulation of and determine forces or torques acting on the end effector; determine a surgical mode for constraining movement of the end effector in the task-coordinate space; determine an end effector velocity based on the determined forces or torques and the surgical mode for moving end effector; and apply at least one joint space movement based on the end effector velocity.

Abstract: A height adjustable device including a counterbalance mechanism configured to be affixed adjacent to a rear portion of a vertical support member, a worksurface configured to be affixed adjacent to a front portion of the vertical support member, and a mounting member configured to slidably couple the worksurface to the counterbalance mechanism; wherein a portion of the mounting member extends through an opening defined in the vertical support member.

Abstract: The present invention relates to an improved method of providing photoreceptor function to a cell, for example for use in the treatment of retinal degeneration. The present invention also relates to compositions and kits, in particular for use in such methods.

Abstract: A motion-assisted positioning arm for a medical procedure. The positioning arm includes a base, an arm coupled to the base, and an end effector coupled to the arm. The arm includes a plurality of arm segments. The arm includes a plurality of joints for connecting the arm segments. The end effector may be manipulable with six degrees of freedom in a task-coordinate space based on motion by at least one joint in the plurality of joints. The positioning arm includes a processor to: detect manipulation of and determine forces or torques acting on the end effector; determine a surgical mode for constraining movement of the end effector in the task-coordinate space; determine an end effector velocity based on the determined forces or torques and the surgical mode for moving end effector; and apply at least one joint space movement based on the end effector velocity.

Abstract: A charging and storage cart can be configured to support and charge a plurality of electronic devices. The charging and storage cart can include a frame, a panel, a tray, a support bracket, and an extension. The panel can be secured to the frame and can include a body and plurality of apertures extending through the body. The support bracket can be coupled to the tray and can be configured to engage the panel to support the tray. The extension can be connected to the support bracket can be insertable into any aperture of the plurality of apertures to connect the tray to the body of the panel in any location as desired.