Abstract: Methods for making, identifying, isolating and/or making binding proteins that contain an immunoglobulin light chain variable domain, including a somatically hypermutated light chain variable domain, fused with a heavy chain constant region, are provided. Exemplary binding proteins specific to small molecules are also provided.

Abstract: A block, block system and method of making a wall block. A block with multiple embodiments of a visually exposed surface having three dimensional shaped areas and three dimensional angular valleys or joints that can be used to construct a patio, wall, fence or the like; the multiple embodiments creating a more random and natural appearance. A mold box having a moveable liner and a stripper shoe that impart three dimensional shaped areas and three dimensional angular valleys or joints onto an exposed surface of a block. The moveable liner and stripper shoe also impart a parting line onto the exposed surface of the block.

Abstract: A computer-implemented method for authenticating a user device via a device credential scoped to a common domain shared among a plurality of payment networks may be provided. The method may include receiving, by a server of a payment network, a first request redirected from a sub-domain assigned to the payment network to a domain name associated with the payment network, responsive to the first request, transmitting, to the user device, an authentication request comprising a challenge, a user identifier that identifies the user, and the common domain to which the device credential is scoped, receiving, from the user device, a response, accessing the device credential, the device credential having been stored by the payment network, validating the response based on the device credential, and causing, by the server, the user identifier and the device credential to be federated to the other ones of the plurality of payment networks based on the validating.

Abstract: The present invention relates to shaker doors with solid cores and methods for making the same. The shaker doors contain different core materials at the recessed panel than the raise peripheral region to provide dimensional stability and reduced distortion when the doors are exposed to high humidity. The devices and methods also provide for easy assembly of solid core shaker doors, including fire rated doors.

Abstract: Systems and methods for providing compliance indicators for API specifications are disclosed. In accordance with aspects, a method may include receiving, at a deployment pipeline, an application programming interface (API) specification; parsing, by a validation engine, the API specification to determine an API service or protocol for which the API adheres to; parsing, by the validation engine, the API specification to determine a data schema included in the API specification; performing, by the validation engine, a search of a domain dictionary using information in the data schema as a search parameter; determining, by the validation engine and based on the search, a data model included in the domain dictionary, wherein the data model and the data schema correspond; and determining, by the validation engine, a compliance score of the data schema, wherein the compliance score is based on a comparison the data schema with the data model.

Abstract: Provided is a method for manufacturing photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby. The method comprises: (a) providing a mold assembly comprised of a base curve and a front curve, the base curve and the front curve defining and enclosing a cavity therebetween, the cavity containing a reactive mixture, wherein the reactive mixture comprises at least one polymerizable monomer, a photoinitiator which absorbs at an activating wavelength, and a photoabsorbing compound which displays absorption at the activating wavelength; and (b) curing the reactive mixture to form the photoabsorbing contact lens by exposing the reactive mixture to radiation that includes the activating wavelength, wherein the radiation is directed at both the base curve and the front curve of the mold assembly, and wherein the radiation's radiant energy at the base curve is greater than the radiation's radiant energy at the front curve.

Abstract: A method of determining solar radiation exposure at a predetermined location is provided. The method may include generating a first two-dimensional (2D) matrix including a plurality of elements, wherein each element of the plurality of elements of the first 2D matrix includes an elevation/azimuth pair representing a light ray extending from the predetermined location to one or more positions in the sky. The method may further include generating a second 2D matrix including a plurality of elements, wherein each index of the second 2D matrix includes an associated elevation/azimuth pair of the first 2D matrix. Each element of the plurality of elements of the second 2D matrix represents an amount of solar radiation to impinge on the predetermined location from a direction of a respective elevation/azimuth pair.

Abstract: Provided is a method for manufacturing photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby. The method comprises: (a) providing a mold assembly comprised of a base curve and a front curve, the base curve and the front curve defining and enclosing a cavity therebetween, the cavity containing a reactive mixture, wherein the reactive mixture comprises at least one polymerizable monomer, a photoinitiator which absorbs at an activating wavelength, and a photoabsorbing compound which displays absorption at the activating wavelength; and (b) curing the reactive mixture to form the photoabsorbing contact lens by exposing the reactive mixture to radiation that includes the activating wavelength, wherein the radiation is directed at both the base curve and the front curve of the mold assembly, and wherein the radiation's radiant energy at the base curve is greater than the radiation's radiant energy at the front curve.

Abstract: A block, block system and method of making a wall block. A block with multiple embodiments of a visually exposed surface having three dimensional shaped areas and three dimensional angular valleys or joints that can be used to construct a patio, wall, fence or the like; the multiple embodiments creating a more random and natural appearance. A mold box having a moveable liner and a stripper shoe that impart three dimensional shaped areas and three dimensional angular valleys or joints onto an exposed surface of a block. The moveable liner and stripper shoe also impart a parting line onto the exposed surface of the block.

Abstract: A block, block system and method of making a wall block. A block with multiple embodiments of a visually exposed surface having three dimensional shaped areas and three dimensional angular valleys or joints that can be used to construct a patio, wall, fence or the like; the multiple embodiments creating a more random and natural appearance. A mold box having a moveable liner and a stripper shoe that impart three dimensional shaped areas and three dimensional angular valleys or joints onto an exposed surface of a block. The moveable liner and stripper shoe also impart a parting line onto the exposed surface of the block.

Abstract: A microscope can be retrofitted with a nosepiece configured with a miniaturized inertial measurement sensor and an associated wireless transmitter that functions to relay information as to the current position of the nosepiece as determined by the inertial measurement sensor thereby indicating which objective lens is in the optical path to an external computing device. Alternatively, the nosepiece can configured with a miniaturized inertial measurement sensor generating an electrical signal indicating the current position of the nosepiece or equivalently the current objective lens in the optical path, and a cable for carrying power to the sensor, the electrical signal to internal electronics of the microscope, or both. This latter configuration is suitable in the situation where the microscope is configured with this arrangement, as manufactured.

Abstract: The present invention relates to a method for enhancing crop performance in Brassica, the method comprising providing Brassica seeds which have been sorted so that at least 90% of the seed population have a seed diameter of at least 1.7 mm; and seeding said Brassica seeds at a seeding rate sufficient to establish a population of Brassica plants so that the plants have a density of 40 to 95 plants per m2 when the plants are at any one or more of phenological growth stages 11, 12, 13, 14, or 15, according to the BBCH scale; and that the plants show an establishment rate of at least 40%.

Abstract: Systems and methods for enhanced organizational transparency using a credit chain are disclosed. In one embodiment, a method for accessing a resource may include (1) a cloud foundry comprising at least one computer processor receiving an application request from an interface provided by an end user electronic device; (2) the cloud foundry determining a location of at least one resource associated with the application request, wherein the location is selected from a private cloud and a public cloud; (3) the cloud foundry retrieving at least one of a microservice and an API necessary to access the resource from the location; and (4) the cloud foundry routing the application request to the location using the at least one of the microservice and the API.

Abstract: A landscaping block having a block body with at least a first side surface, a second side surface, a third side surface and a fourth side surface, and opposed and substantially parallel top and bottom surfaces. The patio block having at least one spacer projection extending outwardly from each of the at least first, second, third and fourth side surfaces. The patio block having at least one spacer locator positioned along each one of the first, second, third and fourth side surfaces. The at least one spacer locator positioned along each side surface has a retaining surface shaped to receive a spacer projection, at least a portion of the retaining surface extending outwardly from the side surface.

Abstract: Wall blocks, veneers, veneer connectors, walls, and methods of constructing walls are provided. More particularly, the invention relates to constructing walls in which a veneer panel is attached to a wall block with a connector and in which the front faces of the veneers have a desirable texture.

Abstract: Wall blocks, veneers, veneer connectors, walls, and methods of constructing walls are provided. More particularly, the invention relates to constructing walls in which a veneer panel is attached to a wall block with a connector and in which the front faces of the veneers have a desirable texture.

Abstract: An apparatus and system for generating pressure pulses for enhancing and completing a well bore within a pipe or coiled tubing operation including: a valve longitudinally and axially positioned within the center of a pulser section, a gearbox, and an impeller. The main fluid flow is interrupted by the main valve which is operated by a controlled pilot fluid stream. The pilot fluid stream is controlled by a determined rotation of a gearbox driven by an impeller located centrally and axially and connected to the gearbox. Most specifically, the system utilizes pulse technology to improve weight transfer in horizontal wells by modulating flow, pressure and weight on the bit. The system can be used to overcome coiled tubing (CT) drill out challenges by overcoming friction forces that impede the downhole reach.

Abstract: A method of determining solar radiation exposure at a predetermined location is provided. The method may include generating a first two-dimensional (2D) matrix including a plurality of elements, wherein each element of the plurality of elements of the first 2D matrix includes an elevation/azimuth pair representing a light ray extending from the predetermined location to one or more positions in the sky. The method may further include generating a second 2D matrix including a plurality of elements, wherein each index of the second 2D matrix includes an associated elevation/azimuth pair of the first 2D matrix. Each element of the plurality of elements of the second 2D matrix represents an amount of solar radiation to impinge on the predetermined location from a direction of a respective elevation/azimuth pair.

Abstract: Provided is a method for manufacturing photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby. The method comprises: (a) providing a mold assembly comprised of a base curve and a front curve, the base curve and the front curve defining and enclosing a cavity therebetween, the cavity containing a reactive mixture, wherein the reactive mixture comprises at least one polymerizable monomer, a photoinitiator which absorbs at an activating wavelength, and a photoabsorbing compound which displays absorption at the activating wavelength; and (b) curing the reactive mixture to form the photoabsorbing contact lens by exposing the reactive mixture to radiation that includes the activating wavelength, wherein the radiation is directed at both the base curve and the front curve of the mold assembly, and wherein the radiation's radiant energy at the base curve is greater than the radiation's radiant energy at the front curve.

Abstract: A landscaping block having a block body with at least a first side surface, a second side surface, a third side surface and a fourth side surface, and opposed and substantially parallel top and bottom surfaces. The patio block having at least one spacer projection extending outwardly from each of the at least first, second, third and fourth side surfaces. The patio block having at least one spacer locator positioned along each one of the first, second, third and fourth side surfaces. The at least one spacer locator positioned along each side surface has a retaining surface shaped to receive a spacer projection, at least a portion of the retaining surface extending outwardly from the side surface.