Abstract: Provided herein are recombinant nucleic acids encoding a T cell receptor (TCR) fusion protein (TFP) and an interleukin-15 (IL-15) polypeptide and/or an interleukin-15 receptor alpha (IL-15R?) polypeptide, modified T cells expressing the encoded molecules, and methods of use thereof for the treatment of diseases, including cancer.

Abstract: A method for making an antimicrobial composite film can include forming a first coating layer by applying a first coating material on a substrate and forming a second coating layer by applying a second coating material on the first coating layer. The first coating material can comprise a first resin. The second coating material can comprise an antimicrobial material in a second resin or a dispersion. The first coating material can have a lower concentration of the antimicrobial material than the second coating material. The first and second coating layers can cooperatively define a composite film. The antimicrobial material can be asymmetrically dispersed in the composite film such that the antimicrobial material is concentrated closer to the outer surface of the composite film than to the inner surface of the composite film.

Abstract: A wireless actuator assembly for use in a building control system includes an actuated component such as a damper or a valve and an actuator that is configured to move the actuated component between a first position and a second position. The assembly includes a short range wireless communication module having a nominal communication range of less than 60 feet and an actuator controller that is operably coupled to the actuator and the short range wireless communication module. The actuator controller may be configured to receive one or more actuator commands from a portable handheld device via the short range wireless communication module and to send information to the portable handheld device via the short range wireless communication module.

Abstract: Systems and methods for using stratigraphic heat maps to steer a well being drilled. Data from one or more offset wells can be provided to a computer system and used with data from a well being drilled to generate one or more stratigraphic heat maps during the drilling of the subject well. The stratigraphic heat maps can be displayed and used to determine the location of the wellbore relative to one or more geological formations, including one or more target formations or within a target formation. Based on the use of the heat maps and the location of the wellbore relative to a target, the drill plan can be adjusted or updated and/or one or more drilling parameters or operations may be adjusted to drill the wellbore, such as to drill the wellbore to the target or to maximize the length of the wellbore within a target zone.

Abstract: A mobile device for determining a handling condition of the mobile device and a method of use thereof. One embodiment of the mobile device includes: at least one left capacitive proximity sensor disposed on a left side of the mobile device and operable to detect a hold condition, at least one right capacitive proximity sensor disposed on a right side of the mobile device and operable to detect a hold condition, an accelerometer disposed in the mobile device and operable to detect an orientation of the mobile device, an ambient light proximity sensor disposed in the mobile device and operable to detect a proximity of a user's head, and a processor operable to execute an application configured to gain access to and employ the hold condition, the orientation, and the proximity of the user's head to determine a handling condition.

Abstract: Systems and methods for automated filtering and normalization of logging data for improved drilling performance may enable smoothing and amplitude scaling of log data for meaningful comparison and analysis without scaling artefacts. The logging data may be collected from downhole sensors or may be recorded by a control system used for drilling. A computer implemented method may enable industrial scale automated filtering and normalization of logging data, including calibration to a known standard. In particular, the filtering and normalization may be used for stratigraphic analysis to correlate true vertical depth to measured depth along a wellbore.

Abstract: Polymer-based portions comprise an index of refraction ranging from about 1.49 to about 1.55. In some embodiments, the polymer-based portion comprises the product of curing 45-75 wt % of a difunctional urethane-acrylate oligomer with 25-55 wt % of a difunctional cross-linking agent and optionally a reactive diluent. In some embodiments, the polymer-based portion comprises the product of curing 75-100 wt % of a reactive diluent and optionally one or more a difunctional urethane-acrylate oligomer and/or a difunctional cross-linking agent. Adhesives comprise an index of refraction ranging from about 1.49 to about 1.55. In some embodiments, the adhesive comprises the product of heating 10-35 wt % of a silane-hydride-terminated siloxane and 65-90 wt % of a vinyl-terminated siloxane. In some embodiments, the adhesive comprises the product of irradiating a thiol-containing siloxane and a photo-initiator with at least one wavelength of light that the photo-initiator is sensitive to.

Abstract: Systems and methods are provided for measuring data set quality by applying Machine Learning (ML) to the data set, identifying good/bad records therein, and further identifying or scoring the records and data sets reflecting whether or not they are good or bad. Knowledge of the goodness or badness of the records of the data sets may enable a user to make determinations or take actions according to the records or data set with respect to further analytics based on the records. Use of an ML model may help avoid problems that arise when trying to manually monitor/classify records or generate code to decide if a record is good or bad in view of multi-field interdependencies. Moreover, training the ML model to compensate for new rules may be less complex than trying to manually account for or generate code to account for such new rules.

Abstract: The present disclosure is directed to pharmaceutical packages that include a coating that comprises polysilazane, and methods for the production of such. In one or more embodiments of the present disclosure, a pharmaceutical package may include a glass container comprising a first surface and a second surface opposite the first surface. The first surface may be an outer surface of the glass container. The pharmaceutical package may further include a coating positioned over at least a portion of the first surface of the glass container. The coating may include polysilazane.

Abstract: Optically transparent fiber glass cover substrates for electronic displays. The cover substrates include an optically transparent fiberglass composite layer including a fiberglass layer embedded in a matrix material and an optically transparent hard-coat layer bonded to a top surface of the optically transparent fiberglass composite layer. A bottom surface of the optically transparent fiberglass composite layer may define a bottommost exterior surface of a cover substrate. The bottommost exterior surface of a cover substrate may be disposed over a display surface of an electronic display to protect the display surface from damage.

Abstract: Systems and methods for automated filtering and normalization of logging data for improved drilling performance may enable smoothing and amplitude scaling of log data for meaningful comparison and analysis without scaling artefacts. The logging data may be collected from downhole sensors or may be recorded by a control system used for drilling. A computer implemented method may enable industrial scale automated filtering and normalization of logging data, including calibration to a known standard. In particular, the filtering and normalization may be used for stratigraphic analysis to correlate true vertical depth to measured depth along a wellbore.

Abstract: Described herein are articles and methods of making articles, including a transparent composite film having a fiber filler embedded in a polymer network. The polymer network of the transparent composite film is a cured, cross-linked matrix including a first and second structure segment. The structure segments may contribute or impart improved properties in the transparent composite film. The select structure segments can provide increased modulus and reduced glass transition temperature thereby allowing for a desirable balance of flexibility and rigidity in the transparent composite film. The improved transparent composite film is suitable for many applications including use in display devices.

Abstract: Described herein are articles and methods of making articles, including a transparent composite film having a fiber filler embedded in a polymer network and further including a hard coating. The polymer network of the film is a cured, cross-linked matrix. The hard coating is a cross-linked aromatic urethane acrylate oligomer and a photoinitiator and provides a flexible protective layer that maintains good hardness, puncture-resistance and scratch-resistance.

Abstract: A mobile device for determining a handling condition of the mobile device and a method of use thereof. One embodiment of the mobile device includes: at least one left capacitive proximity sensor disposed on a left side of the mobile device and operable to detect a hold condition, at least one right capacitive proximity sensor disposed on a right side of the mobile device and operable to detect a hold condition, an accelerometer disposed in the mobile device and operable to detect an orientation of the mobile device, an ambient light proximity sensor disposed in the mobile device and operable to detect a proximity of a user's head, and a processor operable to execute an application configured to gain access to and employ the hold condition, the orientation, and the proximity of the user's head to determine a handling condition.

Abstract: Polymer-based portions comprise an index of refraction ranging from about 1.49 to about 1.55. In some embodiments, the polymer-based portion comprises the product of curing 45-75 wt % of a difunctional urethane-acrylate oligomer with 25-55 wt % of a difunctional cross-linking agent and optionally a reactive diluent. In some embodiments, the polymer-based portion comprises the product of curing 75-100 wt % of a reactive diluent and optionally one or more a difunctional urethane-acrylate oligomer and/or a difunctional cross-linking agent. Adhesives comprise an index of refraction ranging from about 1.49 to about 1.55. In some embodiments, the adhesive comprises the product of heating 10-35 wt % of a silane-hydride-terminated siloxane and 65-90 wt % of a vinyl-terminated siloxane. In some embodiments, the adhesive comprises the product of irradiating a thiol-containing siloxane and a photo-initiator with at least one wavelength of light that the photo-initiator is sensitive to.

Abstract: A system comprising an energy storage device including a plurality of cells and a sensor per cell to provide the voltage of each cell; and a device to read the voltages of each cell, calculate a correlation between the voltages of each cell, store a result of the calculation, and set a threshold for the result, wherein in response to the result meeting the threshold, the device to send a notification including a message stating a potential failure of the energy storage device.

Abstract: A mobile device for determining a handling condition of the mobile device and a method of use thereof. One embodiment of the mobile device includes: at least one left capacitive proximity sensor disposed on a left side of the mobile device and operable to detect a hold condition, at least one right capacitive proximity sensor disposed on a right side of the mobile device and operable to detect a hold condition, an accelerometer disposed in the mobile device and operable to detect an orientation of the mobile device, an ambient light proximity sensor disposed in the mobile device and operable to detect a proximity of a user's head, and a processor operable to execute an application configured to gain access to and employ the hold condition, the orientation, and the proximity of the user's head to determine a handling condition.

Abstract: Systems and methods for automated filtering and normalization of logging data for improved drilling performance may enable smoothing and amplitude scaling of log data for meaningful comparison and analysis without scaling artefacts. The logging data may be collected from downhole sensors or may be recorded by a control system used for drilling. A computer implemented method may enable industrial scale automated filtering and normalization of logging data, including calibration to a known standard. In particular, the filtering and normalization may be used for stratigraphic analysis to correlate true vertical depth to measured depth along a wellbore.

Abstract: Optically transparent fiber glass cover substrates for electronic displays. The cover substrates include an optically transparent fiberglass composite layer including a fiberglass layer embedded in a matrix material and an optically transparent hard-coat layer bonded to a top surface of the optically transparent fiberglass composite layer. A bottom surface of the optically transparent fiberglass composite layer may define a bottommost exterior surface of a cover substrate. The bottommost exterior surface of a cover substrate may be disposed over a display surface of an electronic display to protect the display surface from damage.

Abstract: The present disclosure is directed to pharmaceutical packages that include a coating that comprises polysilazane, and methods for the production of such. In one or more embodiments of the present disclosure, a pharmaceutical package may include a glass container comprising a first surface and a second surface opposite the first surface. The first surface may be an outer surface of the glass container. The pharmaceutical package may further include a coating positioned over at least a portion of the first surface of the glass container. The coating may include polysilazane.