Abstract: A sensor used to sense the position of an attached movable object. The sensor can be mounted to a pneumatic actuator. The sensor includes a housing that has a pair of cavities or pockets separated by a wall. A magnet carrier is positioned within one of the cavities and a magnet is coupled to the magnet carrier. The magnet carrier is coupled to the moveable object. A magnetic sensor is positioned in the other of the cavities. The magnetic sensor generates an electrical signal that is indicative of a position of the movable object.

Abstract: A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment with a cardiac glycoside in a disease having an etiology associated with excessive cell proliferation. The kit and assay are used to determine the ratio of isoforms of the ? subunit of Na, K-ATPase obtained from the diseased cell or tissue. The kit can be used to predict the therapeutic responsiveness of cancer or tumor in a subject to treatment with a cardiac glycoside. The kit and assay can be incorporated in a method of treating a disease or disorder having an etiology associated with excessive cell proliferation with a composition comprising a cardiac glycoside.

Abstract: A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside to a subject. The cardiac glycoside can be present in a dosage form.

Abstract: An improved aluminum-boron carbide (ABC) composite has been discovered that is comprised of a continuous network of AlB24C4 and boron carbide grains having therein other isolated aluminum-boron carbide reactive phases and at most 2% by volume of isolated metal. The improved ABC composite may be formed by forming boron carbide particulates into a porous body that has a porosity of at most about 35%, where the boron particulates have been heat treated to a temperature of 1200° C. to 1800° C., infiltrating the porous body with aluminum or aluminum alloy until an infiltrated aluminum-boron carbide body is formed that has at most about 1% porosity, heat treating the infiltrated body for at least 25 hours at 1000° C. to 1100° C. to form an aluminum boron carbide composite having a continuous network of AlB24C4 and boron carbide, and subsequently heat-treating to 700° C. to 900° C. to form the improved aluminum boron carbide composite.

Abstract: A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside to a subject. The cardiac glycoside can be present in a dosage form.

Abstract: A method of providing information to a user via a printed substrate. The substrate chas a graphic image and coded data indicative of a region identity associated with the substrate and of a plurality of locations on the substrate. The method includes the steps of: (i) receiving interaction data indicative of the region identity and a position of a sensing device relative to the image; (ii) identifying and retrieving a page description corresponding to the printed substrate using the region identity; (iii) generating a query expression including search terms; (iv) forming a request using the query expression; and sending the request to the user. At least one of the search terms is associated, in the page description, with a zone of the graphic image containing the position of the sensing device.

Abstract: Disclosed is a form-fitting glove and catching device that provides sports fans with a ready means to catch a ball entering the spectator seating area while not reducing the wearer's ability to handle items will the glove is worn. The device comprises a glove having a body region covering the palm region and backside region of the wearer's hand, a thumb portion, a forefinger portion and a plurality of shortened finger portions. Spanning between the thumb and forefinger portions is a mitt web material for accepting a baseball or similar sports ball therein. The palm region includes a layer of protective padding, while the base of the body region comprises an opening having a strap securement means. The mitt web is a woven or netted material being secured along its periphery to the exterior portion of the thumb portion and forefinger, or alternatively to the thumb portion and middle finger.

Abstract: A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of cardiac glycoside to a subject. The cardiac glycoside can be present in a dosage form.

Abstract: A sensor used to sense the position of an attached movable object. The sensor can be mounted to a pneumatic actuator. The sensor includes a housing that has a pair of cavities or pockets separated by a wall. A magnet carrier is positioned within one of the cavities and a magnet is coupled to the magnet carrier. The magnet carrier is coupled to the moveable object. A magnetic sensor is positioned in the other of the cavities. The magnetic sensor generates an electrical signal that is indicative of a position of the movable object.

Abstract: A porous discriminating layer is formed on a ceramic support having at least one porous wall by (a) establishing a flow of a gas stream containing highly porous particles through the support to deposit a layer of the highly porous particles of a ceramic or ceramic precursor onto wall(s) of the support and (b) calcining said deposited layer to form the discriminating layer. This method is an inexpensive and effective route to forming a discriminating layer onto the porous wall.

Abstract: A system for controlling movement of a cursor on a display device, the system comprising: a substrate having a position-coding pattern disposed on or in a surface thereof; a sensing device comprising: an image sensor for optically imaging the position-coding pattern; and a processor configured for: generating absolute motion data by determining a plurality of absolute positions of the sensing device relative to the surface using the imaged position-coding pattern; generating orientation data indicative of an orientation of the sensing device relative to the substrate; and using the orientation data to translate the absolute motion data into relative motion data, said relative motion data being indicative of relative motion of the sensing device from the perspective of a user; and communication means for communicating the relative motion data to a computer system; and the computer system configured for: receiving said relative motion data from the sensing device; interpreting said relative motion data as curso

Abstract: In one embodiment, a composition (10) to be mixed with a molten metal to make a metal matrix composite, the composition characterized by: a ceramic reinforcing filler (12), the ceramic reinforcing filler not being wettable by molten aluminum and/or not being chemically stable in molten aluminum, the ceramic reinforcing filler being coated with a ceramic material, the ceramic material being wettable by and chemically stable in molten aluminum. In a related embodiment, a composition (20) to make a porous preform to be infiltrated by molten metal to make a metal matrix composite, the composition characterized by: a ceramic reinforcing filler (23), the ceramic reinforcing filler not being wettable by molten aluminum, the ceramic reinforcing filler being coated with a ceramic material (22) and optionally with a metal (21) such as nickel, the ceramic material being wettable by molten aluminum.

Abstract: A sensor used to sense the position of an attached movable object. The sensor can be mounted to a pneumatic actuator. The sensor includes a housing that has a pair of cavities or pockets separated by a wall. A magnet carrier is positioned within one of the cavities and a magnet is coupled to the magnet carrier. The magnet carrier is coupled to the moveable object. A magnetic sensor is positioned in the other of the cavities. The magnetic sensor generates an electrical signal that is indicative of a position of the movable object.

Abstract: A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment with a cardiac glycoside in a disease having an etiology associated with excessive cell proliferation. The kit and assay are used to determine the ratio of isoforms of the ? subunit of Na, K-ATPase obtained from the diseased cell or tissue. The kit can be used to predict the therapeutic responsiveness of cancer or tumor in a subject to treatment with a cardiac glycoside. The kit and assay can be incorporated in a method of treating a disease or disorder having an etiology associated with excessive cell proliferation with a composition comprising a cardiac glycoside.

Abstract: A system for providing information to a user via a printed substrate. The system includes the printed substrate, an optically imaging pen device and a display device. The optically imaging pen device is configured for reading coded data from the substrate; generating interaction data using the coded data; and sending the interaction data to a computer system. Receipt of the interaction data by the computer system causes the computer system to: identify and retrieve a page description corresponding to the printed substrate; generate a query expression including one or more search terms; form a request using the query expression; and send the request to the display device.

Abstract: A method of interacting with a substrate and communicating with a computer system using an optical sensing device operable in a plurality of modes including a cursor control mode and a hyperlinking mode. The method includes the steps of: actuating a nib switch of the optical sensing device when a nib force exceeds a predetermined threshold; optically imaging coded data printed on the substrate; generating cursor control data when the optical sensing device is in said cursor control mode; generating interaction data using the imaged coded data when the optical sensing device is in the hyperlinking mode; and communicating the cursor control data or the interaction data to a computer system. The cursor control data initiates a cursor control response in the computer system while the interaction data initiates a hyperlinking response in the computer system.

Abstract: The invention relates to a computer system for modeling an oilfield having a subterranean formation and an underground reservoir therein. The computer system includes a repository storing a geomechanical model for representing at least a portion of the subterranean formation and the reservoir, the geomechanical model comprising a stress equation and a fluid flow equation, a processor and memory storing instructions when executed by the processor comprising functionalities for combining the stress equation and the fluid flow equation into a matrix equation, and modeling the oilfield by solving the stress equation and the fluid flow equation simultaneously.

Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachidonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.

Abstract: An aluminum-boron-carbon (ABC) ceramic-metal composite bonded to a metal or metal-ceramic composite other than ABC composite is made by forming a porous body comprised of particulates being comprised of a boron-carbon compound that has a particulate layer of titanium diboride powder on the surface of the porous body. The porous body is infiltrated with aluminum or alloy thereof resulting in the simultaneous infiltration of the TiB2 layer, where the layer has an aluminum metal content that is at least about 10 percentage points greater by volume than the (ABC) composite. The ABC composite is then fused to a metal or metal-ceramic body through the infiltrated layer of titanium diboride, wherein the metal-ceramic body is a composite other than an aluminum-boron-carbon composite.

Abstract: A method of treating neurological condition in a subject by administration of an extract, or fraction or sub-fraction thereof, of Nerium species or Thevetia species is provided, wherein the extract, or fraction or sub-fraction thereof, excludes oleandrin and neriifolin. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of the extract, or a fraction or sub-fraction thereof, to a subject. The extract can be present in a pharmaceutical composition.