Abstract: A prosthetic device includes a main body, a first anchor, and a second anchor. The main body has an atrial end and a ventricular end. The main body tapers from the atrial end to the ventricular end. The first and second anchors are coupled to the main body and are movable toward and away from the main body.

Abstract: Systems and processes for application integration with a digital assistant are provided. In accordance with one example, a method includes, at an electronic device having one or more processors and memory, receiving a natural-language user input; identifying, with the one or more processors, an intent object of a set of intent objects and a parameter associated with the intent, where the intent object and the parameter are derived from the natural-language user input. The method further includes identifying a software application associated with the intent object of the set of intent objects; and providing the intent object and the parameter to the software application.

Abstract: In some examples, a device may include a backlight unit configured to illuminate a display. In some examples, a light source may direct light into an active photonic circuit. The active photonic circuit may include optical switches controllable to distribute the light to illuminate display zones. An active photonic circuit may include an arrangement of optical switches configured to allow particular zones to be raster scanned, for example, using light distribution and outcoupling further using a passive photonic circuit. The illumination intensity for each zone may be controlled using the optical switches and/or with variation of the light source intensity. In some examples, the illumination intensity for each zone can be varied based on the displayed content, allowing improved contrast ratios. In some examples, all zones may be illuminated simultaneously with a zonal illumination intensity based on displayed content. Other devices, methods, systems, and computer-readable media are also disclosed.

Abstract: A tire comprising a continuous channel defined by spaced apart sidewalls coupled at a first end to a bridging member and at a second end to a contact member that is coupled to a disc contact portion, said tire being formed by rotational molding of a polyurethane and configured for mounting on a wheel rim.

Abstract: A load wheel for a vehicle is provided having a cylindrical hub with an axis, a first sidewall, a second sidewall, an outer surface, a central core extending coaxially within the hub, and a plurality of passageways extending in an axial direction between the first and second sidewall. A solid, non-pneumatic tire is bonded to the outer surface of the hub, and a set of bearing is mounted in the central core of the hub. The hub is characterized by a “heat factor” equal to the (hub mass×hub specific heat)/surface area exposed. The heat factor for a hub comprising passageways is compared to the heat factor for a solid hub to derive a heat factor ratio, which is used to select the exposed surface area of the hub and maintain the operating temperature of the wheel below the failure temperature.

Abstract: Various embodiments of a feedthrough header assembly and a device including such assembly are disclosed. The assembly includes a header having an inner surface and an outer surface; a dielectric substrate having a first major surface and a second major surface, where the second major surface of the dielectric substrate is disposed adjacent to the inner surface of the header; and a patterned conductive layer disposed on the first major surface of the dielectric substrate, where the patterned conductive layer includes a first conductive portion and a second conductive portion electrically isolated from the first conductive portion. The assembly further includes a feedthrough pin electrically connected to the second conductive portion of the patterned conductive layer and disposed within a via that extends through the dielectric substrate and the header. The feedthrough pin extends beyond the outer surface of the header.

Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.

Abstract: A system for control of motors for industrial applications including a motor control center and motor control unit. The motor control center having at least one printed circuit board, and a motor control unit having at least one pin. At least one pin includes a barrel, a plunger, and a spring. The motor control unit is selectively insertable into the motor control center, whereas the at least one pin transitions from the first position to the second position upon insertion and the at least one pin connects to the at least one printed circuit board forming an electrical connection between the motor control center and motor control unit.

Abstract: An approach for heat management in wearable devices is provided. One or more vibration enhanced convection heat transfer surfaces may be incorporated to exterior surfaces of a wearable device. A controller may take into account ambient temperature, available power expected power consumption by the vibration enhanced convection heat transfer surface(s), and/or expected heat reduction, and activate the vibration enhanced convection heat transfer surface(s) to expel heat from the wearable device. Operational parameters of the vibration enhanced convection heat transfer surface(s) such as a frequency and/or an amplitude of vibration may also be determined and set based on the internal and external factors including a shape, a location, and/or a size of the vibration enhanced convection heat transfer surface(s).

Abstract: Disclosed herein are methods, compositions, kits, and agents useful for inducing ? cell maturation, and isolated populations of SC-? cells for use in various applications, such as cell therapy.

Abstract: A high voltage-driven system includes a high voltage optical transformer and a high voltage driven device, where the high voltage optical transformer is located in close proximity to the high voltage driven device. A high voltage connection between the high voltage optical transformer and the high voltage driven device may be shorter than a low voltage connection between the high voltage optical transformer and a low voltage power source used to control the transformer.

Abstract: According to examples, an energy harvesting component for an optical device having an illumination source emitting unused light is described. The apparatus may include a light source to generate and transmit display light comprising at least one beam of light and an illumination source component to receive the at least one beam of light and to diffract the at least one beam of light in a first direction and an opposing direction. The apparatus may further include and an energy harvesting component to receive and absorb the at least one beam of light diffracted in an opposing direction and to convert the at least one beam of light diffracted in an opposing direction into electrical energy.

Abstract: A high-voltage optical transformer may include (1) an array of light-emitting devices that are connected in parallel with one another and are electrically coupled to an electrical input, (2) a transfer medium, and (3) an array of photovoltaic cells that (A) are optically coupled to the array of light-emitting devices via the transfer medium, (B) are connected in series with one another, and (C) produce an electrical output whose voltage is higher than the electrical input. Various other apparatuses, systems, and methods are also disclosed.

Abstract: In one aspect disclosed herein are small molecule inhibitors of CD38 and their use in treating, inhibiting, decreasing, reducing, ameliorating and/or preventing graft versus host disease, ischemia reperfusion injury, graft rejection, inflammatory injury to a graft or a graft recipient. Additionally, disclosed herein are methods of inhibiting CD38 pathway and activity comprising contacting a cell expressing CD38 or administering to a subject in need of CD38 inhibition, any of the small molecule CD38 inhibitors disclosed herein.

Abstract: A thermoplastic interposer formed of ordered polymer sheets that may be configured to act as an interconnect and as a thermal energy spreader. In examples, the thermoplastic interposer may include one or more extensions or wings to further dissipate heat. In examples, laser direct structuring (LDS) may be used to form or more through silicon vias (TSVs) or through-chip vias. In examples, the ordered polymer sheets may be extruded via a roll-to-roll process, stacked, and processed to form a laminate interposer structure that makes up the interposer. In examples, the thermoplastic interposer may be used in multi-layer structures interconnecting two or more board assemblies such as printed circuit boards (PCB)s.

Abstract: A liquid lens with flexible transparent active layers on both sides of a fluid is transformed along two distinct deformation axes. The flexible transparent active layers include piezoelectric materials that actuate the lens in response to applied voltage(s). The piezoelectric properties and actuation mechanism of the transparent layers are arranged to deform the lens cylindrically along different axes resulting in a net spherical deformation or a combination of spherical and cylindrical deformation with substantially less distortion than spherically deforming layers. The piezoelectric active layers may be polymer or ceramic with isotropic or anisotropic mechanical stiffness. Alternatively, a pair of transparent, internal layers are positioned between the front and rear surfaces. The active layers, front and/or rear, are dual layers affixed together with an adhesive or single layers.

Abstract: A mechanically and piezoelectrically anisotropic polymer article is formed from a crystallizable fluoropolymer and a nucleating agent. The polymer article may be a thin film or a fiber, for example. A crystalline phase may constitute at least approximately 50% of the polymer article. In certain examples, a fluoropolymer may include vinylidene fluoride, trifluoroethylene, chlorotrifluoroethylene, hexafluoropropylene, and vinyl fluoride. The polymer article may include up to approximately 10 wt. % of the nucleating agent. Such a polymer article is optically transparent, has an elastic modulus of at least approximately 3 GPa, and an electromechanical coupling factor (k31) of at least approximately 0.15.

Abstract: Angular sensors that may be used in eye-tracking systems are disclosed. An eye-tracking system may include a plurality of light sources to emit illumination light and a plurality of angular light sensors to receive returning light that is the illumination light reflecting from an eyebox region. The angular light sensors may output angular signals representing an angle of incidence of the returning light.

Abstract: A method of forming a high voltage optical transformer includes forming a via through a transparent carrier wafer, forming a conductive layer within the via, bonding a solid state lighting (SSL) package to a first side of the carrier wafer, and bonding a photovoltaic (PV) wafer to a second side of the carrier wafer opposite to the first side. The photovoltaic wafer may include an active area and a conductive area located outside of the active area that is in electrical contact with the conductive layer. The method further includes forming both an SSL contact with the solid state lighting package and a PV contact with the conductive layer on the same side of the carrier wafer.

Abstract: A device includes a light source to emit light and a light detector to receive the light emitted by the light source. The device may include a high voltage optical transformer and may be configured such that the light detector is laterally spaced away from the light source. In some architectures, the light source and the light detector may be arranged in a common plane. A photonic integrated circuit may be used to couple light emitted from the light source to the light detector.