Patents by Inventor Robert A. Reenan

Robert A. Reenan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN-DERIVED MUTANTS OF THE dSOD1 GENE IN DROSOPHILA AND METHODS OF MAKING AND USING
    Publication number: 20160000054
    Abstract: Genetic models of amyotrophic lateral sclerosis (ALS) are described, which can be used to identify novel treatments of ALS and therapeutic targets. Methods for making and using human-derived mutants of the Drosophila dSOD1 gene that model familial ALS are provided. Methods of identifying therapeutic ALS gene targets also are provided.
    Type: Application
    Filed: June 17, 2015
    Publication date: January 7, 2016
    Applicant: Brown University Research Foundation
    Inventor: Robert Reenan
  • Polynucleotides encoding cellular transporters and methods of use thereof
    Patent number: 7118873
    Abstract: This disclosure encompasses the Indy gene, polypeptides encoded by the Indy gene and fragments thereof. This disclosure also encompasses homologs of the Indy gene both from Drosophila and other organisms. In addition, this disclosure encompasses the use of Indy polynucleotides, INDY proteins and polypeptides, antibodies to the INDY protein, antagonists that inhibit Indy activity or expression, and agonists that increase Indy activity or expression, in the diagnosis or treatment of body weight disorders or longevity in humans and animals.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: October 10, 2006
    Assignee: The University of Connecticut
    Inventors: Robert A. Reenan, Blanka Rogina, Stephen L. Helfand
  • Polynucleotides encoding cellular transporters and methods of use thereof
    Publication number: 20030104399
    Abstract: This disclosure encompasses the Indy gene, polypeptides encoded by the Indy gene and fragments thereof. This disclosure also encompasses homologs of the Indy gene both from Drosophila and other organisms. In addition, this disclosure encompasses the use of Indy polynucleotides, INDY proteins and polypeptides, antibodies to the INDY protein, antagonists that inhibit Indy activity or expression, and agonists that increase Indy activity or expression, in the diagnosis or treatment of body weight disorders or longevity in humans and animals.
    Type: Application
    Filed: December 12, 2001
    Publication date: June 5, 2003
    Inventors: Robert A. Reenan, Blanka Rogina, Stephen L. Helfand
  • Transporter protein
    Publication number: 20030082647
    Abstract: This disclosure provides in part a method of evaluating a compound. The method includes: contacting a carboxylate transporter polypeptide with a test compound; evaluating an interaction between the test compound and the carboxylate transporter polypeptide; contacting a cell or organism that produces the carboxylate transporter polypeptide with the test compound; and evaluating the effect of the test compound on the rate of aging of the cell or organism.
    Type: Application
    Filed: June 12, 2002
    Publication date: May 1, 2003
    Inventors: Robert A. Reenan, Blanka Rogina, Stephen L. Helfand