Abstract: Methods and devices comprised of a collapsible insert member and shaping member for treating obstructive sleep apnea are described. The insert member is placed in the tongue or other tissue forming the airway of the patient and has a lumen to accommodate the shaping member. The shaping member is inserted into the insert member by the patient just prior to sleep and removed upon waking. A variety of shaping members are available to treat patients on an individual basis, i.e., to match their particular anatomic condition that is causing their apnea or snoring. The shaping member can be made from nitinol, stainless steel, or any other known biocompatible implant material capable of providing a change in the tissue response to stress.

Abstract: A linear actuator comprises a motor for producing a bi-directional rotational output. A casing is connected to the motor at a proximal end, the casing having an inner cavity defining a joint surface. A threaded shaft is within the inner cavity of the casing and actuated by the motor for rotation. A sliding tube assembly has a sliding tube in sliding arrangement with the inner cavity of the casing for moving in translation in an axial direction relative to the casing. A pair of traveling nuts is connected to the sliding tube assembly for moving with the sliding tube in the axial direction, the traveling nuts being operatively engaged to the threaded shaft for converting a rotational motion of the threaded shaft into a translation of the sliding tube, the traveling nuts being on opposite sides of a member of the sliding tube assembly connecting the traveling nuts to the sliding tube.

Abstract: A device is disclosed for the securement of dermal tissues. The device provides approximation and eversion of the tissue as well as the placement of a fixation element that bridges a wound. The fixation element may be produced in several fixed or dynamic configurations that may or may not alter the ability to engage tissue in response to stresses placed upon the fixation member post-deployment. The delivery device inserts the fastener percutaneously through the epidermis into the sub-dermal position without entering the wound margins with any part of the approximation portion of the delivery device.

Abstract: This invention provides methods, devices and kits for treating coronary artery disease, particularly “soft” or vulnerable plaque. The invention is based on the local delivery of crosslinking means to crosslink the collagen covering the plaque and other proteins that may be present at the site to stabilize the plaque and prevent leakage of thrombogenic material into the lumen of the coronary artery. In certain embodiments, catheters are employed to achieve local delivery of a crosslinking agent or ultraviolet light.

Abstract: A diaphragm for a loudspeaker drive unit or for a microphone includes a rigid dome-shaped member having a thickness that varies from a first thicker thickness at a first location at the periphery of the dome-shaped member to a second thinner thickness at a second location, which is nearer to the centre of the dome-shaped member. There is a step-wise change in thickness at a location between the first location and the second location. Having greater thickness at the periphery of the dome-shaped member may improve stiffness of the diaphragm and may allow for an increased break-up frequency. Having thinner material elsewhere in the dome-shaped member may allow the mass of the diaphragm to be kept low and may result in better acoustic sensitivity.

Abstract: A linear actuator comprising a motor having an output shaft. A casing of the motor has an inner cavity defining a joint surface. A threaded shaft is within the inner cavity of the casing, and a bearing within the inner cavity. A coupling assembly couples the output shaft to the threaded shaft, and has a first coupling component receiving the rotational output from the motor, and a second coupling component coupled to the first coupling component for transmission of the rotational output to the threaded shaft. A substantial portion of a coupling is in an axial section of the linear actuator delimited by a proximal and distal surface of the bearing. A sliding tube is within the inner cavity and translates relative to the casing. A traveling nut is connected to the sliding tube for moving therewith for converting a rotational motion of the threaded shaft into a translation of the sliding tube.

Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.

Abstract: A diaphragm for a loudspeaker drive unit or for a microphone includes a rigid dome-shaped member having a thickness that varies from a first thicker thickness at a first location at the periphery of the dome-shaped member to a second thinner thickness at a second location, which is nearer to the center of the dome-shaped member. There is a step-wise change in thickness at a location between the first location and the second location. Having greater thickness at the periphery of the dome-shaped member may improve stiffness of the diaphragm and may allow for an increased break-up frequency. Having thinner material elsewhere in the dome-shaped member may allow the mass of the diaphragm to be kept low and may result in better acoustic sensitivity.

Abstract: A system and method are disclosed for the securement of tissue and in particular for placement of a tongue base suspension fiber for the treatment of obstructive sleep apnea. The system incorporates disposable connectors with releasable needles to facilitate the placement of fibers with minimal increase in suture site dilation or trauma.

Abstract: Polymeric fibers, and apparatuses for and methods of processing such fibers to be useful as sutures, where at least one end of a fiber includes a termination feature. The termination feature is formed through the application of energy to a coiled region of the fiber.

Abstract: A loudspeaker chassis assembly (2) comprises a loudspeaker chassis (4) and one or more mass damping elements (6), which dampen vibration of the chassis (4). The mass damping elements (6) may be directly attached to the chassis (4) and may be tuned to dampen one or more particular vibrational modes of the chassis (4).

Abstract: An implant for treating obstructive sleep apnea includes a flexible chamber, a fluid reservoir in fluid communication with the flexible chamber, and a fluid transfer assembly in communication with the fluid reservoir and the flexible chamber for transferring fluid therebetween for selectively modifying the rigidity of the flexible chamber. The flexible chamber is implantable within the soft tissue of an oropharyngeal airway of a patient, such as within the tongue, the soft palate, or the pharyngeal wall. The fluid reservoir and the fluid transfer assembly are implantable within the inframandibular region of the patient. The fluid transfer assembly is selectively engageable by the patient for transferring fluid between the two chambers for modifying the rigidity, flexibility, and/or shape of the flexible chamber with minimal or no change to the volume of the implant.

Abstract: Polymeric fibers, and apparatuses for and methods of processing such fibers to be useful as sutures, where at least one end of a fiber includes a termination feature. The termination feature is formed through the application of energy to a coiled region of the fiber.

Abstract: Polymeric fibers, and apparatuses for and methods of processing such fibers to be useful as sutures, where at least one end of a fiber includes a termination feature. The termination feature is formed through the application of energy to a coiled region of the fiber.

Abstract: A linear actuator comprises a motor having an output. An end block is connected to a casing and to the motor and has a counterbore at a distal end with a bearing seated and retained in the counterbore. A coupling assembly couples the output shaft of the motor to a threaded shaft for transmission of the rotational output to the threaded shaft. A sliding tube is in sliding arrangement with the inner cavity of the casing for moving in translation relative to the casing.

Abstract: A linear actuator comprising a motor having an output shaft. A casing of the motor has an inner cavity defining a joint surface. A threaded shaft is within the inner cavity of the casing, and a bearing within the inner cavity. A coupling assembly couples the output shaft to the threaded shaft, and has a first coupling component receiving the rotational output from the motor, and a second coupling component coupled to the first coupling component for transmission of the rotational output to the threaded shaft. A substantial portion of a coupling is in an axial section of the linear actuator delimited by a proximal and distal surface of the bearing. A sliding tube is within the inner cavity and translates relative to the casing. A traveling nut is connected to the sliding tube for moving therewith for converting a rotational motion of the threaded shaft into a translation of the sliding tube.

Abstract: A linear actuator comprises a motor having an output shaft. A casing of the motor has an inner cavity with a counterbore seat surface. A threaded shaft is within the inner cavity. A bearing is received in the counterbore seat surface. A coupling assembly has a first coupling component receiving the rotational output from the motor, and a second coupling component coupled to the first coupling component for transmission of the rotational output to the threaded shaft. A sliding tube is sliding arrangement with the casing for moving in translation relative to the casing. A traveling nut is in the sliding tube for moving therewith for converting a rotational motion of the threaded shaft into a translation of the sliding tube. An integral driven assembly unit comprising the bearing, the threaded shaft, the traveling nut and the sliding tube interconnected to one another so as to be removable by pulling out the integral driven assembly as a whole from the inner cavity of the casing via the proximal end.

Abstract: Obstructive Sleep Apnea (OSA) may be caused by a collapse of the pharyngeal wall as a result of increasing negative airway pressure. This invention is directed to systems and methods to resist collapse of the pharyngeal wall by minimally invasive upper pharyngeal airway surgery.

Abstract: A tissue supporting device is provided and method of use. The device includes an anchor element having a plate-like element and first and second side walls extending upwardly therefrom. The plate-like element is defined by front and rear edges, and first and second side edges, with the rear edge being longer than the front edge. The first and second side walls are aligned substantially along at least a portion of the first and second side edges of the plate-like element such that a distance between the first and second side walls at a front side is less than a distance between the first and second side walls at a rear side. The device also includes a soft tissue supporting element adapted for engaging and supporting soft tissue. The soft tissue supporting element is coupled to the plate-like element and extends outwardly from the anchor element.

Abstract: A pharyngeal retractor device and implantation methods are provided for use in the treatment of obstructive sleep apnea. The device includes a retracting element and a tissue engaging element that promotes tissue ingrowth around or onto the retracting element. The device is implanted in tissue space beneath the pharyngeal wall to alter the shape of the wall. The device may be implanted through the oral cavity alone or by using a trocar or a hand-held delivery system to deliver the device through the pharyngeal wall. Alternatively, the device may be implanted using an open, direct visualization approach from the side of a patient's neck.