Patents by Inventor Robert A. Scherrer
Robert A. Scherrer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8173113Abstract: A bioadhesive composition that adheres suitably to a mucosal surface and is capable of delivering drugs in sustained fashion, and a patch comprising the bioadhesive composition. Methods of using and processes for preparing the bioadhesive composition are also described.Type: GrantFiled: May 14, 1997Date of Patent: May 8, 2012Assignee: 3M Innovative Properties CompanyInventors: Matthew T. Scholz, Robert A. Scherrer, Nelda M. Marecki, Yen-Lane Chen, Joan K. Barkhaus
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Publication number: 20080063714Abstract: The invention comprises compositions and methods useful for encapsulation and controlled release of guest molecules, such as drugs. Compositions of the present invention comprise a matrix comprising molecules that are non-covalently crosslinked by multi-valent cations, wherein the molecules that are non-covalently crosslinked are non-polymeric, have more than one carboxy functional group, and have at least partial aromatic or heteroaromatic character The compositions are characterized in that a guest molecule may be encapsulated within the matrix and subsequently released.Type: ApplicationFiled: July 29, 2004Publication date: March 13, 2008Inventors: Hassan Sahouani, Robert A. Scherrer, Kim M. Vogel, Dennis E. Vogel, Stephen W. Stein, Brian J. Gabrio, Stephanie F. Bernatchez, Richard H. Ferber, Wei Zou
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Patent number: 7186402Abstract: The invention comprises a medicinal aerosol composition comprising a propellant, an excipient comprising an acid or amine end-group and at least one and no more than two amide and/or ester functional groups, and a drug. The invention also comprises particulate medicinal compositions comprising particles with a mean mass aerodynamic diameter of less than about 10 microns that incorporate an excipient containing an acid or amine end-group and at least one and no more than two amide and/or ester functional groups.Type: GrantFiled: December 20, 2002Date of Patent: March 6, 2007Assignee: 3M Innovative Properties CompanyInventors: Daniel C. Duan, Robert A. Scherrer, James S. Stefely
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Publication number: 20030147814Abstract: The invention comprises hydrofluorocarbon medicinal aerosol solutions comprising an ion pair complex comprising a drug and an excipient. The invention also relates to methods for delivering a highly respirable dose to a mammal with a medicinal aerosol comprising an ion pair complex.Type: ApplicationFiled: December 20, 2002Publication date: August 7, 2003Applicant: 3M Innovative Properties CompanyInventors: Robert A. Scherrer, James S. Stefely, Stephen W. Stein
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Publication number: 20030138381Abstract: The invention comprises a medicinal aerosol composition comprising a propellant, an excipient comprising an acid or amine end-group and at least one and no more than two amide and/or ester functional groups, and a drug. The invention also comprises particulate medicinal compositions comprising particles with a mean mass aerodynamic diameter of less than about 10 microns that incorporate an excipient containing an acid or amine end-group and at least one and no more than two amide and/or ester functional groups.Type: ApplicationFiled: December 20, 2002Publication date: July 24, 2003Applicant: 3M Innovative Properties CompanyInventors: Daniel C. Duan, Robert A. Scherrer, James S. Stefely
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Patent number: 5750136Abstract: A bioadhesive composition that adheres suitably to a mucosal surface and is capable of delivering drugs in sustained fashion, and a patch comprising the bioadhesive composition. Methods of using and processes for preparing the bioadhesive composition are also described.Type: GrantFiled: May 31, 1995Date of Patent: May 12, 1998Assignee: Riker Laboratories, Inc.Inventors: Matthew T. Scholz, Robert A. Scherrer, Nelda M. Marecki, Yen-Lane Chen, Joan K. Barkhaus
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Patent number: 5750134Abstract: A bioadhesive composition that adheres suitably to a mucosal surface and is capable of delivering drugs in sustained fashion, and a patch comprising the bioadhesive composition. Methods of using and processes for preparing the bioadhesive composition are also described.Type: GrantFiled: May 31, 1995Date of Patent: May 12, 1998Assignee: Riker Laboratories, Inc.Inventors: Matthew T. Scholz, Robert A. Scherrer, Nelda M. Marecki, Yen-Lane Chen, Joan K. Barkhaus
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Patent number: 5527824Abstract: Substituted Di-T-Butylphenols useful for inhibiting the synthesis of leukotrienes are disclosed.Type: GrantFiled: May 5, 1995Date of Patent: June 18, 1996Assignee: Riker Laboratories, Inc.Inventor: Robert A. Scherrer
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Patent number: 5498745Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents. Pharmaceutical compositions containing and pharmacological methods of using such compounds are also disclosed, as are synthetic intermediates for preparing such compounds. Certain of the synthetic intermediates also exhibit useful antiallergic activity.Type: GrantFiled: May 5, 1995Date of Patent: March 12, 1996Assignee: Riker Laboratories, Inc.Inventor: Robert A. Scherrer
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Patent number: 5495043Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents. Pharmaceutical compositions containing and pharmacological methods of using such compounds are also disclosed, as are synthetic intermediates for preparing such compounds. Certain of the synthetic intermediates also exhibit useful antiallergic activity.Type: GrantFiled: May 5, 1995Date of Patent: February 27, 1996Assignee: Riker Laboratories, Inc.Inventor: Robert A. Scherrer
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Patent number: 5416113Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents. Pharmaceutical compositions containing and pharmacological methods of using such compounds are also disclosed, as are synthetic intermediates for preparing such compounds. Certain of the synthetic intermediates also exhibit useful antiallergic activity.Type: GrantFiled: June 22, 1994Date of Patent: May 16, 1995Assignee: Riker Laboratories, Inc.Inventor: Robert A. Scherrer
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Patent number: 5347036Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents. Pharmaceutical compositions containing and pharmacological methods of using such compounds are also disclosed, as are synthetic intermediates for preparing such compounds. Certain of the synthetic intermediates also exhibit useful antiallergic activity.Type: GrantFiled: May 26, 1993Date of Patent: September 13, 1994Assignee: Riker Laboratories, Inc.Inventor: Robert A. Scherrer
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Patent number: 5244997Abstract: Amino-ester catalysts for curing water-curable isocyanate-functional materials. Also disclosed are catalysis methods and curable compositions involving amino-ester catalysts, and casting articles and methods of orthopedic casting.Type: GrantFiled: September 4, 1992Date of Patent: September 14, 1993Assignee: Minnesota Mining and Manufacturing CompanyInventors: Matthew T. Scholz, Robert A. Scherrer
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Patent number: 5237070Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents. Pharmaceutical compositions containing and pharmacological methods of using such compounds are also disclosed, as are synthetic intermediates for preparing such compounds. Certain of the synthetic intermediates also exhibit useful antiallergic activity.Type: GrantFiled: May 16, 1991Date of Patent: August 17, 1993Assignee: Riker Laboratories, Inc.Inventor: Robert A. Scherrer
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Patent number: 5225513Abstract: Catalyzes methods and curable compositions involving amino-ester catalysts and isocyanate-functional materials. Also disclosed are casting articles and methods of orthopedic casting.Type: GrantFiled: August 8, 1991Date of Patent: July 6, 1993Assignee: Minnesota Mining and Manufacturing CompanyInventors: Matthew T. Scholz, Robert A. Scherrer
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Patent number: 5103037Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted in the 4 position by a carbamyl or acylamino group, which carbamyl or acylamino group is substituted by a group which includes an acidic substituent are useful as inhibitors of leukotriene biosynthesis and as antiallergic agents. Pharmacological methods for using such compounds and synthetic intermediates for preparing such compounds are also disclosed.Type: GrantFiled: May 13, 1991Date of Patent: April 7, 1992Assignee: Riker Laboratories, Inc.Inventors: Robert A. Scherrer, Mark A. Rustad
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Patent number: 5049572Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted in the 4 position by a carbamyl or acylamino group, which carbamyl or acylamino group is substituted by a group which includes an acidic substituent are useful as inhibitors of leukotriene biosynthesis and as antiallergic agents. Pharmacological methods for using such compounds and synthetic intermediates for preparing such compounds are also disclosed.Type: GrantFiled: October 1, 1990Date of Patent: September 17, 1991Assignee: Riker Laboratories, Inc.Inventors: Robert A. Scherrer, Mark A. Rustad
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Patent number: 4851513Abstract: Chemically-modified collagen is prepared by reacting native collagen with a di or tri-carboxylic acid halide, di or tri-sulfonyl halide, di or tri-anhydride, or di or tri-reative active ester coupling agent. The reaction is done in a controlled manner so that the degree of cross-linking is limited. Any remaining lysine epsilon amino groups present in the coupled collagen product may be converted to carboxyamido or sulfonamido groups by acid halide, anhydride, sulfonyl halide or active ester amine-modifying agents. The resultant product when dissolved in a physiological buffer provides a viscoelastic solution having therapeutic application in a variety of surgical procedures, particularly in ophthalmic surgery. This viscoelastic solution "melts," i.e., exhibits a dramatic loss of viscosity, when subjected to temperatures of between 32.degree. and 48.degree. C.Type: GrantFiled: October 5, 1987Date of Patent: July 25, 1989Assignee: Minnesota Mining and Manufacturing CompanyInventors: Dale P. Devore, Robert A. Scherrer, Matthew T. Scholz
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Patent number: 4716178Abstract: Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a group which includes carboxyl, tetrazolyl or N-methyltetrazolyl are useful as inhibitors of leukotriene synthesis and as antiallergic agents. Pharmaceutical compositions containing such compounds and pharmacological methods for use of such compounds are also disclosed.Type: GrantFiled: August 27, 1986Date of Patent: December 29, 1987Assignee: Riker Laboratories, Inc.Inventors: Robert A. Scherrer, Mark A. Rustad
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Patent number: RE33574Abstract: Novel compounds which are 2,6-di-tertiary-butylphenols substituted in the 4 position by an acylaminophenyl group, which acylaminophenyl group is substituted by a moiety which includes a carboxyl group, are useful as inhibitors of leukotriene biosynthesis and as antiallergic agents.Type: GrantFiled: January 24, 1990Date of Patent: April 23, 1991Assignee: Riker Laboratories, Inc.Inventors: Alan R. Kirk, Robert A. Scherrer