Abstract: A unique piping arrangement of a water pump system is designed to prevent backflow of non-potable liquid into a potable water source thereby complying with plumbing codes to provide a safe cross connection. These codes are required when a water ejector uses pressurized potable water as an energy source. When the water ejector valve is open due to a high sump level and when the potable water pressure drops below atmospheric, the non-potable liquid can be siphoned into the potable water source thereby causing contamination, a significant unsafe health hazard to consumers. The present invention complies with plumbing codes by creating the required vertical air gap from the potable water source down to the non-potable liquid in the discharge piping as well as the inlet piping, the sources of contamination. In the piping arrangement are vents and drains to create the required air gap and transparent piping to provide required inspection and verification of proper operation.

Abstract: A decorative bar, configured to be mounted on a surface (wall or floor) of a room or building, comprises (a) an elongate rod formed of natural stone and having a substantially constant cross-sectional shape from a first end to an opposite, second end and a longitudinal groove extending along one side, and (b) an elongate metal armature or brace having a portion thereof inserted in and substantially filling the longitudinal groove in the stone rod. The metal brace has a flange or bracket at each end configured to be attached to the surface (wall or floor) of a building to affix and retain the stone rod in a mounted relationship to this surface with its longitudinal groove on a side which is not readily visible to a casual observer.

Abstract: The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. Finally, there is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets.

Abstract: A scalp care composition directed to a scalp care composition comprising from about 0.05% to about 5% of an anti-dandruff active, from about 0.1% to about 25% of one or more organic solvents, from about 1% to about 99% of a volatile carrier wherein the anti-dandruff active is soluble in the scalp care composition.

Abstract: A method of improving the health of hair emerging from a scalp comprising a reduction of oxidative stress in the scalp by application of a composition resulting in reduction in oxidative stress in pre-emergent hair as demonstrated by reduced oxidative stress in emergent hair.

Abstract: Elongated conductors are provided. Aspects of the elongated conductors include: an elongated structure having a proximal region and a distal region, where the elongated conductor includes two or more insulated conducting members that are in fixed relative position along at least a portion of the elongated structure and extend from the proximal region to the distal region. A pattern of insulation openings among the insulated conducting members is present at one or both of the proximal and distal regions. Aspects of the invention further include methods of making the elongated conductors, as well as devices that include the elongated conductors.

Abstract: The present disclosure describes the role for miR-322(424)/503 in the differentiation of cardiac precursor cells. Thus, the use of these molecules in the programming of resident stem/progenitor cells into cardiomyocytes, both in vitro and in vivo. Such methods find particular use in the treatment of patients post-myocardial infarction to prevent or limit scarring and to promote myocardial repair.

Abstract: The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.

Abstract: The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. Finally, there is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets.

Abstract: A scalp care composition comprising from 1% to 99% of a volatile carrier; from 0.05% to 10% of a polymeric rheology modifier and mixtures thereof; from 0.03% to 1% of particulate scalp benefit agent wherein the composition is shear thinning and has (1) a zero shear viscosity value measured at 0.01 Pa of greater than about 1,500 Pa s; (2) a moderate stress viscosity value measured at 1 Pa viscosity of greater than about 1,000 Pa s; and (3) a high shear rate viscosity value measured at 100 l/s of less than about 0.5 Pa s.

Abstract: A package including an intimate cleansing product, a deodorant composition, and in some cases a razor is disclosed herein. The deodorant composition includes an anti-irritation agent. The intimate cleansing product, deodorant composition and razor are co-packaged together. Or, the intimate cleansing product and the deodorant composition are co-packaged together.

Abstract: Systems and methods are provided for automatically configuring an email client during a migration process. An client-side assistant can be deployed to an end-user's computer via a migration platform. After being deployed to a particular client computer, the client-side assistant can be configured to obtain user information to identify the end-user associated with the client computer. After identifying the end-user, destination system information regarding the end-user can be pushed to client computer for inclusion in new configuration information for the email client. Before generating the new configuration information, user credential for logging into the source system can be obtained. The client-side assistant can be configured to cause the destination system to confirm this credential. After generating the new configuration information, the client-side assistant can instruct the client-side assistant to use the new configuration information to at a specific time and date.

Abstract: The present invention relates to a composition comprising an effective amount of a particulate zinc material, an effective amount of a surfactant including a surfactant with an anionic functional group wherein the particulate zinc material has a relative zinc lability of greater than about 15 % and wherein the composition comprises less than 5.5 micromoles of a zinc binding material per gram of the particulate zinc material/per m2/gram surface area of the particulate zinc material.

Abstract: The present invention relates to a composition comprising an effective amount of a particulate zinc material, an effective amount of a detersive surfactant including a surfactant with an anionic functional group, an effective amount of a pyrithione or a polyvalent metal salt of a pyrithione, a dispersed gel network phase comprising: i) at least about 0.05% of one or more fatty amphiphiles, by weight of said shampoo composition; ii) at least about 0.01% of one or more secondary surfactants, by weight of said shampoo composition; and iii) water; and at least about 20% of an aqueous carrier, by weight of said shampoo composition.

Abstract: Systems, methods, and apparatuses can provide staged migration from one or more user accounts from a source system to a destination system using an application local to the source systems. The automated staged data migration can provide coordinated staged data migration of large amounts of data in a single automated process. The system can provide automated and remotely controlled staged migrations of data that may perform source system type detection and work with multiple types of systems.

Abstract: Systems, methods, and apparatuses can present optimized data migration. Embodiments can provide improved data migration processes using a data migration assistant that executes on a source system to facilitate the migration of documents and data to a destination system. The migration assistant can communicate with a migration controller server to authenticate and identify the migration assistant and migration project that the migration assistant is to be used for. The migration controller server can use the identifier to determine commands corresponding to the migration project to send to the migration assistant to collect data and make changes to the source system.

Abstract: Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g.