Patents by Inventor Robert A. Setterquist

Robert A. Setterquist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8426126
    Abstract: The invention relates to methods of separating polynucleotides, such as DNA, RNA and PNA, from solutions containing polynucleotides by reversibly binding the polynucleotides to a solid surface, such as a magnetic microparticle.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: April 23, 2013
    Assignee: Applied Biosystems, LLC
    Inventors: Gary J. Latham, Xingwang Fang, Richard C. Conrad, Jon A. Kemppainen, Robert A. Setterquist, Brittan L. Pasloske
  • Patent number: 8361754
    Abstract: The present invention relates to a gene that encodes a hyperactive reverse transcriptase having DNA polymerase activity and substantially reduced RNase H activity, vectors containing the gene and host cells transformed with the invention. The present invention also includes a method of producing the hyperactive reverse transcriptase, producing cDNA from mRNA using the reverse transcriptase of the invention, kits and assay templates made using the hyperactive reverse transcriptase.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: January 29, 2013
    Assignee: Applied Biosystems, LLC
    Inventors: Liangjing Chen, Robert A. Setterquist, Gary Latham
  • Publication number: 20100203597
    Abstract: The present invention relates to a gene that encodes a hyperactive reverse transcriptase having DNA polymerase activity and substantially reduced RNase H activity, vectors containing the gene and host cells transformed with the invention. The present invention also includes a method of producing the hyperactive reverse transcriptase, producing cDNA from mRNA using the reverse transcriptase of the invention, kits and assay templates made using the hyperactive reverse transcriptase.
    Type: Application
    Filed: September 28, 2009
    Publication date: August 12, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Liangjing Chen, Robert A. Setterquist, Gary Latham
  • Patent number: 7595179
    Abstract: The present invention relates to a gene that encodes a hyperactive reverse transcriptase having DNA polymerase activity and substantially reduced RNase H activity, vectors containing the gene and host cells transformed with the invention. The present invention also includes a method of producing the hyperactive reverse transcriptase, producing cDNA from mRNA using the reverse transcriptase of the invention, kits and assay templates made using the hyperactive reverse transcriptase.
    Type: Grant
    Filed: April 19, 2004
    Date of Patent: September 29, 2009
    Assignee: Applied Biosystems, LLC
    Inventors: Liangjing Chen, Robert A. Setterquist, Gary J. Latham
  • Patent number: 6994963
    Abstract: This invention pertains to a method for generating a pool of nucleic acid fragments useful for in vitro recombination and the creation of novel DNA sequences that encode desirable proteins or enzymes. The invention provides a defined mixture of nucleic acids and methods for use in the synthesis, mutagenesis, and recombination of nucleic acids. Nucleic acids may be synthesized by creating a nucleic acid extension ladder, annealing the extension ladder to template nucleic acids, and further extending the ladder of nucleic acids. The invention also relates to methods for performing repeated cycles of synthesis for the purpose of mutagenesis or recombination, methods for producing mutant peptides and proteins from the mutagenized or recombined nucleic acids, and methods for selecting a peptide, polypeptide or protein having altered biological activities.
    Type: Grant
    Filed: July 10, 2000
    Date of Patent: February 7, 2006
    Assignee: Ambion, Inc.
    Inventors: George L. Murphy, Robert A. Setterquist, Andrew D. Ellington