Patents by Inventor Robert A. Snow
Robert A. Snow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170159564Abstract: A system for managing thermal transfer in at least one of an aircraft or a gas turbine engine includes a first engine system utilizing an oil for heat transfer. The oil of the first system has a temperature limit of at least about 500° F. The system additionally includes a fuel system having a deoxygenation unit for deoxygenating fuel in the fuel system, as well as a fuel-oil heat exchanger located downstream of the deoxygenation unit. The fuel-oil heat exchanger is in thermal communication with the oil in the first engine system and the fuel in the fuel system for transferring heat from the oil in the first engine system to the fuel in the fuel system.Type: ApplicationFiled: December 8, 2015Publication date: June 8, 2017Inventors: Brandon Wayne Miller, Duane Howard Anstead, Mohammed El Hacin Sennoun, Ning Fang, Kyle Robert Snow
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Publication number: 20170159569Abstract: A system for managing thermal transfer in at least one of an aircraft or a gas turbine engine includes a first engine system utilizing an oil for heat transfer. The oil of the first system has a temperature limit of at least about 500° F. The system additionally includes a fuel system having a deoxygenation unit for deoxygenating fuel in the fuel system, as well as a fuel-oil heat exchanger located downstream of the deoxygenation unit. The fuel-oil heat exchanger is in thermal communication with the oil in the first engine system and the fuel in the fuel system for transferring heat from the oil in the first engine system to the fuel in the fuel system.Type: ApplicationFiled: February 11, 2016Publication date: June 8, 2017Inventors: Brandon Wayne Miller, Duane Howard Anstead, Mohammed El Hacin Sennoun, Ning Fang, Kyle Robert Snow
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Publication number: 20170130606Abstract: A self-contained lubrication fluid circulation system for use with a gas turbine engine defining a core air flowpath includes a sump configured to collect lubrication fluid and a heat source coupled in fluid communication with the sump and configured to transfer heat to the lubrication fluid. The system also includes a heat sink positioned within the sump and coupled in fluid communication with the heat source. A lubrication fluid conduit of the system is configured to channel the lubrication fluid between the heat source and the heat sink, wherein the lubrication fluid conduit is positioned entirely within the sump.Type: ApplicationFiled: November 10, 2015Publication date: May 11, 2017Inventors: Daniel Alan Niergarth, Brandon Wayne Miller, Kyle Robert Snow, Christopher James Kroger
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Publication number: 20170114831Abstract: A bearing apparatus includes: a bearing including a first race rotatable relative to a second race, wherein the first race includes one or more drain passages extending therethrough; and a squeeze film damper connected to the first race, the squeeze film damper including first and second squeeze film spaces separated by an oil drain path which communicates with the one or more drain passages of the first race.Type: ApplicationFiled: October 21, 2015Publication date: April 27, 2017Inventors: Kyle Robert Snow, Philip J. Ogston, Christopher Michael Grady
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Publication number: 20170067397Abstract: In one aspect, the present disclosure is directed to a bearing compartment sealing system including a bearing for supporting a shaft. A housing encloses the bearing and defines a compartment for holding lubricant therein. At least two seals are located between the shaft and the housing. The at least two seals, the housing, and the shaft collectively enclose the compartment. Only one of the at least two seals is a hydrodynamic seal.Type: ApplicationFiled: September 4, 2015Publication date: March 9, 2017Inventors: Ning FANG, Scott WOLFER, Adam Mitchell RECORD, Jonathan K. REMER, Daryl Scott SCHNEIDER, Jacob Patrick MILLER, Kyle Robert SNOW
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Publication number: 20160376924Abstract: A gas turbine engine is provided defining a radial direction. The gas turbine engine generally includes a compressor section and a turbine section, the compressor section and turbine section together defining a core air flowpath. The gas turbine engine also includes a sump positioned inward of the core air flowpath along the radial direction. An air pump is positioned inward of the core air flowpath along the radial direction for providing a flow of air from the sump to lower an internal pressure of the sump and reduce a likelihood of lubrication leaking from the sump.Type: ApplicationFiled: June 24, 2015Publication date: December 29, 2016Inventors: Brandon Wayne MILLER, Matthew Timothy FRANER, Kyle Robert SNOW
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Publication number: 20160115438Abstract: Provided herein are isolation processes and the associated hardware to allow fluid streams to be isolated from a sterilized system (e.g., a sterile process vessel) that contains a sterile process. The isolation processes described herein allow for continuous removal of fluid streams (e.g., waste streams, liquid containing recombinant therapeutic proteins) from a sterilized system (e.g., a biological manufacturing system), which provides for less manual manipulation of the sterilized system and a decreased risk of contaminating the sterilized system.Type: ApplicationFiled: October 20, 2015Publication date: April 28, 2016Inventor: Robert Snow
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Patent number: 9066701Abstract: A surgical access system comprising a tissue retraction assembly equipped with two or more electrodes for use in monitoring the status of nearby neural structures, including the localized depth of neural structures relative to one or more components of the tissue retraction assembly. Additional neurological testing may be performed to monitor the health and status of the neural structures during the portions of the surgical procedure in which the tissue retraction assembly is used to maintain the operative corridor.Type: GrantFiled: February 6, 2013Date of Patent: June 30, 2015Assignee: NuVasive, Inc.Inventors: Eric Finley, James Gharib, Richard A. O'Brien, Robert Snow
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Patent number: 8703202Abstract: Disclosed is a pharmaceutically acceptable oral dosage form comprising fenofibrate, phospholipid, a buffer salt, a water-soluble bulking agent selected from maltodextrin, mannitol, and combinations thereof, a cellulosic additive, beads or crystals of a pharmaceutically acceptable water-soluble excipient support material, a polyvinylpyrrolidone or crospovidone, croscarmellose sodium, granular mannitol, sodium dodecyl sulfate, silicon dioxide, and a stearate, wherein the fenofibrate is in the form of microparticles, and wherein at least a portion of the phospholipid is coated on the surfaces of the fenofibrate microparticles, the phospholipid coated microparticles are embedded in a matrix comprising the water-soluble bulking agent, phospholipid that is not coated on the microparticles, the buffer salt and the cellulosic additive, and the matrix is coated on up to 100% of the surfaces of the beads or crystals of the excipient support material.Type: GrantFiled: July 24, 2006Date of Patent: April 22, 2014Assignee: Jagotec AGInventors: Michael Vachon, Mishra K. Awadhesh, Robert A. Snow, Pol-Henri Guivarc'h
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Patent number: 8586094Abstract: Disclosed is a pharmaceutically acceptable oral dosage form comprising fenofibrate, phospholipid, a buffer salt, a water-soluble bulking agent selected from maltodextrin, mannitol, and combinations thereof, a cellulosic additive, beads or crystals of a pharmaceutically acceptable water-soluble excipient support material, a polyvinylpyrrolidone or crospovidone, croscarmellose sodium, granular mannitol, sodium dodecyl sulfate, silicon dioxide, and a stearate, wherein the fenofibrate is in the form of microparticles, and wherein at least a portion of the phospholipid is coated on the surfaces of the fenofibrate microparticles, the phospholipid coated microparticles are embedded in a matrix comprising the water-soluble bulking agent, phospholipid that is not coated on the microparticles, the buffer salt and the cellulosic additive, and the matrix is coated on up to 100% of the surfaces of the beads or crystals of the excipient support material.Type: GrantFiled: May 2, 2003Date of Patent: November 19, 2013Assignee: Jagotec AGInventors: Michael Vachon, Mishra K. Awadesh, Robert A. Snow, Pol-Henri Guivarc'H
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Publication number: 20120064160Abstract: This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the form of microparticles of solid fenofibrate that are stabilized by phospholipid as a surface active substance, wherein a therapeutically effective amount of the composition provides the statin and a quantity of fenofibrate to a fasted human patient that is greater than 80% of the quantity of fenofibrate provided by the same amount of the composition when administered to the same patient who has been fed a high fat meal.Type: ApplicationFiled: November 14, 2011Publication date: March 15, 2012Applicant: Jagotec AGInventors: Pol-Henri Guivarc'h, Indu Parikh, Robert A. Snow
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Patent number: 7572913Abstract: Substituted piperidine compounds represented by the structure I are provided, wherein each of R1a, R1b, R1c, R1d, R1e, R1f, R1g, R1h, R2, R2A, R3, R4, A, X, a, x and n is as defined in the specification. Substituted piperidine compounds of structure I may permeate or penetrate across a nerve cell membrane into the interior of a nerve cell, may inhibit intracellular Rho kinase enzyme found in nerve cells in mammals, and may find utility in repair of damaged nerves in the central and peripheral nervous system of such mammals. These compounds may induce the regeneration or growth of neurites in mammalian nerve cells and may thereby induce regeneration of damaged or diseased nerve tissue. These compounds also find additional utility as antagonists of the enzyme Rho kinase in treatment of disease states in which Rho kinase is implicated.Type: GrantFiled: February 24, 2005Date of Patent: August 11, 2009Assignee: Bioaxone Therapeutique Inc.Inventors: Lisa McKerracher, Eryk Thouin, William Lubell, Robert Snow, Karine Gingras
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Publication number: 20060257494Abstract: Disclosed is a pharmaceutically acceptable oral dosage form comprising fenofibrate, phospholipid, a buffer salt, a water-soluble bulking agent selected from maltodextrin, mannitol, and combinations thereof, a cellulosic additive, beads or crystals of a pharmaceutically acceptable water-soluble excipient support material, a polyvinylpyrrolidone or crospovidone, croscarmellose sodium, granular mannitol, sodium dodecyl sulfate, silicon dioxide, and a stearate, wherein the fenofibrate is in the form of microparticles, and wherein at least a portion of the phospholipid is coated on the surfaces of the fenofibrate microparticles, the phospholipid coated microparticles are embedded in a matrix comprising the water-soluble bulking agent, phospholipid that is not coated on the microparticles, the buffer salt and the cellulosic additive, and the matrix is coated on up to 100% of the surfaces of the beads or crystals of the excipient support material.Type: ApplicationFiled: July 24, 2006Publication date: November 16, 2006Inventors: Michael Vachon, Awadhesh Mishra, Robert Snow, Pol-Henri Guivarc'h
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Publication number: 20060210622Abstract: This invention disclosure relates to compositions for the delivery of stable surface modified sub-micron and micron sized particles of water-insoluble biologically active substances from a non-aqueous medium that self-disperses on exposure to an aqueous environment.Type: ApplicationFiled: November 14, 2005Publication date: September 21, 2006Inventors: Gary Pace, Awadhesh Mishra, Robert Snow
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Publication number: 20060199991Abstract: The invention provides the use of a radiation source which is a low energy X-ray emitter, e.g. with an energy of emission of the principal photon in the range of 20 to 100 keV, preferably 20 to 40 keV and with a half life of 10 to 100 days, preferably 15 to 70 days, for the treatment of restenosis. Suitable radioisotopes include palladium-103, dysprosium-159, samarium-145, cadmium-109, ytterbium-169 and preferably iodine-125. High activity radioactive bodies and sources comprising such radioisotopes, and methods for the manufacture of such sources, are also disclosed.Type: ApplicationFiled: February 28, 2006Publication date: September 7, 2006Inventors: Dewi Lewis, Lucinda Dollimore, Nigel Powell, Gregory McIntire, Evan Gustow, Robert Snow
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Patent number: 7011619Abstract: The invention provides the use of a radiation source which is a low energy X-ray emitter, e.g. with an energy of emission of the principal photon in the range of 20 to 100 keV, preferably 20 to 40 keV and with a half life of 10 to 100 days, preferably 15 to 70 days, for the treatment of restenosis. Suitable radioisotopes include palladium-103, dysprosium-159, samarium-145, cadmium-109, ytterbium-169 and preferably iodine-125. High activity radioactive bodies and sources comprising such radioisotopes, and methods for the manufacture of such sources, are also disclosed.Type: GrantFiled: August 13, 1999Date of Patent: March 14, 2006Assignee: GE Healthcare LimitedInventors: Dewi M. Lewis, Lucinda A. Dollimore, Nigel Powell, Gregory L. McIntire, Evan Gustow, Robert A. Snow
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Publication number: 20060027037Abstract: A transmission includes an input shaft, an output shaft, a first plurality of gears, a second plurality of gears, and a series of engagement elements operable between an engaged position and a disengaged position. A controller is further provided to selectively toggle the series of engagement elements between the engaged position and the disengaged position to selectively couple one of the first plurality of gears or one of the second plurality of gears to the input shaft and the output shaft. The series of engagement elements sequentially couples the first plurality of gears to the input shaft and the output shaft during operation of the transmission and selectively couples one of the first plurality of gears or the second plurality of gears to the input shaft and the output shaft during a downshift operation of the transmission.Type: ApplicationFiled: August 6, 2004Publication date: February 9, 2006Inventors: Hussein Dourra, Robert Snow
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Publication number: 20050272751Abstract: Substituted piperidine compounds represented by the structure I are provided, wherein each of R1a, R1b, R1c, R1d, R1e, R1f, R1g, R1h, R2, R2A, R3, R4, A, X, a, x and n is as defined in the specification. Substituted piperidine compounds of structure I may permeate or penetrate across a nerve cell membrane into the interior of a nerve cell, may inhibit intracellular Rho kinase enzyme found in nerve cells in mammals, and may find utility in repair of damaged nerves in the central and peripheral nervous system of such mammals. These compounds may induce the regeneration or growth of neurites in mammalian nerve cells and may thereby induce regeneration of damaged or diseased nerve tissue. These compounds also find additional utility as antagonists of the enzyme Rho kinase in treatment of disease states in which Rho kinase is implicated.Type: ApplicationFiled: February 24, 2005Publication date: December 8, 2005Applicant: Bioaxone Therapeutique Inc.Inventors: Lisa McKerracher, Eryk Thouin, William Lubell, Robert Snow, Karine Gingras
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Publication number: 20040097779Abstract: Radioactive sources, preferably radioactive seeds, for use in brachytherapy comprising a radioisotope within a sealed biocompatible container, wherein at least one part of a surface of the container is roughened, shaped or otherwise treated so that it is no longer smooth. The surface treatment may enhance the ultrasound visibility of the source and/or reduce the tendency of the source to migrate once implanted in a patient's body. Preferred radioisotopes are palladium-103 and iodine-125.Type: ApplicationFiled: November 6, 2003Publication date: May 20, 2004Inventors: Gregory Mclntire, Robert Snow, Edward Bacon, Morten Eriksen, Auden Tornes, Geraldine Cooney, Virginia Ann Gates, Joel Cornacoff, Christopher Black
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Publication number: 20040091535Abstract: Disclosed is a pharmaceutically acceptable oral dosage form comprising fenofibrate, phospholipid, a buffer salt, a water-soluble bulking agent selected from maltodextrin, mannitol, and combinations thereof, a cellulosic additive, beads or crystals of a pharmaceutically acceptable water-soluble excipient support material, a polyvinylpyrrolidone or crospovidone, croscarmellose sodium, granular mannitol, sodium dodecyl sulfate, silicon dioxide, and a stearate, wherein the fenofibrate is in the form of microparticles, and wherein at least a portion of the phospholipid is coated on the surfaces of the fenofibrate microparticles, the phospholipid coated microparticles are embedded in a matrix comprising the water-soluble bulking agent, phospholipid that is not coated on the microparticles, the buffer salt and the cellulosic additive, and the matrix is coated on up to 100% of the surfaces of the beads or crystals of the excipient support material.Type: ApplicationFiled: May 2, 2003Publication date: May 13, 2004Applicant: SKYEPHARMA CANADA INC.Inventors: Michael Vachon, Awadhesh K. Mishra, Robert A. Snow, Pol-Henri Guivarc'H