Patents by Inventor Robert A. Weersink
Robert A. Weersink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10607738Abstract: Various embodiments are described herein for a system and a method for treatment planning for providing ablative therapy to a patient. The treatment planning may involve segmenting images of the patient to define areas to receive treatment, defining trial parameters, simulating treatment of ablative therapy to the patient according to the trial parameters; analyzing a thermal dose distribution resulting from the simulated treatment to determine treatment effectiveness; determining when the treatment effectiveness meets a treatment effectiveness criteria; and providing an indication of the trial parameters when the treatment effectiveness meets the treatment effectiveness criteria.Type: GrantFiled: May 13, 2016Date of Patent: March 31, 2020Assignees: University Health Network, Sunnybrook Research InstituteInventors: Sean Davidson, Michael D. Sherar, Kieran Murphy, Claire McCann, Robert Weersink
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Publication number: 20170319719Abstract: There is provided herein a nanovesicle having a bilayer comprising a saturated first phospholipid and no more than about 15 molar % of a second phospholipid covalently conjugated to a J-aggregate forming dye.Type: ApplicationFiled: July 27, 2017Publication date: November 9, 2017Applicant: UNIVERSITY HEALTH NETWORKInventors: Gang Zheng, Elizabeth Huynh, Kenneth Ng, Mojdeh Shakiba, Robert Weersink, Brian Wilson
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Publication number: 20160335413Abstract: Various embodiments are described herein for a system and a method for treatment planning for providing ablative therapy to a patient. The treatment planning may involve segmenting images of the patient to define areas to receive treatment, defining trial parameters, simulating treatment of ablative therapy to the patient according to the trial parameters; analyzing a thermal dose distribution resulting from the simulated treatment to determine treatment effectiveness; determining when the treatment effectiveness meets a treatment effectiveness criteria; and providing an indication of the trial parameters when the treatment effectiveness meets the treatment effectiveness criteria.Type: ApplicationFiled: May 13, 2016Publication date: November 17, 2016Applicant: University Health NetworkInventors: Sean Davidson, Michael D. Sherar, Kieran Murphy, Claire McCann, Robert Weersink
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Patent number: 9330490Abstract: Methods and systems for visualization of 3D parametric data in a 2D image. The set of 3D parametric data includes a plurality of voxels in 3D space each associated with at least one parametric value, and the set of 2D image data includes information about a known camera position and a known camera orientation at which the 2D image was obtained. A graphical representation is generated of the parametric values of the voxels corresponding to a viewing surface in 3D space. A virtual 2D view of the viewing surface is determined. The 2D image is displayed registered with the graphical representation of the parametric values of the voxels corresponding to the virtual 2D view.Type: GrantFiled: April 26, 2012Date of Patent: May 3, 2016Assignee: UNIVERSITY HEALTH NETWORKInventors: Robert Weersink, David A. Jaffray, Jimmy Qiu, Andrew Hope, John Cho, Michael B. Sharpe
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Publication number: 20150359912Abstract: There is provided herein a nanovesicle having a bilayer comprising a saturated first phospholipid and no more than about 15 molar % of a second phospholipid covalently conjugated to a J-aggregate forming dye.Type: ApplicationFiled: January 28, 2014Publication date: December 17, 2015Applicant: UNIVERSITY HEALTH NETWORKInventors: Gang Zheng, Elizabeth Huynh, Kenneth Ng, Mojdeh Shakiba, Robert Weersink, Brian Wilson
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Patent number: 9138597Abstract: A method, computer program product and processor for quantitatively registering a 2D endoscopic ROI in a 3D volumetric imaging dataset. An endoscopic dataset and a volumetric imaging are registered to a common coordinate system. A 2D endoscopic ROI is generated within the endoscopic imaging dataset. A 3D surface ROI is generated within the volumetric imaging dataset corresponding to the 2D endoscopic ROI, based on a projection of the 2D endoscopic ROI to the registered common coordinate system.Type: GrantFiled: May 13, 2010Date of Patent: September 22, 2015Assignee: University Health NetworkInventors: Robert Weersink, Andrew Hope, Jeff Siewerdsen, David Jaffray, Aidin Kashigar, Michael Daly, Jonathon Eubank, John Cho
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Publication number: 20130113802Abstract: Methods and systems for visualization of 3D parametric data in a 2D image. The set of 3D parametric data includes a plurality of voxels in 3D space each associated with at least one parametric value, and the set of 2D image data includes information about a known camera position and a known camera orientation at which the 2D image was obtained. A graphical representation is generated of the parametric values of the voxels corresponding to a viewing surface in 3D space. A virtual 2D view of the viewing surface is determined. The 2D image is displayed registered with the graphical representation of the parametric values of the voxels corresponding to the virtual 2D view.Type: ApplicationFiled: April 26, 2012Publication date: May 9, 2013Applicant: UNIVERSITY HEALTH NETWORKInventors: Robert WEERSINK, David A. JAFFRAY, Jimmy QIU, Andrew HOPE, John CHO, Michael B. SHARPE
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Publication number: 20120155731Abstract: A method, computer program product and processor for quantitatively registering a 2D endoscopic ROI in a 3D volumetric imaging dataset. An endoscopic dataset and a volumetric imaging are registered to a common coordinate system. A 2D endoscopic ROI is generated within the endoscopic imaging dataset. A 3D surface ROI is generated within the volumetric imaging dataset corresponding to the 2D endoscopic ROI, based on a projection of the 2D endoscopic ROI to the registered common coordinate system.Type: ApplicationFiled: May 13, 2010Publication date: June 21, 2012Applicant: University Health NetworkInventors: Robert Weersink, Andrew Hope, Jeff Siewerdsen, David Jaffray, Aidin Kashigar, Michael Daly, Jonathon Eubank, John Cho
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Publication number: 20110106222Abstract: A treatment device (2) includes a mobile cart (4) on which is mounted a housing (6) and an upright 8 to which is pivotally mounted, at hinge region (9), a second upright (11). An arm (12) is pivotally mounted at hinge region (10) to upright (11). Arm (12) supports a head piece (14) via a hinged joint (16). The housing (6) encloses a power supply, parts of a closed circuit cooling system arranged to cool the head piece (14) in use and electronic components. A user-operable control panel (18) for the device is mounted at a convenient height on the upright (8).Type: ApplicationFiled: April 24, 2009Publication date: May 5, 2011Inventors: Brian Wilson, Brock Miller, Robert Weersink, Kai Zhang, George Newtchev
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Publication number: 20080255461Abstract: Multiple site information of light intensity is obtained by application of a multiple-fibre probe in a real-time optical monitoring system. The multiple-fibre probe includes a plurality of optical fibres distributed along the length of the probe. Each optical fibre may be is switchable between the mode for transmitting optical signal into the malignant tissue and the mode for collecting the optical signal from the same tissue. Thus the numbers of the probes can be minimized for collecting multiple site light information and the irritation to the tissue is reduced. A method of using such a probe to determine coagulated boundary in thermal or other treatment is also described.Type: ApplicationFiled: March 26, 2008Publication date: October 16, 2008Inventors: Robert Weersink, Lee Chin, John Trachtenberg, Alex Vitkin, William Whelan, Brian C. Wilson
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Patent number: 6413267Abstract: A method is provided for treating a patient having a disorder, wherein the method includes irradiating a tissue surface of the patient with at least one laser beam, automatically monitoring the tissue, and automatically controlling the at least one laser beam to adjust and/or terminate the treatment in a therapeutically effective manner. The method noninvasively determines in real-time the irradiance and/or radiant exposure of a target tissue at a predetermined depth below the tissue surface by detecting the radial dependence of light remitted from the tissue surface. Preferably, the method employs a near-infrared light laser beam and a visible laser light beam in combination. An apparatus for performing the method is also provided.Type: GrantFiled: August 9, 1999Date of Patent: July 2, 2002Assignee: Theralase, Inc.Inventors: Roger J. Dumoulin-White, Lothar Lilge, Robert A. Weersink
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Patent number: 6344051Abstract: A method is provided for treating a patient having a disorder, wherein the method includes irradiating a tissue surface of the patient with at least one laser beam, automatically monitoring the tissue, and automatically controlling the at least one laser beam to adjust and/or terminate the treatment in a therapeutically effective manner. The method noninvasively determines in real-time the irradiance and/or radiant exposure of a target tissue at a predetermined depth below the tissue surface by detecting the radial dependence of light remitted from the tissue surface. Preferably, the method employs a near-infrared light laser beam and a visible laser light beam in combination. An apparatus for performing the method is also provided.Type: GrantFiled: August 9, 1999Date of Patent: February 5, 2002Assignee: Theralase, Inc.Inventors: Roger J. Dumoulin-White, Lothar Lilge, Robert A. Weersink
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Patent number: 6219566Abstract: The present invention provides a method for measurement of concentration of fluorophores in turbid media. The method uses a fluorescence plus reflectance technique to measure quantitatively the in vivo concentration of a fluorescent drug independent of the tissue optical properties. The method involves using the reflectance measurement as a means of correcting for tissue scattering and absorption in the fluorescence measurement. Light directed to the tissue by means of an optical fiber to excite the fluorophores. Fluorescence from the fluorophores is measured by another fiber at a distance (D1) from the source in the turbid medium, while the excitation light is simultaneously collected at a distance (D2) from the source. The ratio fluorescence/reflectance will be approximately constant for a fixed concentration of the fluorophore and a judicious choice of D1 and D2, regardless of the optical properties of the tissue.Type: GrantFiled: July 13, 1999Date of Patent: April 17, 2001Assignee: Photonics Research OntarioInventors: Robert A. Weersink, Michael S. Patterson