Patents by Inventor Robert Aarhus

Robert Aarhus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Caged nucleotides
    Patent number: 5872243
    Abstract: The present invention describes a family of photolabile caged nucleotides, including cyclic nucleotides. The compounds of the present invention are caged analogs and derivatives of NAD.sup.+, NADH, NADP, NADPH, NAADP and cADPR. The photolysis of the present compounds allows the release of the free nucleotide in vivo or in vitro with precise spatial and temporal control. The compounds are useful for the photolytic generation of free nucleotides in aqueous samples, for example, in the study of calcium mobilization in cells and cell homogenates.
    Type: Grant
    Filed: June 30, 1995
    Date of Patent: February 16, 1999
    Assignees: Molecular Probes, Inc., The Regents of the University of Minnesota
    Inventors: Kyle R. Gee, Hon Cheung Lee, Robert Aarhus, Richard P. Haugland, Timothy F. Walseth, Richard M. Graeff