Abstract: Provided herein are phosphodiesterase 4 (PDE4) degraders, e.g., a compound of Formula (I) or (IA), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a PDE4-mediated disease, disorder, or condition.

Abstract: A hot water delivery system includes a water heater, a mixing valve that is coupled to the output of the water heater, and a plurality of loads that are coupled to the output of the mixing valve. A load set point temperature of each load that is representative of a maximum temperature of the hot water that is to be delivered to the respective load is set by a user. Responsive to detecting the occurrence of an event associated with a load of the plurality of loads, a controller of the water heater controls the mixing valve to adjust the temperature of the hot water from the water heater to the load set point temperature associated with the load, provided the load set point temperature of the load is different from a water heater set point temperature at which the water heater maintains the hot water therein.

Abstract: A docking plate apparatus is provided for motorized floor conveyor vehicles, such as conveyance tuggers, that is particularly structured to provide tactile feedback at a determined stop position for improved docking and/or stopping placement. The docking plate apparatus has a structure and dimensions to ensure that the motorized floor conveyor vehicle is docked exactly in a determined stop position that is deemed most optimal for interaction with a delivery system. The docking plate apparatus can comprise body, which is a flat panel structure, and a docking aperture that is structured in a portion of the body. The docking aperture receiving at least one wheel of a motorized floor conveyor vehicle to dock the motorized vehicle in a determined stop position for interaction with the delivery system.

Abstract: A computer stores a reference image representing a physical background within a field of view of a camera of a client device. The computer receives, via the camera and during a video conference to which the client device is connected, camera-generated visual data for output to at least one remote device connected to the video conference. The computer identifies, based on facial recognition applied to the camera-generated visual data, foreground imagery representing at least one person and background imagery representing content of the camera-generated visual data other than the foreground imagery. The computer identifies a difference between the background imagery and the reference image. The computer generates a composite image by replacing, within the background imagery of the camera-generated visual data, an item represented within the background imagery and within the identified difference with a co-located part of the reference image.

Abstract: Systems and methods of lifting and installing a fuel tank on a vehicle are provided. In particular, a lifting apparatus may (1) receive fasteners and fuel tank bands prior to lifting, the fasteners secured/extended through fastener openings of the fuel tank bands; (2) lift, in a first lifting stage, the received fuel tank bands to a ground-facing surface of a fuel tank (the fuel tank may be resting on a pedestal or a similar support structure) such that the fuel tank bands cradle the fuel tank; and (3) lift, in a second lifting stage, the received fuel tank bands and the cradled fuel tank to the underside of a vehicle for installation.

Abstract: A vehicle wheel torque brace for inhibiting rotation of a vehicle wheel includes a brace body including a relatively thick stopper portion and a relatively thin wedge portion that is stepped down in thickness relative to the wedge portion. The wedge portion decreases in thickness from one side of the brace body to an opposite side of the brace body. A contact pad is carried by the wedge portion. The contact pad and wedge portion are shaped and sized to be wedged between a tire of the vehicle wheel and a strut assembly to inhibit rotation of the vehicle wheel.

Abstract: A vehicle wheel torque brace for inhibiting rotation of a vehicle wheel includes a brace body including a relatively thick stopper portion and a relatively thin wedge portion that is stepped down in thickness relative to the wedge portion. The wedge portion decreases in thickness from one side of the brace body to an opposite side of the brace body. A contact pad is carried by the wedge portion. The contact pad and wedge portion are shaped and sized to be wedged between a tire of the vehicle wheel and a strut assembly to inhibit rotation of the vehicle wheel.

Abstract: A medical device server can include a plurality of artificial intelligence medical devices, each trained for rendering a prediction related to a disease or medical condition. A healthcare provider can obtain patient data, including medical tests results, and send them to the medical device server as a request to obtain disease or health condition predictions. The patient data can be provided to an applicable artificial intelligence medical device whose input fields data type match and are present in the patient data embedded in a request received from the healthcare provider. The applicable artificial intelligence medical devices can render disease or health condition predictions, which are communicated to the healthcare provider in response to the request.

Abstract: A computer stores a reference image representing a physical background within a field of view of a camera of a client device. The computer receives, via the camera and during a video conference to which the client device is connected, camera-generated visual data for output to at least one remote device connected to the video conference. The computer identifies, based on facial recognition applied to the camera-generated visual data, foreground imagery representing at least one person and background imagery representing content of the camera-generated visual data other than the foreground imagery. The computer identifies a difference between the background imagery and the reference image. The computer generates a composite image by replacing, within the background imagery of the camera-generated visual data, an item represented within the background imagery and within the identified difference with a co-located part of the reference image.

Abstract: Methods are described for forming a mounting surface on a slider body. In one method, an adhesion layer can be deposited on a top surface of a slider body. A first photolithography cycle deposits a first metal layer having a first thickness of at least 8 ?m. A second photolithography cycle deposits a second metal layer having a second thickness of at least 8 ?m over the first metal layer. The first and second layer form a mounting support on the top surface. In another method, the top surface is etched to form a mounting support.

Abstract: A vehicle moving device for moving a vehicle from a first location to a second location includes a frame having a first end and a second end. A driving wheel is coupled to the first end of the frame and configured to contact a vehicle wheel at a first wheel location. A holding arm is coupled to the second end of the frame opposite the driving wheel and configured to contact the vehicle wheel at a second wheel location. The holding arm holds the vehicle wheel in contact with the driving wheel as the driving wheel rotates the vehicle wheel.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for securing data. One of the methods includes receiving one or more network data packets. The one or more network data packets include a token that identifies stored sensitive data. The one or more network data packets are desanitized, by: identifying and extracting, from the one or more network data packets, the token; requesting, from a distributed file system, the stored sensitive data, based upon the token; and receiving, in response to the request, the stored sensitive data as received stored sensitive data.

Abstract: Example guards for use with power tools and power tools including such guards. The guards include a collar structured to be removably coupled to a hand-guided electrical tool, a hood coupled to the collar, and a guard ring coupled to the collar via the hood. The guard ring extends entirely around the collar.

Abstract: Example guards for use with power tools and power tools including such guards. The guards include a collar structured to be removably coupled to a hand-guided electrical tool, a hood coupled to the collar, and a guard ring coupled to the collar via the hood. The guard ring extends entirely around the collar.

Abstract: A sanitation device is disclosed. The sanitation device includes a housing, one or more reflective panels, one or more bulb assemblies, and an access door. The one or more reflective panels and the access door define a chamber. The one or more bulb assemblies are positioned within the chamber.

Abstract: A slider includes a slider body with an air-bearing surface and a top surface opposing the air-bearing surface. A plurality of slider bond pads are disposed on or parallel to the top surface and proximate to or at a trailing edge of the slider. The plurality of slider bond pads have an exposed surface facing away from the top surface of the slider body. One or more mounting supports extend from the top surface to a distance of at least 12 ?m above the exposed surface of the plurality of slider bond pads.

Abstract: A rear suspension member (RSM) transfer assembly for transferring an RSM from a sub-assembly line to a main assembly line includes a first RSM lifter, an RSM buffer, and a second RSM lifter. The first RSM lifter is configured to travel laterally between the sub-assembly line and the main assembly line. The first RSM lifter includes a lifting body and a rotatable arm configured to retrieve the RSM from the sub-assembly line and transport the RSM to the main assembly line. The RSM buffer is configured to receive the RSM from the first RSM lifter and transport the RSM through a plurality of resting positions. The second RSM lifter is configured to receive the RSM from the RSM buffer and raise the RSM into position for installation on a vehicle.