Patents by Inventor Robert Abercrombie
Robert Abercrombie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11946269Abstract: The present disclosure provides for a modular design and build architecture, comprising: one or more integrated system module (ISMs) that are configured to be shipped and assembled on-site to construct an operational infrastructure for one or more application environments, wherein each of the ISMs comprises two or more different functional components that are integrated onto and/or supported by a common structural floor.Type: GrantFiled: November 4, 2022Date of Patent: April 2, 2024Assignee: Nautilus TRUE, LLCInventors: Gabe Andrews, Chase Abercrombie Ott, Robert C. Pfleging, Patrick J. Quirk
-
Patent number: 11938295Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.Type: GrantFiled: September 15, 2022Date of Patent: March 26, 2024Assignee: Biora Therapeutics, Inc.Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Ryan Elliott Jones, Kevin Howe, Pejman Rahimian, Nelson Quintana
-
Publication number: 20240042147Abstract: A dry powder inhaler includes an inhalation channel connected to a mouthpiece, a container for storing a powdered medicament, a de-agglomerator with a vortex chamber located at an end of the inhalation channel, a metering device including a shuttle having a dosing recess. The shuttle is movable between a filling position, in which the dosing recess is in alignment with an opening of the container, and an inhalation position, in which the dosing recess is in alignment with the vortex chamber. The opening of the container is elongated along a major axis and the dosing recess is elongated along a main axis and, when the shuttle is in the filling position, an edge of the opening of the container encloses the dosing recess.Type: ApplicationFiled: August 2, 2023Publication date: February 8, 2024Inventors: Marco DI CASTRI, Stuart Robert ABERCROMBIE, Donal Joseph TAYLOR
-
Patent number: 11707610Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.Type: GrantFiled: December 11, 2020Date of Patent: July 25, 2023Assignee: BIORA THERAPEUTICS, INC.Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Ryan Elliott Jones, Kevin Howe, Pejman Rahimian, Nelson Quintana
-
Publication number: 20230149315Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.Type: ApplicationFiled: December 11, 2020Publication date: May 18, 2023Inventors: Jeffrey A. SHIMIZU, Mitchell Lawrence JONES, Mark Sasha DRLIK, Iman NIKNIA, Nathan John MULLER, Tuyen NGUYEN, Christopher Loren WAHL, Edward MUDGE, Nicholas Mark SALT, Nia Eleri STEVENS, Stuart Robert ABERCROMBIE, Christopher Ian BUNCE, Ryan Elliott JONES, Kevin David HOWE, Pejman RAHIMIAN, Nelson QUINTANA
-
Publication number: 20230023414Abstract: This disclosure features methods and devices for treating diseases with orally-delivered biotherapeutics.Type: ApplicationFiled: November 19, 2019Publication date: January 26, 2023Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
-
Publication number: 20230017603Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.Type: ApplicationFiled: September 15, 2022Publication date: January 19, 2023Inventors: Jeffrey A. SHIMIZU, Mitchell Lawrence JONES, Mark Sasha DRLIK, Iman NIKNIA, Nathan John MULLER, Tuyen NGUYEN, Christopher Loren WAHL, Edward MUDGE, Nicholas Mark SALT, Nia Eleri STEVENS, Stuart Robert ABERCROMBIE, Christopher Ian BUNCE, Ryan Elliott JONES, Kevin HOWE, Pejman RAHIMIAN, Nelson QUINTANA
-
Patent number: 11439802Abstract: A method of treating a disease or condition in a subject in need thereof is disclosed. The method comprising: trans-epithelially administering a dispensable substance to the gastrointestinal (GI) tract of the subject by orally administering an ingestible device comprising the dispensable substance to the subject. The ingestible device is configured for trans-epithelial delivery of the dispensable substance to the GI tract of the subject and the dispensable substance comprises a pharmaceutical formulation comprising a therapeutically effective amount of a glucagon receptor agonist or a glucagon-like peptide-1 (GLP-1) receptor agonist. The ingestible device releases the dispensable substance as at least one jet to a desired location of the GI tract of the subject.Type: GrantFiled: May 13, 2021Date of Patent: September 13, 2022Assignee: Biora Therapeutics, Inc.Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
-
Publication number: 20220249814Abstract: This disclosure features methods and devices for treating diseases with orally-delivered biotherapeutics.Type: ApplicationFiled: November 19, 2019Publication date: August 11, 2022Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
-
Publication number: 20210283385Abstract: An ingestible device, includes a storage reservoir configured to store a dispensable substance and a pressurized chamber configured so that, when a restraining force is removed from the pressurized chamber, the dispensable substance exits the ingestible device via openings in the ingestible device.Type: ApplicationFiled: May 13, 2021Publication date: September 16, 2021Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
-
Patent number: 11007356Abstract: An ingestible device, includes a storage reservoir configured to store a dispensable substance and a pressurized chamber configured so that, when a restraining force is removed from the pressurized chamber, the dispensable substance exits the ingestible device via openings in the ingestible device.Type: GrantFiled: September 17, 2020Date of Patent: May 18, 2021Assignee: Progenity, Inc.Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
-
Publication number: 20210038872Abstract: An ingestible device, includes a storage reservoir configured to store a dispensable substance and a pressurized chamber configured so that, when a restraining force is removed from the pressurized chamber, the dispensable substance exits the ingestible device via openings in the ingestible device.Type: ApplicationFiled: September 17, 2020Publication date: February 11, 2021Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
-
Patent number: 10646265Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.Type: GrantFiled: December 15, 2014Date of Patent: May 12, 2020Assignee: Cryotherapeutics GmbHInventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
-
Publication number: 20200054558Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.Type: ApplicationFiled: March 20, 2019Publication date: February 20, 2020Applicant: PARION SCIENCES, INC.Inventors: Paul BOUCHER, Richard BOUCHER, Brian M. BUTTON, Michael R. JOHNSON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, William Robert THELIN, Stuart Robert ABERCROMBIE, Philip Jerome DRIVER, Mark Jeffrey EDHOUSE, Nicholas O. HEIJNE, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
-
Publication number: 20190275269Abstract: The present invention relates to a dry powder inhaler for administering a medicament via oral inhalation route to a subject. Particularly, the dry powder inhaler according to present invention is suitable for delivering accurate doses of a medicament in different ranges of inspiratory capacity of the subject.Type: ApplicationFiled: May 23, 2019Publication date: September 12, 2019Applicant: GLENMARK PHARMACEUTICALS LIMITEDInventors: Ulhas DHUPPAD, Rachel Rachel STRIEBIG, Scott Alexander LEWIS, Matthew David ALLEN, Lai Chiu TANG, Stuart Robert ABERCROMBIE, John William Sanford HALE, Thomas Stephen COLLINGS
-
Patent number: 10357622Abstract: The present invention relates to a dry powder inhaler for administering a medicament via oral inhalation route to a subject. Particularly, the dry powder inhaler according to present invention is suitable for delivering accurate doses of a medicament in different ranges of inspiratory capacity of the subject.Type: GrantFiled: December 23, 2014Date of Patent: July 23, 2019Assignee: GLENMARK PHARMACEUTICALS LIMITEDInventors: Ulhas Dhuppad, Rachel Victoria Striebig, Scott Alexander Lewis, Matthew David Allen, Lai Chiu Tang, Stuart Robert Abercrombie, John William Sanford Hale, Thomas Stephen Collings
-
Publication number: 20160361106Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.Type: ApplicationFiled: December 15, 2014Publication date: December 15, 2016Applicant: CRYOTHERAPEUTICS GMBHInventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
-
Publication number: 20150174346Abstract: The present invention relates to a dry powder inhaler for administering a medicament via oral inhalation route to a subject. Particularly, the dry powder inhaler according to present invention is suitable for delivering accurate doses of a medicament in different ranges of inspiratory capacity of the subject.Type: ApplicationFiled: December 23, 2014Publication date: June 25, 2015Inventors: Ulhas DHUPPAD, Rachel Victoria STRIEBIG, Scott Alexander LEWIS, Matthew David ALLEN, Lai Chiu TANG, Stuart Robert ABERCROMBIE, John William Sanford HALE, Thomas Stephen COLLINGS
-
Publication number: 20150150803Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.Type: ApplicationFiled: January 9, 2015Publication date: June 4, 2015Applicant: PARION SCIENCES, INC.Inventors: Paul BOUCHER, Richard BOUCHER, Brian M. BUTTON, Michael R. JOHNSON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, William Robert THELIN, Stuart Robert ABERCROMBIE, Philip Jerome DRIVER, Mark Jeffrey EDHOUSE, Nicholas O. HEIJNE, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
-
Patent number: 8945605Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.Type: GrantFiled: March 14, 2013Date of Patent: February 3, 2015Assignee: Parion Sciences, Inc.Inventors: Paul Boucher, Richard Boucher, Brian M. Button, Michael R. Johnson, James B. Fink, Anthony J. Hickey, Tomas Navratil, William Robert Thelin, Stuart Robert Abercrombie, Philip Jerome Driver, Mark Jeffrey Edhouse, Nicholas O. Heijne, Donal Joseph Taylor, Jonathan Hugh Wilkins