Patents by Inventor Robert Adamson

Robert Adamson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for purifying nucleic acids
    Patent number: 6011148
    Abstract: Methods are provided for producing highly purified compositions of nucleic acids by using tangential flow ultrafiltration. A scaleable process for producing pharmaceutical grade plasmid DNA, useful for gene therapy, is provided, which is efficient and avoids the use of toxic organic chemicals.
    Type: Grant
    Filed: August 1, 1996
    Date of Patent: January 4, 2000
    Assignee: Megabios Corporation
    Inventors: Lee B. Bussey, Robert Adamson, Alan Atchley
  • Medium and methods for culturing mammalian cho cells
    Patent number: 5830761
    Abstract: Cell culture media are provided containing high L-cystine concentration and low L-glutamic acid concentration. The media are useful for recombinant production of proteins using mammalian cell cultures.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 3, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Denis Drapeau, S. Robert Adamson, Yen-Tung Luan, Paul Thoday
  • Method for producing factor VIII:C-type proteins
    Patent number: 5250421
    Abstract: An improved method for producing Factor VIII:c-type proteins is disclosed which involves culturing mammalian cells which are capable of expressing the protein. In accordance with this invention the cells are cultured in a medium containing an effective amount of a substance comprising (a) von Willebrand Factor-type protein, (b) a phospholipid or phospholipid mixture, or a mixture of (a) and (b).
    Type: Grant
    Filed: January 17, 1992
    Date of Patent: October 5, 1993
    Assignee: Genetics Institute, Inc.
    Inventors: Randal J. Kaufman, S. Robert Adamson
  • Adaption of mammalian cell lines to high cell densities
    Patent number: H1532
    Abstract: Methods and nutrient media are disclosed useful for adapting mammalian cell lines to culture at increased cell densities.
    Type: Grant
    Filed: November 3, 1993
    Date of Patent: May 7, 1996
    Assignee: Genetics Institute, Inc.
    Inventors: S. Robert Adamson, Denis Drapeau, Yen-Tung Luan, Douglas A. Miller