Patents by Inventor Robert Alan LaRossa

Robert Alan LaRossa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Facile method for identifying regulated promoters
    Patent number: 6194159
    Abstract: A new method for the identification of useful promoters is disclosed. The method is capable of identifying bacterial promoters sensitive to a particular cellular insult and may be modified to identify promoters sensitive to herbicides and crop protection chemicals. Constructs comprising promoters upstream of a luminescent reporter genes are placed in transformed hosts. Transformants grown in liquid media to a predetermined growth stage and contacted with a cellular insult are assessed for regulatory region activity by measurement of the resulting change in bioluminescence. The method is able to identify promoters undetectable by standard methods.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: February 27, 2001
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Robert Alan LaRossa, Tina Kangas Van Dyk
  • Facile method for identifying regulated promoters
    Patent number: 6025131
    Abstract: A new method for the identification of useful promoters is disclosed. The method is capable of identifying bacterial promoters sensitive to a particular cellular insult and may be modified to identify promoters sensitive to herbicides and crop protection chemicals. Constructs comprising promoters upstream of a luminescent reporter genes are placed in transformed hosts. Transformants grown in liquid media to a predetermined growth stage and contacted with a cellular insult are assessed for regulatory region activity by measurement of the resulting change in bioluminesence. The method is able to identify promoters undetectable by standard methods.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: February 15, 2000
    Assignee: E. I. du Pont de Namours and Company
    Inventors: Robert Alan Larossa, Tina Kangas Van Dyk
  • Highly sensitive method for detecting environmental insults
    Patent number: 5683868
    Abstract: Subtle changes in environmental stress can now be detected and measured at sublethal levels as a generic response to environmental stress. The present invention provides a method to detect changes in the environmental stress level. The stress change is indicated as a change in the luminescence output of a genetically engineered microorganism. In the present invention, the luminescence gene complex is under the control of a stress inducible promoter.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: November 4, 1997
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Robert Alan LaRossa, William Robert Majarian, Tina Kangas Van Dyk