Abstract: The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.

Abstract: The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20 (pegylated ADI derived from M. hominis), but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.

Abstract: Provided are chimeric arginine deiminases, including pegylated chimeric arginine deiminases, and related compositions and methods of use thereof, including methods of treating cancer.

Abstract: The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.

Abstract: Provided are chimeric arginine deiminases, including pegylated chimeric arginine deiminases, and related compositions and methods of use thereof, including methods of treating cancer.

Abstract: The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.

Abstract: The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.

Abstract: A detection system and method are provided having vehicle-mounted and manportable mobile surveillance capabilities with minimal equipment redundancy. The system comprises a vehicle-mounted sensor unit, a hand-held unit, a manportable unit and a vehicle-mounted air collector unit. The vehicle-mounted sensor unit comprises a spectroscopy subsystem that is configured to direct light onto a surface outside the vehicle and to capture scattered optical energy from the surface outside the vehicle while the vehicle is moving. The hand-held unit may be removably mounted to the air collector unit to interrogate airborne particles in collected air. The hand-held unit is removable from the air collector unit and is connected to the manportable unit by a cable so as to form an integrated portable detection system for mobile surveillance away from the vehicle by a user.

Abstract: An air sampler module is provided for use with a detection device that monitors liquids and/or solids on a surface using spectroscopy techniques. The air sampler module comprises a housing, an intake port for collecting air containing airborne threats to be analyzed by the detection device, and a port to permit communication of an optical transceiver of the detection device into the housing to permit analysis of the collected air. Thus, the capabilities of a spectroscopy detection system are expanded to include the ability to analyze airborne threats.

Abstract: A system and method are provided for detecting non-fluorescing aerosol particles of biological origin within ambient background aerosol particles using Raman spectroscopy.

Abstract: An air sampler module is provided for use with a detection device that monitors liquids and/or solids on a surface using spectroscopy techniques. The air sampler module comprises a housing, an intake port for collecting air containing airborne threats to be analyzed by the detection device, and a port to permit communication of an optical transceiver of the detection device into the housing to permit analysis of the collected air. Thus, the capabilities of a spectroscopy detection system are expanded to include the ability to analyze airborne threats.