Patents by Inventor Robert Anthony Mook, Jr.

Robert Anthony Mook, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidineamines as angiogenesis modulators
    Patent number: 7858626
    Abstract: Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Grant
    Filed: July 30, 2007
    Date of Patent: December 28, 2010
    Assignee: GlaxoSmithKline LLC
    Inventors: Amogh Boloor, Mui Cheung, Ronda Gayle Davis-Ward, Philip Anthony Harris, Kevin Hinkle, Christopher P. Lauderman, Robert Anthony Mook, Jr., Jeffery Alan Stafford, James Marvin Veal
  • Imidazopyridine Kinase Inhibitors
    Publication number: 20100216779
    Abstract: The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
    Type: Application
    Filed: May 28, 2008
    Publication date: August 26, 2010
    Inventors: Eric W. Baum, Kyle Allen Emmitte, Kevin Wayne Kuntz, Robert Anthony Mook, JR., Kristen Elizabeth Nailor, James Michael Salovich, John Brad Shotwell, Stephon Cornell Smith, Kirk Lawrence Stevens, David Edward Uehling, Alex Gregory Waterson, Mui Cheung, Ganesh S. Moorthy, Brian John Wilson
  • Pyrimidine compounds
    Patent number: 7514446
    Abstract: The present invention provides compounds of formula (I): wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.
    Type: Grant
    Filed: February 11, 2004
    Date of Patent: April 7, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Ronda Davis-Ward, Robert Anthony Mook, Jr., Michael J Neeb, James M Salovich
  • Imidazotriazine compounds
    Patent number: 7462614
    Abstract: The present invention provides compounds of formula (I): wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: December 9, 2008
    Assignee: Smithkline Beecham Corporation
    Inventors: Mui Cheung, Nigel Paul King, Kevin Wayne Kuntz, Robert Anthony Mook, Jr., Mark Andrew Pobanz, James Michael Salovich, Brian John Wilson
  • Pyrimidineamines as angiogenesis modulators
    Patent number: 7262203
    Abstract: Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: August 28, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Amogh Boloor, Mui Cheung, Ronda Davis, Philip Anthony Harris, Kevin Hinkle, Robert Anthony Mook, Jr., Jeffery Alan Stafford, James Marvin Veal
  • Pyrimidineamines as angiogenesis modulators
    Patent number: 7105530
    Abstract: Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also Includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: September 12, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Amogh Boloor, Mui Cheung, Ronda Davis, Philip Anthony Harris, Kevin Hinkle, Robert Anthony Mook, Jr., Jeffery Alan Stafford, James Marvin Veal
  • Substituted isoquinolines as ultra short acting neuromuscular blockers
    Patent number: 6187789
    Abstract: Ultrashort acting neuromuscular blocking agents of Formula (I) which are useful as skeletal muscle relaxants during emergency intubation procedures, routine surgery and post-operative settings are disclosed, wherein: X is a halogen; h is from 1 to 2; Y is hydrogen or methoxy; Z1 and Z2 are methyl; W1 and W2 are carbon; and A is a pharmaceutically acceptable anion.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: February 13, 2001
    Assignees: Glaxo Wellcome Inc., Cornell Research Foundation Inc.
    Inventors: Eric Cleveland Bigham, Grady Evan Boswell, John Joseph Savarese, Roy Archibald Swaringen, Jr., Sanjay Shashikant Patel, Eric Eugene Boros, Robert Anthony Mook, Jr., Vincente Samano
  • Substituted isoquinolines as ultra short acting neuromuscular blockers
    Patent number: 6177445
    Abstract: Ultra short acting neuromuscular blocking agents of Formula (I) which are useful as skeletal muscle relaxants during emergency intubation procedures, routine surgery and post-operative settings are disclosed, wherein q and t are independently from 0 to 4; X1 and X2 are independently halogen; ha and hb are independenity from 0 to 2; Z1 and Z2 are indepentdently hydrogen, C1-6 alkyl, C2-6 alkenyl or C2-6 alkynyl with the proviso that Z1 and Z2 are not both hydrogen; Y1, Y2, and Y3 and Y4 are independently hydrogen, halogen or C1-3 alkoxy; m and p are independently 1 to 6; n and r are independently 0 to 4; with the proviso the if ha and hb are both 0, then r is 0 and n is 0 to 2; R1 to R14 are independently hydrogen, halogen, C1-3 alkoxy, or R2 and R3 together with the carbon atoms to which they are bonded, R5 and R6 together with the carbon atoms to which they are bonded, R9 and R10 together with the carbon atoms to which they are bonded, R12 and R13 together with the carbon atoms to which they are bonded, may
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: January 23, 2001
    Assignees: Glaxo Wellcome Inc., Cornell Research Foundation Inc.
    Inventors: Eric Cleveland Bigham, Grady Evan Boswell, John Joseph Savarese, Roy Archibald Swaringen, Jr., Sanjay Shashikant Patel, Eric Eugene Boros, Robert Anthony Mook, Jr., Vincente Samano