Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a Disease resistant soybean plant or germplasm using genes derived from Glycine canescens, Glycine clandestina, Glycine tomentella. A soybean plant or germplasm that has been identified, selected and/or produced by any of the methods of the present invention is also provided. Disease resistant soybean seeds, plants and germplasms are also provided.

Abstract: The present invention relates to methods and compositions for identifying, selecting and/or producing a disease resistant soybean plant or germplasm using markers, genes and chromosomal intervals derived from Glycine canescens P1440935, P1483193, P1595799, or a progeny thereof, or Glycine tomentella, or a progeny thereof. A soybean plant or germplasm that has been identified, selected and/or produced by any of the methods of the present invention is also provided. Disease resistant soybean seeds, plants and germplasms are also provided.

Abstract: Provided here are methods of using a mutated patatin-like phospholipase II? (“pPLAII?,” renamed here MATRILINEAL) to induce haploid induction in plants, cloning a pPLAII? to induce haploid induction in plants, and genetically engineering a plant to contain a mutated pPLAII?. Also provided are methods of applying topical and spray chemicals, lipids, and RNAi molecules to plants during pollination in order to induce haploid production. Further provided are methods of chemically treating plants during pollination to induce haploids while also reducing embryo abortion and increasing seed set.

Abstract: A process for the hydroformylation of olefins to aldehydes is disclosed. The process comprises: hydroformylating one or more olefins with hydrogen and carbon monoxide in the presence of a ligand-rhodium catalyst in a reaction zone; recovering a reactor effluent from the reaction zone, the reactor effluent comprising product aldehyde and the ligand-rhodium catalyst; passing the reactor effluent and a strip gas to a vaporiser, wherein the strip gas comprises carbon monoxide and is formed from a recycle strip gas stream and a make-up strip gas stream, wherein the product aldehyde is vaporised into the strip gas in the vaporiser resulting in a vapour mixture, comprising the strip gas and the product aldehyde, and a liquid mixture, comprising the ligand-rhodium catalyst; recovering the liquid mixture and recycling the ligand-rhodium catalyst to the reaction zone; recovering the vapour mixture and separating the product aldehyde from the vapour mixture.

Abstract: A method for making a cold plate includes the steps of positioning a finstock structure in a cavity of a substrate; and applying a cover to the finstock structure and substrate, wherein the applying step comprises ultrasonically additive manufacturing the cover to the substrate and the finstock structure, whereby the cover joins with the substrate and the finstock structure. The resulting cold plate assembly includes a substrate having a cavity, a finstock structure within the cavity, and a cover closing the finstock structure within the cavity, the cover being integrally joined to the substrate and to the finstock structure.

Abstract: Provided here are methods of using a mutated patatin-like phospholipase II? (“pPLAII?,” renamed here MATRILINEAL) to induce haploid induction in plants, cloning a pPLAII? to induce haploid induction in plants, and genetically engineering a plant to contain a mutated pPLAII?. Also provided are methods of applying topical and spray chemicals, lipids, and RNAi molecules to plants during pollination in order to induce haploid production. Further provided are methods of chemically treating plants during pollination to induce haploids while also reducing embryo abortion and increasing seed set.

Abstract: A clipless cycling shoe having an upper and a base plate. The base plate has a medial portion, a lateral portion and a medial sidewall. The medial portion has a rigid support structure having a top portion and a bottom portion, a cavity is formed between the top portion and bottom portion, wherein the cavity is filled with a core material. The lateral portion has a lateral plate. The medial sidewall wrap is adjacent the medial portion and extends outward and upward relative to the base plate and the medial sidewall wrap extends a portion of the length of the base plate. The medial portion is desirably thicker than the lateral portion.

Abstract: A void between two or more composite laminate parts is filled by a composite laminate filler that is laid up and integral with at least one of the parts.

Abstract: A shoe includes an outsole, a first upper portion, a second upper portion, a rotary dial mounted to the first upper portion, and first and second lace portions coupled between the rotary dial and the second upper portion. The first lace portion aligns with a heel region of the shoe, the second lace portion aligns with a pedal region of the outsole, and a closure center line aligns with a medial arch region of the outsole. The second upper portion includes first and second lace guides. The first upper portion includes a third lace guide between the first and second lace portions. The first and second lace portions define a unitary lace extending from the rotary dial, through the first, second, and third lace guides, and back to the rotary dial. No portion of the lace member crosses over another portion of the lace member outside of the rotary dial.

Abstract: A microbial infection in an eye of a subject is treated or prevented by topically administering to the eye an effective amount of a macromolecule or a pharmaceutically acceptable salt thereof that includes a dendrimer of 1 to 8 generations with one or more sulfonic acid- or sulfonate-containing moieties attached to one or more surface groups of the outermost generation of the dendrimer. Compositions containing the macromolecule or salt are useful in these methods.

Abstract: Provided herein are dendrimers comprising: a core unit, five generations of building units which are lysine residues or analogues thereof, first terminal groups comprising a cabazitazel residue covalently attached to a diglycolyl linker group, and second terminal groups comprising a PEG group. Also provided herein are pharmaceutical compositions comprising the dendrimers, and methods and uses of the dendrimers in therapy of disorders such as cancers. Processes for making the dendrimers and intermediates are also provided.

Abstract: A bone preparation system kit includes a hand piece, tubing coupled to an input of the hand piece, and a nozzle with a nozzle tip coupled to an output port of the hand piece. The hand piece includes an internal passageway extending there through from the inlet port to the outlet port for forming a flow path and further includes a valve stem supported therein for movement across the internal passageway for opening and closing the internal passageway wherein flow along the flow path is blocked by the valve stem. The hand piece also includes a trigger configured to move the valve stem to thereby control the flow of fluid through the hand piece. The hand piece, nozzle, and tubing are sterilized and enclosed in a package, such as plastic or metal foil package, including a plastic or metal foil pouch, which is configured to maintain the sterilization of said bone preparation system.

Abstract: A method for plugging a subset of cells of a honeycomb structure that includes: covering a first end face of the honeycomb structure with a mask that comprises a body and a plurality of openings, wherein the plurality of openings of the mask is coincident with a plurality of cells of the honeycomb structure; providing a plug of material upon a film material; applying a force to the film material with a piston to push the plug of material through the plurality of openings of the mask and into the plurality of cells of the honeycomb structure; and measuring a plurality of pressures within the plurality of cells of the honeycomb structure during the applying step.

Abstract: A system for emulating a subject, to allow a user to interact with a computer generated talking head with the subject's face and voice; said system comprising a processor, a user interface and a personality storage section, the user interface being configured to emulate the subject, by displaying a talking head which comprises the subject's face and output speech from the mouth of the face with the subject's voice, the user interface further comprising a receiver for receiving a query from the user, the emulated subject being configured to respond to the query received from the user, the processor comprising a dialogue section and a talking head generation section, wherein said dialogue section is configured to generate a response to a query inputted by a user from the user interface and generate a response to be outputted by the talking head, the response being generated by retrieving information from said personality storage section, said personality storage section comprising content created by or about

Abstract: Wellbore systems containing a hydraulically regulated primary safety valve may have their hydraulic regulation transferred to an insert safety valve disposed in a nipple. Transfer of the hydraulic regulation may take place mechanically, such as through axial displacement of a sliding sleeve or by replacement of a hydraulic spool. Wellbore systems configured for axial displacement of a switching mechanism may comprise: a tubing string comprising a nipple and a primary safety valve, the primary safety valve being disposed in the tubing string above or below the nipple; a control line and a balance line in hydraulic communication with the primary safety valve and in latent hydraulic communication with an internal flow pathway within the nipple; and a switching mechanism that is axially displaceable to establish hydraulic communication between an insert safety valve positioned in a bore of the nipple and both the control line and the balance line.

Abstract: A method for plugging a subset of cells of a honeycomb structure that includes: covering a first end face of the honeycomb structure with a mask that comprises a body and a plurality of openings, wherein the plurality of openings of the mask is coincident with a plurality of cells of the honeycomb structure; providing a plenum, a movable plunger and a flow plate; positioning a cylinder between the honeycomb structure and the plenum; dispensing a plugging material into the plenum; moving the plunger toward the flow plate with a force to push the plugging material through the flow plate into the cylinder, the moving generating a pressure in the plenum and the cylinder that forces the plugging material through the mask into the plurality of cells of the honeycomb structure to a predetermined depth; and determining the pressure within the cylinder during the moving of the plunger.

Abstract: A gas turbine engine includes a liner positioned within a compressor section or a turbine section of the gas turbine engine and at least partially defining a core air flowpath through the gas turbine engine. The gas turbine engine also includes a casing at least partially enclosing the liner. Additionally, the gas turbine engine includes a pressure sensor assembly having a body, an extension member, and a pressure sensor. The pressure sensor is positioned at least partially within the body and the body is positioned at least partially on an outer side of the casing, the extension member extending from the body through a casing opening in the casing and towards a liner opening in the liner. The extension member defines a continuous sense cavity exposing the pressure sensor to the core air flowpath.

Abstract: Systems and methods are provided for managing organizational or corporate structures, including the employee roles or activities administered by human resources. A portion of the role datasets received within human resource records may be used to generate role tokens comprising unique datasets that have been truncated and deduped. Such tokens may be extracted based on assigned prioritization scores, and further assigned training labels representing categorical levels. Predictive labels may be assigned to a remaining portion of the extracted tokens via a logistic regression classifier, and a model organizational dataset may be generated based on the assigned training labels and the assigned predictive labels. The prediction certainty of the role tokens in the model organizational dataset may be used to map the identified role tokens to the roles represented in the human resource records.

Abstract: A sternotomy closure technique is suitably carried out with a cerclage mechanism, which is capable of maintaining proper bony compression (within a desired range) across the sternum cut, in spite of a range of external forces and significant lateral distraction due to these external forces. The sternum fragments are aligned in apposition disposed around a longitudinal seam and secured with a resilient element. The resilient element is tensioned to a desired tension to compress the sternum to a desired compression range. The resilient element is then elongated and contracted while accepting multiple cycles of physiological distracting forces across the sternum while maintaining contact pressure across the longitudinal seam within a desired range for a length of time sufficient for bony healing. The resilient element is preferably a polymer cable comprising an elongated elastic polymeric core coaxially surrounded by a sheath woven from ultra-high molecular weight polyethylene strands.