Abstract: A system and method for ascertaining the identity of an object within an enclosed article. The system includes an acquisition subsystem utilizing a stationary radiation source and detector, a reconstruction subsystem, a computer-aided detection (CAD) subsystem, and a 2D/3D visualization subsystem. The detector may be an energy discriminating detector. The acquisition subsystem communicates view data to the reconstruction subsystem, which reconstructs it into image data and communicates it to the CAD subsystem. The CAD subsystem analyzes the image data to ascertain whether it contains any area of interest. Any such area of interest data is sent to the reconstruction subsystem for further reconstruction, using more rigorous algorithms and further analyzed by the CAD subsystem. Other information, such as risk variables or trace chemical detection information may be communicated to the CAD subsystem to be included in its analysis.

Abstract: A method of improving a signal to noise ratio of an image data set of a cargo container is disclosed. The method includes transmitting a radiation beam toward the cargo container, detecting the transmitted radiation beam via a plurality of area radiation detectors, each area radiation detector comprising an active area defined by a matrix of pixels, thereby defining enhanced radiation data, processing the enhanced radiation data and reconstructing the image data set representative of contents of the cargo container, combining image attributes of the image data set to improve the signal to noise ratio, thereby defining an enhanced image data set, and displaying on a display the enhanced image data set comprising an improved signal to noise ratio.

Abstract: A method for detecting, quantifying, staging, reporting, and/or tracking of a disease includes providing analysis software configured to detect, quantify, stage, report, and/or track a disease utilizing images of a patient. The analysis software is executable on a personal computer of a patient. Patients are then imaged utilizing a medical imaging apparatus and medical images of the patient produced by the imaging apparatus are downloaded to the personal computer of the patient. The imaging and downloading are repeated a plurality of times at intervals selected to provide the analysis software with sufficient images to detect, quantify, stage, report, and/or track the disease in the patient.

Abstract: A method for processing medical images for use in the detection and diagnosis of disease comprises classifying regions of interest within the medical images based on a hierarchy of anatomical models and signal models of signal information of an image acquisition device used to acquire the medical images. The anatomical models are derived to be representative of anatomical information indicative of a given disease. A computer-aided system for use in the diagnosis and detection of disease comprises an image acquisition device for acquiring a plurality of image data sets and a processor adapted to process the image data sets. The processor is adapted to classify selected tissue types within the image data sets based on a hierarchy of signal and anatomical models and the processor is further adapted to differentiate anatomical context of the classified tissue types for use in the diagnosis and detection of disease.

Abstract: A system and a method for detecting an object, such as an explosive device or material, located within a closed article, such as a piece of luggage or a parcel. The system includes an acquisition subsystem for acquiring information pertaining to a specific object, a reconstruction subsystem for reconstructing acquired information pertaining to the specific object into image data, and a computer-aided detection subsystem adapted for identifying the specific object through the use of differential operators. The method includes obtaining image data of the one object, computing a differential operator for each voxel of the image data, computing eigenvalues and eigenvectors for each of the voxels, and computing a scalar function of the eigenvalues to ascertain whether each of the voxels represents a portion of the one object.