Patents by Inventor Robert B Den

Robert B Den has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diffusing Alpha-emitter Radiation Therapy with Enhanced Beta Treatment
    Publication number: 20250367470
    Abstract: A radiotherapy source includes a base and radioactive atoms of one or more isotopes, which are attached to the base. The radioactive atoms have a radon release rate of at least 0.5 micro-Curie (?Ci) per centimeter length, and emit beta radiation achieving at 2 millimeters from the base an asymptotic dose of at least 10 Gy. Additionally, the ratio between the beta radiation asymptotic dose at a distance of 2 millimeters from the device to the radon release rate, is greater than 15 Gy/(microcurie/cm).
    Type: Application
    Filed: January 29, 2025
    Publication date: December 4, 2025
    Inventors: Lior Arazi, Robert B Den, Michael Schmidt, Ofer Magen, Itzhak Kelson, Amnon Gat
  • Diffusing alpha-emitter radiation therapy with enhanced beta treatment
    Patent number: 12246191
    Abstract: An interstitial source including a base suitable for implanting in a tumor and radioactive atoms of one or more isotopes, which are attached to the base. The radioactive atoms have a radon release rate of at least 0.5 micro-Curie (?Ci) per centimeter length, and emit beta radiation achieving at 2 millimeters from the base an asymptotic dose of at least 10 Gy. Additionally, the ratio between the beta radiation asymptotic dose at a distance of 2 millimeters from the device, to the radon release rate, is greater than 15 Gy/(microcurie/cm).
    Type: Grant
    Filed: October 4, 2023
    Date of Patent: March 11, 2025
    Assignee: Alpha Tau Medical Ltd
    Inventors: Lior Arazi, Robert B Den, Michael Schmidt, Ofer Magen, Itzhak Kelson, Amnon Gat
  • Diffusing alpha-emitter radiation therapy with enhanced beta treatment
    Patent number: 11857803
    Abstract: An interstitial source including a base suitable for implanting in a tumor and alpha emitting atoms attached to the base, with a concentration of at least 6 ?Ci per centimeter length. The alpha emitting atoms are attached to the base, with a desorption probability upon radioactive decay of not more than 30%.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: January 2, 2024
    Assignee: ALPHA TAU MEDICAL LTD.
    Inventors: Lior Arazi, Robert B Den, Michael Schmidt, Ofer Magen, Itzhak Kelson, Amnon Gat
  • Diffusing Alpha-Emitter Radiation Therapy with Enhanced Beta Treatment
    Publication number: 20220184418
    Abstract: An interstitial source including a base suitable for implanting in a tumor and alpha emitting atoms attached to the base, with a concentration of at least 6 ?Ci per centimeter length. The alpha emitting atoms are attached to the base, with a desorption probability upon radioactive decay of not more than 30%.
    Type: Application
    Filed: December 14, 2021
    Publication date: June 16, 2022
    Inventors: Lior Arazi, Robert B Den, Michael Schmidt, Ofer Magen, Itzhak Kelson, Amnon Gat